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GNIPST Bulletin 43.4

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GNIPST Bulletin 43.4

Text of GNIPST Bulletin 43.4

  • 27-03-2015

    GGGNNNIIIPPPSSSTTT BBBUUULLLLLLEEETTTIIINNN 222000111555 27th March, 2015 Volume No.: 43 Issue No.: 04




    Contents Message from PRINCIPAL Editorial board Historical article News Update Knowledge based Article Disease Related Breaking

    News Upcoming Events Drugs Update Campus News Students Section Editors Note Archive

    GNIPST Photo Gallery For your comments/contribution OR For Back-Issues, mailto:[email protected]


    W e bs i t e : ht t p: / / gni ps t. a c. i n[email protected]

  • 27-03-2015


    "It can happen. It does happen. But it can't happen if you quit." Lauren Dane.

    We are what we repeatedly do. Excellence then is not an act, but a habit. Aristotle

    It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the last years editors and congratulate the newly selected editors for the current year.

    Our first consideration is always in the best interest of the students. Our goal is to promote academic excellence and continuous improvement.

    I believe that excellence in education is aided by creating a learning environment in which all learners are supported in maximizing their potential and talents. Education needs to focus on personalized learning and instruction, while promoting an education system that is impartial, universally accessible, and meeting the needs of all students.

    It is of paramount importance that our learners have sufficient motivation and encouragement in order to achieve their aims. We are all very proud of you, our students, and your accomplishments and look forward to watching as you put your mark on the profession in the years ahead.

    The call of the time is to progress, not merely to move ahead. Our progressive Management is looking forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in this direction and fruits of these efforts will be received by our students in the near future. Our Teachers are committed and dedicated for the development of the institution by imparting their knowledge and play the role of facilitator as well as role model to our students.

    The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic needs of our students.

    I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the opportunities and meet the challenges with purpose and determination.

    Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on this path.

    My best wishes to all.

    Dr. A. Sengupta

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  • 27-03-2015



    HISTORICAL ARTICLE A Revolution in Pharmaceutical Education: When Dr. Albert B. Prescott launched the pharmacy course at the University of Michigan in 1868, critical attention was aroused because he abandoned the traditional requirement of pregraduation apprenticeship. At the 1871 convention of the American Pharmaceutical Association, he was denied credentials and ostracized. However, the Michigan course pioneered other major changes: laboratory pharmacy, a definite curriculum that included basic sciences, and a program that demanded students' full-time attention. During the next thirty years, Dr. Prescott had the satisfaction of seeing his once revolutionary innovations generally adopted by pharmaceutical faculties. NEWS UPDATE

    Long-standing mystery in membrane traffic solved: (27th March, 2015) In 2013, James E. Rothman, Randy W. Schekman, and Thomas C. Sdhof won the Nobel Prize in Physiology or Medicine for their discoveries of molecular machineries for vesicle trafficking, a major transport system in cells for maintaining cellular processes. SNARE proteins are known as the minimal machinery for membrane fusion. Scientists now report that NSF/?-SNAP disassemble a single SNARE complex using various single-molecule biophysical methods that allow them to monitor and manipulate individual protein complexes.

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  • 27-03-2015

    More than one-third of Division I college athletes may have low vitamin D levels: (27th March, 2015) A new study found that more than one-third of elite, Division I college athletes may have low levels of vitamin D, which is critical in helping the body to absorb calcium needed to maintain bone mass, and to minimize musculoskeletal pain and injury risk.

    How body's good fat tissue communicates with brain: (27th March, 2015) Brown fat tissue, the bodys good fat, communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat weve lost, according to researchers.

    Bio-marker set forms the basis for new blood test to detect colorectal cancer: (27th March, 2015) Colorectal cancer is the third most common form of cancer globally and the second most common cause of cancer deaths. The chance of a cure is high if the cancer is detected early enough, but early detection is not a given. Researchers have identified bio-markers that can be incorporated in a new diagnostic test. This should make it possible to detect colorectal cancer in an early stage using a simple blood test, they say.

    Big data allows computer engineers to find genetic clues in humans: (27th March, 2015) Computer scientists tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.

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  • 27-03-2015

    MRI based on a sugar molecule can tell cancerous from noncancerous cells: (27th March, 2015) Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn't cancer usually requires a biopsy to study cells directly. Now results of a study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.

    First fully-implantable micropacemaker designed for fetal use: (26th March, 2015) The first fully implantable micropacemaker designed for use in a fetus with complete heart block has been designed by researchers. The investigators anticipate the first human use of the device in the near future.

    A possible novel therapy for a rare but potentially fatal blood disorder: (26th March, 2015) A transgenic mouse model is a proof-of-concept that platelet blood cells that are loaded with the enzyme ADAMTS13 can be an effective treatment in murine models of thrombotic thrombocytopenic purpura.

    Genetic mutation helps explain why, in rare cases, flu can kill: (26th March, 2015) A small number of children who catch the influenza virus fall so ill they end up in the hospital even while their family and friends recover easily. New research helps explain why: a rare genetic mutation that prevents the production of a critical protein, interferon, that is needed to fight off the virus.

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  • 27-03-2015

    Antibiotic effectiveness imperiled as use in livestock expected to increase: (26th March, 2015) Antibiotic consumption in livestock worldwide could rise by 67 percent between 2010 and 2030, and possibly endanger the effectiveness of antimicrobials in humans, researchers warn.

    Longevity: Role of genes is greater with living to older ages: (26th March, 2015) Genes appear to play a stronger role in longevity in people living to extreme older ages, according to a study of siblings.

    To survive, a parasite mixes and matches its disguises, study suggests: (26th March, 2015) Researchers found an unexpected diversity of protein coats within populations of Trypanosoma brucei, challenging the conventional understanding of the dynamics that allow the parasite to persist. Orchestrated costume changes make it possible for certain nasty microbes to outsmart the immune system, which would otherwise recognize them by the telltale proteins they wear, the researchers explain. For detail mail to editor

    KNOWLEDGE BASED ARTICLE Taste of Raspberries, Taste of Death The 1937 Elixir Sulfanilamide Incident

    By the 1930s it was widely recognized that the Food and Drugs Act of 1906 was obsolete, but bitter disagreement arose as to what should replace it. By 1937 most of the arguments had been resolved but Congressional action was stalled. Then came a shocking development, the deaths of more than 100 people after using a drug that was clearly unsafe. The incident hastened final enactment in 1938 of the Federal Food, Drug, and Cosmetic Act.

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    mailto:[email protected]

  • 27-03-2015

    Dr. Calhoun's patients was killed by Elixir Sulfanilamide. During September and October 1937 this drug was responsible for the deaths of more than 100 p