GGGNNNIIIPPPSSSTTT BBBUUULLLLLLEEETTTIIINNN 222000111555 03rd April, 2015 Volume No.: 44 Issue No.: 01
TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE
BASED LEARNING AND PRACTICE
Contents Message from PRINCIPAL Editorial board Historical article News Update Knowledge based Article Disease Related Breaking
News Upcoming Events Drugs Update Campus News Students Section Editors Note Archive
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GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY
W e bs i t e : ht t p: / / gni ps t. a c. i n
MESSAGE FROM PRINCIPAL
"It can happen. It does happen. But it can't happen if you quit." Lauren Dane.
We are what we repeatedly do. Excellence then is not an act, but a habit. Aristotle
It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the last years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academic excellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners are supported in maximizing their potential and talents. Education needs to focus on personalized learning and instruction, while promoting an education system that is impartial, universally accessible, and meeting the needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order to achieve their aims. We are all very proud of you, our students, and your accomplishments and look forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looking forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in this direction and fruits of these efforts will be received by our students in the near future. Our Teachers are committed and dedicated for the development of the institution by imparting their knowledge and play the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on this path.
My best wishes to all.
Dr. A. Sengupta
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CHIEF EDITOR DR. ABHIJIT SENGUPTA EDITOR MS. JEENATARA BEGUM ASSOCIATE EDITOR MR. DIPANJAN MANDAL
HISTORICAL ARTICLE The Pharmacopeia Comes of Age: The first "United States Pharmacopoeia" (1820) was the work of the medical profession. It was the first book of drug standards from a professional source to have achieved a nation's acceptance. In 1877, the "U.S.P." was in danger of dissolution due to the lack of interest of the medical profession. Dr. Edward R. Squibb, manufacturing pharmacist as well as physician, took the problem to The American Pharmaceutical Association convention. Pharmacists formed a "Committee on Revision" chairmanned by hospital pharmacist Charles Rice, assisted by pharmacist-educator Joseph P. Remington, and by Dr. Squibb, their indefatigable collaborator. The "U.S. Pharmacopoeia" surged to new importance. NEWS UPDATE
World Autism Awareness day: (02nd April) World Autism Awareness Day is observed on 2 April every year since 2008. It was designated by the United Nations General Assembly resolution "62/139. World Autism Awareness Day"; adopted on 18 December 2007, it was proposed by Qatar, and supported by all member states.
One dollar blood test using gold nanoparticles outperforms PSA screen for prostate cancer, study suggests: (03rd April, 2015) A test that uses gold nanoparticles to detect early-stage prostate cancer costs less than $1, returns results in minutes and is more accurate than standard PSA screening, pilot studies show. The
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new technique leverages the ability of gold nanoparticles to attract cancer biomarkers.
Ebola virus diagnostic tool developed by physician who worked in Liberia: (03rd April, 2015) An emergency medicine physician who treated Ebola-infected patients in Liberia last year used his field experience to create a tool to determine the likelihood that patients presenting with Ebola symptoms will actually carry the virus. Ebola Virus Disease (EVD) has affected 24,000 persons during the current epidemic, which is the largest recorded outbreak of EVD in history. Over 10,000 people have died in West Africa, mainly in Sierra Leone, Liberia and Guinea.
Possible progress against Parkinson's and good news for stem cell therapies: (03rd April, 2015) Researchers have taken an important step toward using the implantation of stem cell-generated neurons as a treatment for Parkinson's disease. Using an FDA approved substance for treating cancer, they were able to grow dopamine-producing neurons derived from embryonic stem cells that remained healthy and functional for as long as 15 months after implantation into mice, restoring motor function without forming tumors.
Cancer genes turned off in deadly brain cancer: (03rd April, 2015) Scientists have identified a small RNA molecule that can suppress cancer-causing genes in mice with glioblastoma mulitforme, a deadly and incurable type of brain tumor. While standard chemotherapy drugs damage DNA to stop cancer cells from reproducing, the new method stops the source that creates those cancer cells. The approach could also potentially be used for gene silencing in other cancers and diseases of genetic origin.
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Herpesvirus activates RIG-I receptor to evade body's immune system: (02nd April, 2015) Using herpesvirus, molecular immunologists have discovered a cellular process that activates a critical immune defense against pathogens, which could have implications for developing drugs to bolster one's immunity to infection. Some herpesvirus infections lead to cancer.
Hormone, bone tests may be indicative of dialysis patients' heart health: (02nd April, 2015) Approximately 2 million kidney disease patients in the world receive some sort of dialysis treatment. Now researchers say that in these patients, high parathyroid hormone levels and subsequent bone loss are major risk factors for worsening of coronary artery calcification.
DNA can't explain all inherited biological traits, research shows: (02nd April, 2015) Characteristics passed between generations are not decided solely by DNA, but can be brought about by other material in cells, new research shows. Scientists studied proteins found in cells, known as histones, which are not part of the genetic code, but act as spools around which DNA is wound. Histones are known to control whether or not genes are switched on. For detail mail to editor
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KNOWLEDGE BASED ARTICLE The Tuskegee Syphilis Experiment
For forty years between 1932 and 1972, the U.S. Public Health Service (PHS) conducted an experiment on 399 black men in the late stages of syphilis. These men, for the most part illiterate sharecroppers from one of the poorest counties in Alabama, were never told what disease they were suffering from or of its seriousness. Informed that they were being treated for bad blood, their doctors had no intention of curing them of syphilis at all. The data for the experiment was to be collected from autopsies of the men, and they were thus deliberately left to degenerate under the ravages of tertiary syphiliswhich can include tumors, heart disease, paralysis, blindness, insanity, and death. As I see it, one of the doctors involved explained, we have no further interest in these patients until they die.
Using Human Beings as Laboratory Animals The true nature of the experiment had to be kept from the subjects to ensure their cooperation. The sharecroppers' grossly disadvantaged lot in life made them easy to manipulate. Pleased at the prospect of free medical carealmost none of them had ever seen a doctor beforethese unsophisticated and trusting men became the pawns in what James Jones, author of the excellent history on the subject, Bad Blood, identified as the longest non therapeutic experiment on human beings in medical history. The study was meant to discover how syphilis affected blacks as opposed to whitesthe theory being that whites experienced more neurological complications from syphilis whereas blacks were more susceptible to cardiovascular damage. How this knowledge would have changed clinical treatment of syphilis is uncertain. Although the PHS touted the study as one of great scientific merit, from the outset its actual benefits were hazy. It took almost forty years before someone involved in the study took a hard and honest look at the end results, reporting that nothing learned will prevent, find, or cure a single case of infectious
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