Wrap Up Gout Arthritis

8/11/2019 Wrap Up Gout Arthritis

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WRAP UP PBL

SKENARIO 1 MUSKULOSKELETAL

SULIT MENGGERAKKAN SENDI SIKU

Disusun oleh:

KELOMPOK A-2

KETUA : ADITYA NUGRAHA ARTAR (11020100!"

#EKRETARI#: A$IYYA %ARAH PUTRI (11020100"

ANGGOTA : ADELIA PUTRI #A$RINA(11020100&"

ADELINA ANNI#A PERMATA (11020100'"

ADINDA AMALIA #HOLEHA (11020100"

LALU RE)A ALDIRA AK$AR (11020101*"

ADIYATY YUNITA P+P+ (110201100!"

ANDRIANA ,IAYA (110201102"

INTAN NURUL HIKMAH (110201112!"

ADITYA ,I.AK#ONO (110201200"

UNIVERSITAS YARSI

l+ Le/+ en+ #u3/o+ .e4353 Pu/ih6 353/3 Pus3/+ DKI 353/3+ Inonesi3+ 10&10+Teleon: 7'2 21 *20''&+

0


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Skenario:

SULIT MENGGERAKKAN SENDI SIKU

#eo3n8 l35i-l35i *& /3hun6 3/3n8 5e R#UD en83n 5eluh3n /e33/ 9enol3n

isi5u 53n3n se35 2 9ul3n ini+ $enol3n i3s353n n;ei 3n 9een;u/ se/3

4en883n88u en/3n8 8e35 (range of movement < ROM"+ Ri=3;3/ en3h 9en8535

5e4e3h3n 33 4e/3/3soh3l3n8e3l I i3l34i & 9ul3n ;3n8 l3lu 3n 9e5u3n8

se/el3h 4e4inu4 o93/ 3n/i n;ei+ P33 e4ei5s33n >isi5 i33/53n tophus 33

se5i/3 olecranon9en/u5 9ul3/ en83n i34e/e !?4+ H3sil e4ei5s33n l39o3/oiu4

i33/i h;eue?e4i3+ Do5/e 4e49ei53n nons/eoi 3n/i in>l343si u8 (N#AID"

3n ui?osui? 33 3sien /ese9u/ is33n53n un/u5 il35u53n e4ei5s33n

3iolo8i+

1


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4/38

D ,i-o!e%a

Go#! Ar!.ri!i% a/a$a. -en0aki! 0an' /i%e+a+kan o$e. -en#&-#kan Kri%!a$ a%a&

#ra! -a/a %en/i Penin'ka!an a%a& #ra! /i%e+a+kan karena !era/in0a 'an''#an

-a/a &e!a+o$i%&e -#rin Pen0aki! ini &en'e$#arkan 'ea$a in2$a&a%i %e-er!i

n0eri /an +er/en0#! Pe&+erian o+a! NSAID /an #ri3o%#ri3 /a-a! &enan'ani-en0aki! ini

E Sa%aran Be$aar

LI+1+ Me43h34i 3n Menel3s53n An3/o4i #eni Tu9uh 3n %un8si Al3/ Ge35

1+1 M35os5ois

1+2 Mi5os5ois

LI+2+ Me43h34i 3n Menel3s53n Me/39olis4e 3n #e5esi As34 U3/

LI++ Me43h34i 3n Menel3s53n A/hi/is Gou/

+1 De>inisi A/hi/is Gou/

+2 E/iolo8i A/hi/is Gou/

+ P3/o>isiolo8i A/hi/is Gou/

+* M3ni>es/3si Klini5 A/hi/is Gou/

+& Di38nosis 3n Di38nosis $3nin8 A/hi/is Gou/

+' Ko4li53si A/hi/is Gou/

+ Pe4ei5s33n Penun3n8

+! T3/3l35s3n3 A/hi/is Gou/

+B Pen?e83h3n A/hi/is Gou/

+10 Po8nosis A/hi/is Gou/

LI+*+ Me43h34i 3n Menel3s53n G34933n R3iolo8is A/hi/is

LI+&+ Me43h34i 3n Menel3s53n Golon83n o93/ N#AID 3n ui?osui?


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LI1 Me&a.a&i /an Mene$a%kan Ana!o&i Sen/i T#+#. /an 4#n'%i A$a! Gerak

1+1 M35os5ois An3/o4i #eni Tu9uh 3n %un8si Al3/ Ge35

EKSTREMITAS SUPERIOR

*


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7/38

Ge35 seni : %le5si 3n e5s/ensi

E5s/e4i/3s 93=3h

'


8/38

EKSTREMITAS IN4ERIOR

a Ar!i3#$a!io in2eriori% $i+eri 5ar!i3#$a!io 3o8ae7

Tul3n8 : A?e/39ulu4 3n ?3u/ >e4ui

Ge35 seni : %le5si6 e5s/ensi6 39u5si6 3u5si6 enoo/3si6e5soo/3si+ Ar!i3#$a!io 'en#%

Tul3n8 : .on;lus 4ei3lis >e4ois 3n ?on;lus4ei3lis /i9i3e

Ge35 seni : %le5si6 e5s/ensi 6 o/3si 4ei3lis6 >le5si l3/e3lis+

3 Ar!i3#$a!io !i+io 2i+#$ari%

Tul3n8 : %3?ies 3/i?ul3is >i9ul3is en83n >3?ies3/i?ul3is ?3i/is

>i9ul3e

Ge35 seni : Gese53n 5e 3/3s 3n 5e 93=3h

/ Ar!i3#$a!io !a$o3r#$a$i%

Tul3n8 : An/33 /o?hle3/3li 3n len85un8 ;3n8 i9en/u5oleh 43leoli

oss3 ?uis Ge35seni : Pl3n/3 %leFi6 Dosi %leFi6 InCesio 3n ECesio+

e Ar!i3#$a!io Pe/i%

Ar!i3#$a!io !a$o3a$3anea

Tul3n8 : Os /3lus 3n Os ?3l?3neus

Ge35 seni : 8liin8

Ar!i3#$a!io !a$o3a$3aneona9i3#$ari%

Tul3n8 : Os /3lus6 Os ?3l?3neus 3n Os ?u9oieu4

Ge35 seni : Gese 3n o/3si

Ar!i3#$a!io 3a$3aneo3#+oi/ea

Tul3n8 : Os ?3l?3neus 3n Os ?u9oieu4 Ge35 seni : Gese 3n sei5i/ o/3si

Ar!i3#$a!io !ar%o&e!a!ar%a$e%

Tul3n8 : Os /3si 3n Os 4e/3/3si

Ge35seni : Pl3n3

Ar!i3#$a!io Me!a!ar%o-.a$an'ea$e%

Tul3n8 : Os 4e/3/3si 3n Os h3l3n8e3les

Ge35 seni : >le5si6 e5s/ensi6 39u5si6 3u5si

Ar!i3#$a!ione% In!er-.a$an'ea$e% Pe/i%

Tul3n8 : In/e h3l3n8e3les

Ge35 seni : >le5si 3n e5s/ensi

K$a%i2ika%i Per%en/ian
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9/38

1 S0nar!.ro%i%

#eni ;3n8 /i35 9e8e35 s343 se53li+ #eni ini ies3/u53n oeh 3in83ni53/ 33/ >i9os3+ $e3s353n 5o4osisi 3i 93h3n ;3n8 4en8isi e/e4u3n

5eu3 seni i938i 4en3i :

3+ #u/u36 i3n/33 /ul3n8 /e33/ 3in83n >i9os3 ;3n8 /iis se53li6 ?on/oh:

su/u3 s38i/3lis6 su/u3 l349oie36 su/u3 ?oonoie3

9+ #;nes4osis6 i3n/33 /ul3n8 /e33/ 3in83n >i9os3

(li834en/u4i9os36 Me4933n s;noCi3lis6 Pli?3

s;noCi3lis6 illi s;noCi3lis6 #;noCi36 Li834en/3 /eii 3i: Li834en/u4

eF/3?3sul3is6 Li834en/u4 ?3sul3is6 3n Li834en/u4 in/3?3sul3is+

$e3s353n 9en/u5 e4u533n seni 3n /ie e8e353n :

3+ A/hoie3 (8liin8" ise9u/ u83 seni lun?u (seni l3n3"6 4eu353n

eseni3n ;3n8 4e4un85in53n 8e35 o/3si 33 s3/u 9i3n8 3/3+ Ke3l3

seni 3n le5u5 seni 3/3+ $is3 53en3 34i3/hosis .on/oh: 3/+ In/e?33les6

3/+ In/e/3s3les6 3/+ #/eno?l3Ci?ul3is6 hu9un83n /ul3n8 e8el3n83n 535i+

#eni Lun?u (A/hoie3"

9+ Gin8l;4us (hin8" ise9u/ u83 seni en8sel6 4eu353n eseni3n ;3n8

4e4un85in53n 8e353n s3/u 33h+ An/33 e4u533n 5onCe5s 3n 5on53>+

!
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10/38

.on/oh: 3/+ .u9i/i6 3/+ T3lo?u3les6 3/+ In/eh3l3n8es6 seni si5u 3n/33

/ul3n8 len83n 3/3s 3n /ul3n8 h3s/3+

G3493 2+ #eni En8sel (Gin8l;4us"

?+ PiCo/ (/o?hoie3" 4eu353n e4u533n seni Ce/i?3l+ .on/oh: 3/+ A/l3n/o

3Fi3lis6 3/+ To?hoie3 (3iouln3is o5si43lis"

G3493 + #eni Ce/i?3l (PiCo/"

+ Ellisoie3 (?on;loie3" ise9u/ u83 seni u/36 4eu353n eseni3n

;3n8 4e4un85in53n 8e353n 9eu/3 (o/3si"+ Pe4u533n seni 9e9en/u5

eli+ .on/oh: 3/+ R3io?33l6 hu9un83n /ul3n8 /en85o35 en83n /ul3n8

9el353n8 I (3/l3s"+

G3493 *+ #eni u/3 (ellisoie3"

e+ #heoie3 (3 93ll 3n so?5e/" ise9u/ u83 seni eluu6 4eu353n

eseni3n ;3n8 4e4un85in53n e8e353n 5e se83l3 33h+ Ke3l3 seni

see/i 9en/u5 9ol3 43su5 5e3l34 le5u5 seni ;3n8 3l34+ .on/oh: 3/+

.oF3e6 hu9un83n /ul3n8 len83n 3/3s en83n /ul3n8 9eli53/+

G3493 &+ #eni eluu (#heoie3"

>+ #ell3is (s3le" ise9u/ u83 seni el3n36 4eu353n eseni3n ;3n8

4e4un85in53n 9e9e33 8e353n o/3si6 n34un /i35 5e se83l3 33h+ Ke3l3

seni 3n le5u5 seni see/i o3n8 uu5 i3/3s l3n3 5u3+ .on/oh: 3n/33

/3eiu4 3n 4e/3?33l6 hu9un83n /ul3n8 /el335 /3n83n 3n 3i /3n83n+

B
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11/38

G3493 '+ #eni el3n3 (#ell3is"

Bidang khayal tubuh:

Bidang coronal6 4e4938i /u9uh 4en3i 3n/eio 3n os/eio6 su49u

8e35n;3 s38i//3l

Bidang sagittal6 4e4938i /u9uh 4en3i eF/3 3n sinis/36 su49u 8e35n;3

>on/3l

Bidang transversal6 4e4938i /u9uh 4en3i sueio 3n in>eio su49u

8e35n;3 Ce/i?3l

Gerak sendi tubuh:

Fleksi, 8e353n ;3n8 4ene53/53n 938i3n 3i /ul3n8 ;3n8 4e49en/u5 seni

Ekstensi6 8e35 9el3=3n3n 3i >le5si

Abduksi, 8e35 33h sisi 4en3uhi 9i3n8 s38i//3l

Aduksi, 8e35 ;3n8 9el3=3n3n 33h en83n 39u5sile5si 5e 33h s34in8 Sirkumdiksi, 839un83n 8e35 o/3si (>le5si6 l3/eo>le5si6 e5s/ensi"

1+2 Mi5os5ois An3/o4i #eni Tu9uh 3n %un8si Al3/ Ge35

Peseni3n 33l3h /e43/ 9e/e4un;3 u3 3/3u /i83 unsu /ul3n86 93i5

/ul3n8 3/3u /ul3n8 3=3n6 i53/353n se9383i seni 3/3u 3/i5ul3si+

#eni /e4oe /e33/ sel343 43s3 enu49uh3n : 4is3ln;3 ei>isis /ul3n8

3n3n8 4en;3/u en83n 938i3n 93/3n8 /ul3n8 4el3lui /ul3n8 3=3n hi3lin

3i is5us ei>isis+ #eni e4i5i3n 4en8hil3n8 9il3 enu49uh3n 9ehen/i

3n ei>isis 4en;3/u en83n 938i3n 93/3n8+ Te/3i 5e93n;353n seni9esi>3/ e43nen6 3n 33/ i8olon853n 9e3s353n ?ii susun3nn;3

4en3i 8olon83n u/343 : >i9os36 53/il38inos36 3n s;noCi3l+

Kl3si>i53si Peseni3n

a Sen/i 4i+ro%a

#eni ini ies3/u53n oleh 3in83n i53/ 33/ >i9os3+ $il3 en;3/u3n ini

s3n83/ 5u3/ seni ini ise9u/ su/u3+ #u/u3 h3n;3 /e33/ 33 /en85o35

3n /i35 9esi>3/ e43nen 53en3 3in83n >i9os3 en8i53/ i/u 33/

i83n/i oleh /ul3n8 i5e4ui3n h3i+ Pen;3/u3n /ul3n8 ;3n8 ih3sil53n i/u

i5en3l se9383i sinos/osis+ #eni 33 /ul3n8 ;3n8 ies3/u53n oleh

10
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12/38


13/38

R3=3n seni 4el3isi uun8-uun8 /ul3n8 en83n >un8si:

1+Melinun8i uun8 /ul3n8 383 /i35 3us+

2+Me4un85in53n e8e353n seni 4en3i 4ulus7

LI Me&a.a&i /an Mene$a%kan Me!a+o$i%&e /an Sekre%i A%a& Ura!

$iosin/esis uin 3n ii4iin i3/u 3n i5ooin3si53n en83n 5e/3/ oleh

4e53nis4e u43n 93li5 ;3n8 4en34in 383 =35/u 3n u4l3h ou5si 5eu3 3/

/ese9u/ sel3lu sesu3i en83n 5e9u/uh3n >isiolo8is ;3n8 9eC3i3si+ Pen;35i/ 8ene/i5

4e53nis4e uin 4en?35u 8ou/6 sino4 Les?h-N;h3n6 e>isiensi 3enosin

e34in3se6 en83n e>isiensi uin nu5leosi3 >os>oil3se+

As34 u3/ 33l3h 3s34 ;3n8 9e9en/u5 5is/3l-5is/3l ;3n8 4eu353n h3sil

35hi 3i 4e/39olis4e uin (9en/u5 /uun3n nu5leoo/ein"6 ;3i/u s3l3h s3/u

5o4onen 3s34 nu5le3/ ;3n8 /e33/ 33 in/i sel-sel /u9uh+ #e?33 3l34i3h6 uin

/e33/ 3l34 /u9uh 5i/3 3n iu43i 33 se4u3 4353n3n 3i sel hiu6 ;35ni

4353n3n 3i /3n343n (s3;u6 9u3h6 53?3n8-53?3n83n" 3/3u un he=3n (38in86

eo3n6i53n s3en"+

%un8si 3s34 u3/ 4e49en/u5 in/i-in/i sel+ N34un6 u4l3h ;3n8 ielu53n

/u9uh s3n83/ 5e?il+ #e?33 no43l /u9uh 4en8elu353n sis3n;3 4el3lui usus 3/3u un

>eses se93n;35 20 3n !0 sis3n;3 i5elu353n 3l34 9en/u5 uine en83ne3n/333n8in3l+

4i%io$o'i &e!a+o$i%&e /an %ekre%i

#e?33 3l34i3h6 uin /e33/ 3l34 /u9uh+ Tu9uh 4en;ei353n !& sen;3=3

uin un/u5 5e9u/uh3n se/i3 h3i+ A/in;3 5e9u/uh3n uin 3i 4353n3n h3n;31&+

Konsu4si 3l5ohol6 /elu6 i53n s3en6 3n eo3n-h3/i6 3n/un86 9393/6 li43-

4enin853/53n 533 3s34 u3/+ I/u 35i93/ 5e3 eni4 hio5s3n/in un/u5 4en8ol3h

uin 5i3n 9e3/+ A5i93/n;3 93n;35 sis3 3s34 u3/ i 3l34 33h6 9e9en/u5

9u/i3n63n 4en8u4ul i se5i/3 seni sehin883 4eni49ul53n n;ei+ As34 u3/

9ele9ih 9e3u en83n n3/iu4 3n 4e49en/u5 5is/3l n3/iu4 u3/+

12


14/38

Penin853/3n 533 3s34 u3/ seu4 33/ ise93953n oleh e49en/u53n

9ele9ih3n 3/3u enuun3n e5sesi 3s34 u3/6 3/3uun 5eu3n;3+ As34 u3/ 33l3h

ou5 35hi 4e/39olis4e uin+

#e?33 no43l6 4e/39olis4e uin 4en3i 3s34 u3/ 33/ i/e3n853nse9383i 9ei5u/:

#in/esis uin 4eli93/53n u3 3lu6 ;3i/u 3lu de novo 3n 3lu en8he43/3n

(salvage pathway"+

1+ 3lu e noCo 4eli93/53n sin/esis uin 3n 5e4ui3n 3s34 u3/

4el3lui e5uso nonuin+ #u9s/3/ 3=3ln;3 33l3h i9os3-&->os>3/6 ;3n8

iu93h 4el3lui se3n853i3n 3/ 3n/33 4en3i nu5leo/i3 uin (3s34

inosin3/6 3s34 8u3nil3/6 3s34 3enil3/"+

3lu ini i5en3li53n oleh se3n853i3n 4e53nis4e ;3n8 5o4le5s6 3n

/e33/ 9e9e33 eni4 ;3n8 4e4e?e3/ e35si ;3i/u: &-

>os>oi9osilio>os>3/ (PRPP" sin/e/3se 3n 34io>os>oi9osil/3ns>e3se

(34io-PRT"+ Te33/ su3/u 4e53nis4e inhi9isi u43n 93li5 oleh

nu5leo/i3 uin ;3n8 /e9en/u56 ;3n8 >un8sin;3 un/u5 4en?e83h

e49en/u53n ;3n8 9ele9ih3n+

2+ 3lu en8he43/3n 33l3h 3lu e49en/u53n nu5leo/i3 uin 4el3lui

93s3 uin 9e93sn;36 e4e?3h3n 3s34 nu5le3/6 3/3u 3su3n 4353n3n+

3lu ini /i35 4el3lui 3/-3/ e3n/33 see/i 33 3lu e noCo+ $3s3

uin 9e93s (3enin6 8u3nin6 hioF3n/in" 9e5onens3si en83n PRPP

un/u5 4e49en/u5 e5uso nu5leo/i3 uin 3i 3s34 u3/+ Re35si ini

i53/3lisis oleh u3 eni4: hioF3n/in 8u3nin >os>oi9osil/3ns>e3se

(HGPRT" 3n 3enin >os>oi9osil/3ns>e3se (APRT"+

Ek%kre%i A%a& Ura!

1
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15/38

As34 u3/ ;3n8 /e9en/u5 3i h3sil 4e/39olis4e uin 353n i>il/3si se?33

9e93s oleh 8lo4eulus 3n iesosi i /u9ulus o5si43l 8in3l+ #e938i3n

5e?il 3s34 u3/ ;3n8 iesosi 5e4ui3n ie5s5esi53n i ne>on is/3l 3n

i5elu353n 4el3lui uin+ E5s5esi ne//o 3s34 u3/ /o/3l 33 43nusi3 no43l

33l3h *00-'00 48


16/38

/i8lisei36 3n iuC3/+ Hieuise4i3 /e3i 53en3 5o49in3si

oCe 3n une e4e?3h3n 3i enin853/3n ATP:

o OCeou?/ion : enin853/3n sin/esis e-noCo 35i93/

enin853/3n PRPP6 ;3n8 ie5i353n 53en3 2 se939:

3+ Penin8353/3n 8lu-&- enin853/3n en/ose hosh3/e

3/h=3;6 enin853/3n R-'-Penin853/3n PRPP9+ $e5u3n8n;3 >ee93?5 inhi9i/ion /eh33 9iosin/esis e-

noCo sel343 hio8li5e4i3 enin853/3n eni4 34io

PRT 3n PRPP sin/esis+

o UneeF?e/ion: 53en3 33n;3 h3sil 4e/39oli/ ;3i/u

hiel35/e4i3 3n 5e/ono4ei3+

o Hieuise4i3 u83 ise93953n 8li5o8en s/o38e ise3ses 6 &6

'+

+ enuun3n eni4 >u5/os3 1 osh3/3se 3lol3se ( heei/3;

>u?/ose in/ole3n?e"6 ie/ /in88i >u5/os3 enin853/3n

e4353i3n ATP e49en/u53n 3s34 u3/6 n34un 3s34 l35/3/3n en3 /u9ul3 3siosis 4en8h3493/ e5s5esi 3s34 u3/ 3

enin853/3n e833si ATP6 enin853/3n e4353i3n 3s34 nu5le3/6

e?3hn;3 in/i sel 353n 4enin853/53n ou5si nu5leo/i3 uin6

oCeou?/ion AU6 33 he4ol;sis 5onis6 olis/e4i36 ll+

UneeF?e/ion AU 33 8in3l ise93953n 33 9e9e33: enuun3n

43s3 8in3lenuun3n >u5/os3 AU 3n e4353i3n o93/ (o93/ iue/i?"+

Gan''#an Ka!a+o$i%&e P#rin

1 A%a& Ura!M3nusi3 4en8u93h 3enosine 3n 8u3nosin 4en3i 3s34 u3/+ Aenosin 4ul3-

4ul3 iu93h 4en3i inosin oleh 3enosine e34in3se+ #el3in 33 i43/e /in853/

/in88i6 u3/3se 4en8u93h 3s34 u3/ 4en3i 3l3/oin6 su3/u ou5 ;3n8 l3u/ 3i 33

4343li3+ N34un6 53en3 43nusi3 /i35 4e4ili5i u3/3se6 ou5si 35hi 4e/39olis4e

uin 33l3h 3s34 u3/+ Pou5si 3s34 u3/ ;3n8 9ele9ih3n ini /e3i 53en3 5onsu4si

4353n3n ;3n8 /in88i uin+

$ei5u/ 9e9e33 4353n3n ;3n8 4en83nun8 533 uin /in88i:

3+ I53n /ei 3sin3"

e+ enis 5e3n8-5e3n83n

>+ D38in8 Pu;uh

8+ M3;on3ise

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17/38


18/38

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1


19/38

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20/38

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1B
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21/38

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in>l343si 3n 5eus353n 3in83n+

20


22/38

+* M3ni>es/3si Klini5 A/hi/is Gou/

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21


23/38

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seni

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s33"

Di38nosis 8ou/ i/e/353n 5e/i53 i33/53n 5i/ei3 A 3n


24/38

P%e#/o'o#!

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4en3hun ise/3i /o>us+

2


25/38

Keluh3n u/343 se3n83n 35u/ 3i 8ou/ 33l3h n;ei seni ;3n8 343/ s3n83/

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26/38

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27/38

3+ Pe4ei53s33n @-R3;

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28/38

Pen83/u3n ie/ se93i5n;3 se8e3 il35u53n 9il3 533 3s34 u3/ 4ele9ihi

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se9es3 &0-0 834


29/38

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2!


30/38

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2B


31/38

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0


32/38

Os/eo32/h2i/is

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33/38

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2


34/38

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35/38

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Dosis 5ol5isin 06&-06' 48


36/38

E2ek Sa&-in'

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33/ 4en883n88u /eu/343 en83n osis 435si43l+ $il3 e>e5 /e3i6

en8o93/3n h3us ihen/i53n =3l3uun e>e5 /e3i 9elu4 /e?33i+ Deesi

su4su4 /ul3n86 uu36 neui/is ei>e6 4io3/i6 3nui36 3loesi36 83n88u3n

h3/i6 e35si 3le8i6 3n ?oli/is he4o38i5 /e3i 53en3 osis ;3n8 9ele9ih3n

3n 33 e49ei3n I6 83n88u3n e5s5esi 35i93/ 5eus353n 8in3l 3n

5o49in3si 5e333n /ese9u/+ Kol5isin h3us i9ei53n h3/i-h3/i 33 3sien

usi3 l3nu/6 le43h 3/3u 3sien en83n 83n88u3n 8in3l6 53ioC3s5ul36 3n

s3lu3n ?en3+

2+ Alouinol

Alouinol 9e8un3 un/u5 4en8o93/i en;35i/ i3i 53en34enuun53n 533 3s34 u3/+ Pen8o93/3n 3n853 3n3n8 4en8u3n8i

>e5uensi se3n83n6 4en8h3493/ e49en/u53n /o>i6 4e4o9ilis3si 3s34 u3/

3n 4en8u3n8i 9es3n;3 /o>i+ Mo9ilis3si 3s34 u3/ 33/ i/in853/53n en83n

4e49ei53n ui5osui5+ Ke8un33n o93/ ini /eu/343 un/u5 4en8o93/i i3i

5oni5 en83n insu>isiensi 8in3l 3n 93/u u3/ 3l34 8in3l6 /e/3i osis 3=3l

h3us i5u3n8i+ O93/ ini u83 9e8un3 un/u5 en8o93/3n i3i se5une 35i93/

olisi/e4i3 Ce36 4e/3l3si3 4;eloi6 leu5e4i36 li4>o436 soi3sis6

hieuise4i3 35i93/ o93/6 3n 3i3si+

O93/ ini 9e5e3 en83n 4en8h3493/ F3n/in o5si3se6 eni4 u3n8

4en8u93h hioF3n/in 4en3i F3n/in 3n sel3nu/n;3 4en3i 3s34 u3/+Alouinol 4en8h3493/ sin/esis uin ;3n8 4eu353n e?uso F3n/in+

Alouinol 4en83l34i 9io/3ns>o43si oleh eni4 F3n/in o5si3se 4en3i

3loF3n/in ;3n8 43s3 3uhn;3 le9ih 3n3n8 3i33 3llouinol6 oleh 53en3

i/u 3llouinol ?u5u i9ei53n s3/u 53li seh3i 53en3 43s3 3uhn;3 ene5+

E>e5 s34in8 ;3n8 sein8 /e3i i3l3h e35si 5uli/+ $il3 5e4e3h3n

5uli/ /i49ul6 o93/ h3us ihen/i53n 53en3 83n88u3n 4un85in 4en3i le9ih

9e3/+ Allouinol 33/ 4enin853/53n >e5uensi se3n83n sehin883 se93i5n;3

33 3=3l /e3i i9ei53 5ol5isin+ #e3n83n 4en8hil3n8 se/el3h 9e9e33

9ul3n en8o93/3n+

Dosis un/u5 en;35i/ i3i in83n 200-*00 48


37/38

i93nin853n sul>ii3on6 /e/3i h3/i-h3/i e49ei3n 33 3sien ;3n8 en83n

i=3;3/ ul5us e/i?+ #3lisil3/ 4en8u3n8i e>e5 o9enesi+

Po9enesi 4en8h3493/ e5s5esi en3l 3i sul>ini3on6 ino4e/3sin6

enisilin6 PA#6 sul>on34ie6 3n u83 9e9383i 3s34 o83ni?6 sehin883 osis

o93/ h3us isesu3i53n 9il3 i9ei53n 9es3433n+ Dosis o9enesi 2 53li 2&048i 33

en;35i/ i3i oni5 9e3s353n h3493/3n e39so9si /u9ul3 3s34 u3/+

Ku3n8 e>e5/i> 4enuun53n 533 3s34 u3/ i93nin853n en83n 3llouinol

3n /i35 e>e5/i> 4en83/3si se3n83n i3i 35u/+ O93/ ini /i35 9oleh i9ei53n

33 3sien en83n i=3;3/ ul5us e/i?+ Ane4i36 leu5oeni36 383nulosi/osis

33/ /e3i+ #ul>ini3on 33/ 4enin853/53n e>e5 insulin 3n o93/

hio8li5e4i5 o3l sehin883 h3us i9ei53n 9es343 en83n o93/-o93/3n

see/i >enil9u/3on 3n o5si>eno9u/3on+

Dosis sul>inion 253li 100-200 48e5/i> 4ini43l+

&+ Ke/ool35

Meu353n o93/ 3n3l8esi? o/en en83n ee5 3n/i-in>l343si se3n8+

A9so9si o3l 3n IM 9el3n8sun8 ?e3/ 4en?33i un?35 3l34 0-&0 4eni/+

Dosis IM 0-'0 486 I 1&-0 486 3n o3l &-0 48+

E>e5 s34in8n;3 9eu3 n;ei i /e43/ sun/i53n6 83n88u3n s3lu3n

?en36 53n/u56 usin86 3n s35i/ 5e3l3 ;3n8 il3o53n /e3i 5i3-5i3 2 53lil3?e9o+ O93/ ini s3n83/ sele5/i> 4en8h3493/ .O@-16 4353 o93/ ini h3n;3

i3nu53n i353i /i35 le9ih 3i & h3i 53en3 5e4un85in3n /u535 l349un8

3n ii/3si l349un8 9es3 se53li+

'+ E/ool35

Meu353n N#AID 5elo4o5 3s34 i3no539o5sil3/ 3n o93/ ini

4eu353n le9ih sele5/i> /eh33 .O@-2 i93nin853n en83n N#AID

u4u4n;3+ E/ool35 4en8h3493/ 93i5in ;3n8 i5e/3hui 4eu353n s3l3h

s3/u 4ei3/o e3n8s3n8 n;ei+

M3s3 5e3n;3 ene5 sehin883 h3us i9ei53n -* 53li seh3i+

$e8un3 un/u5 3n3l8esi?6 3s?39e3h+ Dosis 200-*006 -* 53li seh3i+

'


38/38

DA%TAR PU#TAKA

Gun3=3n #G6 #e/i39u; R6 N3>i3li+ (200"+ Farmakologi dan $erapi ed %+

353/3 : %KUI

Leeson6 .+Rol3n+ An/hon; A+ P33o+ (1BB'"+Buku A&ar 'istologi Ed ! 353/3:

EG.+

M3nsoe6Ai>6 55+ (2001"+ )apita Selekta )edokteran edisi * +ilid + 353/3 :

%KUI

Mu3;6Ro9e/+K6 55+ (200B"+Biokimia 'arper Edisi -.+ 353/3 : EG.Pi?e6#;lCi3+A 3n ,ilson6Lo3ine+M+ (200&"+ /A$0F1S10L021 Edisi 3!

353/3 : EG.

Pu/6R+P39s/+ (2002"+ Sobotta 4 atlas anatomi manusia ed!--! &ilid 5 -! 353/3 :

EG.

Ro99ins 5u43! (-66.! Buku A&ar /atologi! Edisi -! +akarta 4 E27!

#uo;o A,655+ (200B"+ Buku A&ar 1lmu /enyakit 8alam edisi +ilid 111!

353/3 : In/en3 Pu9lishin8+

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