vii

DAFTAR ISI

HALAMAN JUDUL ................................................................................................ i

HALAMAN PENGESAHAN ................................................................................. ii

SURAT PERNYATAAN....................................................................................... iii

PRAKATA ............................................................................................................. iv

DAFTAR SINGKATAN ....................................................................................... vi

DAFTAR ISI ......................................................................................................... vii

DAFTAR GAMBAR .............................................................................................. x

DAFTAR TABEL .................................................................................................. xi

DAFTAR LAMPIRAN ......................................................................................... xii

INTISARI ............................................................................................................. xiii

BAB I PENDAHULUAN .................................................................................. 1

1.1. Latar Belakang ................................................................................. 1

1.2. Rumusan Masalah ........................................................................... 5

1.3. Tujuan Penelitian ............................................................................. 5

1.3.1. Tujuan Umum ........................................................................ 5

1.3.2. Tujuan Khusus ....................................................................... 5

1.4. Manfaat Penelitian ........................................................................... 6

1.4.1. Manfaat Teoritis ..................................................................... 6

1.4.2. Manfaat Praktis ...................................................................... 6

BAB II TINJAUAN PUSTAKA ......................................................................... 7

2.1. Kanker Leher Rahim ....................................................................... 7

2.1.1. Definisi Kanker Leher Rahim ................................................ 7

2.1.2. Epidemiologi Kanker Leher Rahim ....................................... 7

2.1.3. Etiologi Kanker Leher Rahim ................................................ 8

2.1.4. Faktor Resiko ......................................................................... 9

2.1.5. Manifestasi Klinis Kanker Leher Rahim ............................. 12

2.2. Pencegahan Kanker Leher Rahim ................................................. 13

2.2.1. Pap smear ............................................................................ 15

viii

2.3. Hubungan Tingkat Pengetahuan dan Sikap terhadap pemeriksaan

Pap Smear ..................................................................................... 32

2.4. Kerangka Teori .............................................................................. 34

2.5. Kerangka Konsep .......................................................................... 34

2.6. Hipotesis ........................................................................................ 35

BAB III METODE PENELITIAN ..................................................................... 36

3.1. Jenis Penelitian dan Rancangan Penelitian .................................... 36

3.2. Variabel dan Definisi Operasional ................................................ 36

3.2.1. Variabel ............................................................................... 36

3.2.2. Definisi Operasional ............................................................ 36

3.3. Populasi dan Sampel ...................................................................... 38

3.3.1. Populasi ................................................................................ 38

3.3.2. Sampel .................................................................................. 38

3.3.3. Teknik Sampling .................................................................. 39

3.3.4. Besar sampel ..................................................................... 39

3.4. Instrument dan Bahan Penelitian ................................................... 40

3.5. Cara Penelitian ............................................................................... 44

3.6. Tempat dan Waktu Penelitian ....................................................... 45

3.7. Analisis Hasil ................................................................................. 45

3.7.1. Cleaning .............................................................................. 45

3.7.2. Editing ................................................................................. 45

3.7.3. Coding ................................................................................. 45

3.7.4. Entry .................................................................................... 46

3.7.5. Analisis Univariat ................................................................ 46

3.7.6. Analisis Bivariat .................................................................. 46

BAB IV HASIL PENELITIAN DAN PEMBAHASAN .................................... 47

4.1. Hasil Penelitian .............................................................................. 47

4.1.1. Analisis Univariat ................................................................ 47

4.1.2. Analisis Bivariat ................................................................... 52

4.2. Pembahasan ................................................................................... 54

ix

4.2.1. Hubungan Tingkat Pengetahuan terhadap Pemeriksaan Pap

smear .................................................................................... 54

4.2.2. Hubungan Sikap terhadap Pemeriksaan Pap smear ............ 55

BAB V KESIMPULAN DAN SARAN ............................................................ 60

5.1. Kesimpulan .................................................................................... 60

5.2. Saran .............................................................................................. 61

DAFTAR PUSTAKA ........................................................................................... 62

LAMPIRAN .......................................................................................................... 65

x

DAFTAR GAMBAR

Gambar 2.1 Anatomi Saluran Reproduksi Wanita ................................................ 7

Gambar 2.2 Organisasi Genom HPV Tipe 16 ....................................................... 9

Gambar 2.3 Interpretasi pemeriksaan pap smear ................................................ 20

xi

DAFTAR TABEL

Tabel 4. 1 Distribusi Responden Berdasarkan Karakteristik Ibu Melakukan

Pemeriksaan Pap smear di RSUD Kraton Pekalongan Tahun 2017 .. 47

Tabel 4. 2 Distribusi Responden Berdasarkan Pernyataan tentang Tingkat

Pengetahuan Ibu terhadap Pemeriksaan Pap smear di RSUD

Kraton Pekalongan Tahun 2017 .......................................................... 48

Tabel 4. 3 Distribusi Responden Berdasarkan Tingkat Pengetahuan Ibu

Melakukan Pemeriksaan Pap smear di RSUD Kraton Pekalongan

Tahun 2017 .......................................................................................... 50

Tabel 4. 4 Distribusi Responden Berdasarkan Pernyataan Sikap Ibu

Melakukan Pemeriksaan Pap smear di RSUD Kraton Pekalongan

Tahun 2017 .......................................................................................... 51

Tabel 4. 5 Distribusi Responden Berdasarkan Sikap Ibu Melakukan

Pemeriksaan Pap smear di RSUD Kraton Pekalongan Tahun 2017 .. 52

Tabel 4. 6 Hubungan Tingkat pengetahuan dan Sikap Ibu terhadap

Pemeriksaan Pap smear di RSUD Kraton Pekalongan Tahun 2017 .. 52

xii

DAFTAR LAMPIRAN

Lampiran 1 Inform Consent Penelitian ............................................................. 65

Lampiran 2 Kuesioner ....................................................................................... 66

Lampiran 3 Uji Validitas dan Realibilitas Kuesioner Penelitian ...................... 69

Lampiran 4 Tabel Variabel ............................................................................... 72

Lampiran 5 Hasil Univariat Distribusi Karakteristik Responden ..................... 80

Lampiran 6 Hasil Univariat Tingkat Pengetahuan ............................................ 81

Lampiran 7 Hasil Univariat Sikap .................................................................... 84

Lampiran 8 Hasil Bivariat Uji Chi Square Pengetahuan .................................. 86

Lampiran 9 Hasil Bivariat Uji Chi Square Sikap ............................................. 88

Lampiran 10 Hasil Correlations Pengetahuan dan Sikap ................................... 89

Lampiran 11 Surat Keterangan ........................................................................... 90

Lampiran 12 Ethical Clearance .......................................................................... 91

Lampiran 13 Dokumentasi Penelitian ................................................................. 92