GNIPST Bulletin 37.3

8/11/2019 GNIPST Bulletin 37.3

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12th

September, 2014 Volume No.: 37 Issue No.: 03

Vision

TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BAS

LEARNING AND PRACTICE

ontentsMessage from PRINCIPAL

Editorial board

Historical article

News Update

Knowledge based Article

Disease Related Breaking

News

Upcoming Events

Drugs Update

Campus NewsStudents Section

Editors Note

Archive

GNIPST Photo Gallery

or your comments/contribution

For ack-Issues,

ailto:[email protected]

GURU NANAK INSTITUTE OF PHARMACEUTICAL

SCIENCE AND TECHNOLOGY

Website:http://gnipst.ac.in
https://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7mailto:[email protected]:[email protected]:[email protected]://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7


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MESSAGE FROM PRINCIPAL

"It can happen. It does happen.But it can't happen if you quit." Lauren Dane.

We are what we repeatedly do.

Excellence then is not an act, but a habit. Aristotle

It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank tlast years editors and congratulate the newly selected editors for the current year.

Our first consideration is always in the best interest of the students. Our goal is to promote academexcellence and continuous improvement.

I believe that excellence in education is aided by creating a learning environment in which all learners a

supported in maximizing their potential and talents. Education needs to focus on personalized learni

and instruction, while promoting an education system that is impartial, universally accessible, and meetithe needs of all students.

It is of paramount importance that our learners have sufficient motivation and encouragement in order achieve their aims. We are all very proud of you, our students, and your accomplishments and loo

forward to watching as you put your mark on the profession in the years ahead.

The call of the time is to progress, not merely to move ahead. Our progressive Management is looki

forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken

this direction and fruits of these efforts will be received by our students in the near future. Our Teacheare committed and dedicated for the development of the institution by imparting their knowledge and pl

the role of facilitator as well as role model to our students.

The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positi

challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holist

needs of our students.

I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of t

opportunities and meet the challenges with purpose and determination.

Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us this path.

My best wishes to all.

Dr. A. Sengupta

Click here to go at the top

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EDITORIAL BOARD

CHIEF EDITOR DR. ABHIJIT SENGUPTA

EDITOR MS. JEENATARA BEGUM

ASSOCIATE EDITOR MR. DIPANJAN MANDAL

HISTORICAL ARTICLE

Galen Experimenter in Drug Compounding:Of the men of ancient times whose names are known and revered

among both the professions of Pharmacy and Medicine, Galen,

undoubtedly, is the foremost. Galen (130-200 A.D.) practiced and

taught both Pharmacy and Medicine in Rome; his principles ofpreparing and compounding medicines ruled in the Western

world for 1,500 years; and his name still is associated with that

class of pharmaceuticals compounded by mechanical means -

galenicals. He was the originator of the formula for a cold cream,

essentially similar to that known today. Many procedures Galen

originated have their counterparts in today's modern

compounding laboratories.

NEWS UPDATE

International Literacy Day: (8th September,

2014)The theme of International Literacy Day 2014 is Literacy and

Sustainable Development.

Nicotine withdrawal reduces response to rewardsacross species: (12thSeptember, 2014)While more than half of US smokers try to quit every year, lessthan 10 percent are able to remain smoke-free, and relapsecommonly occurs within 48 hours of smoking cessation. In a first


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of its kind study on nicotine addiction, scientists measured abehavior that can be similarly quantified across species likehumans and rats, the responses to rewards during nicotinewithdrawal. Learning about withdrawal and difficulty of quitting

can lead to more effective treatments to help smokers quit.From worm muscle to spinal discs: An

evolutionary surprise: (12thSeptember, 2014)Thoughts of the family tree may not be uppermost in the mind of aperson suffering from a slipped disc, but those spinal discs providea window into our evolutionary past. They are remnants of thefirst vertebrate skeleton, whose origins now appear to be olderthan had been assumed. Scientists have found that, unexpectedly,this skeleton most likely evolved from a muscle.

One-minute point-of-care anemia test shows

promise in new study: (12thSeptember, 2014)A simple point-of-care testing device for anemia could providemore rapid diagnosis of the common blood disorder and allowinexpensive at-home self-monitoring of persons with chronicforms of the disease. About a third of the population is at risk for

anemia, which can cause neurocognitive deficits in children, organfailure and less serious effects such as chronic fatigue. Women,children, the elderly and those with chronic conditions such askidney disease are more likely to suffer from anemia.

Combining gut hormone with insulin proves more

effective at controlling type 2 diabetes than

other common treatments: (11th September,

2014)Combined treatment with a drug that mimics the action of a guthormone and basal insulin is more effective at improving bloodsugar control than other anti-diabetic treatments, with similarrates of hypoglycaemia (dangerously low blood sugar levels) andgreater weight loss, a systematic review and meta-analysis shows.


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Faster way found to create insulin-producing

cells: (11thSeptember, 2014)A study highlighting a protocol to convert stem cells into insulin-

producing cells has been published by researchers. The newprocedure could be an important step in the fight against type 1diabetes. The protocol can turn stem cells into reliable, insulin-producing cells in about six weeks, far quicker than the fourmonths it took using previous methods.

Tipping the balance of behavior: Neurons found

that control social behavior may have

implications for autism: (11

th

September, 2014)Antagonistic neuron populations in the mouse amygdala thatcontrol whether the animal engages in social behaviors or asocialrepetitive self-grooming have been recently discovered byresearchers. Dubbed a 'seesaw circuit,' this discovery may haveimplications for understanding neural circuit dysfunctions thatunderlie autism in humans.

Inflammation may be key to diabetes-heart

disease link: (11th

September, 2014)Inflammation may be the reason high blood sugar levels damageblood vessels, researchers report. Anti-inflammatory medicationsmight someday be used to reduce the risk of blood vessel disease inpeople with diabetes, they say.

Simple method turns human skin cells into

immune strengthening white blood cells: (11th

September, 2014)For the first time, scientists have turned human skin cells intotransplantable white blood cells, soldiers of the immune systemthat fight infections and invaders. The work could let researcherscreate therapies that introduce into the body new white blood


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cells capable of attacking diseased or cancerous cells oraugmenting immune responses against other disorders.

New genetic targets discovered in fight against

muscle-wasting disease: (11th

September, 2014)Findings of a new study offer the possibility of developing newways of tackling an incurable condition known as muscle-wastingdisease. To date, only six genes have been linked to the illness.Despite rigorous screening, at least 50% of patients have nodetectable mutation in the 6 known genes. Now a breakthroughstudy has discovered two more genes linked to the disease.

Malaria parasites sense and react to mosquito

presence to increase transmission: (11thSeptember, 2014)Many pathogens are transmitted by insect bites. The abundance ofvectors (as the transmitting insects are called) depends onseasonal and other environmental fluctuations. A new articledemonstrates that Plasmodium parasites react to mosquitoesbiting their hosts, and that the parasite responses increasetransmission to the mosquito vector.

Ebola paper demonstrates disease transmissionrate: (11thSeptember, 2014)Transmission rates for each single case of Ebola consistentlyshowed at least one new case of the disease being transmitted.Country-specific analysis of transmission rates in Liberia andSierra Leone showed on average between one and two new casesfor every existing case, research has shown.

Cells put off protein production during times ofstress: (11thSeptember, 2014)When a stressed cell recognizes the buildup of misfolded proteins,it responds by reshuffling its workload, much like a stressed outemployee might temporarily move papers from an overflowinginbox into a junk drawer. The study could lend insight into


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misfolded protein diseases such as Alzheimer's, ALS, Huntington's,Parkinson's, and type 2 diabetes.

For detail mail toeditor

KNOWLEDGE BASED ARTICLE

Structural States of a Brain Receptor Revealed

Receptors are present on the cell surface serve as keepers whichtransmit signals from inside to the outside. Glutamate receptorsare present on the nerve cells that span the cell membrane. Theglutamate comes in contact with the receptors present on outside,

the receptors change within seconds and opens up withinmilliseconds. This allows small substances like ions to enter thecell.

The process is crucial for communication between the nerve cellsand plays a important role in the development of the brain,learning and memory. The problems associated with the glutamatereceptor functioning are thought to be involved in numerousdisorders including autism, schizophrenia, depression, Parkinsons

disease and some types of cancer.

As reported by Dr. Sriram Subramanian of NIHs National cancerInstitute (NCI) in collaboration with Eunice Kennedy ShriverNational Institute of Child Health and Human Development(NICHD) and others, set out to determine the structure of theGlutamate receptor as it transitions from its resting state to opento Desensitized (reduced response to glutamate) states.


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Structure of the glutamate receptor,Showing the part where glutamate Bindsoutside the cell and the part that Spans the cell membrane (between the Dottedlines)

A structure of one glutamate receptor variant in its resting state

had previously been determined by using X-ray crystallography.This technique requires a protein to first be crystallized into afixed 3-D shape. However, capturing the proteins multiple statesin a crystal is challenging, and could potentially trap subtlymisfolded or incorrect structures.In findings that appeared online on August 3, 2014, in Nature, theteam used an imaging technique called cryo-electron microscopy.This method allowed them to capture high-resolution snapshots ofreceptors in several transitional stages.The group analyzed detailed images of different types of glutamatereceptors and captured the receptors in different states. Theydetermined that the transition of the protein from the resting toopen states involved a corkscrew-like rotational motion within theprotein.


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The shift from open to desensitized states required much largerrearrangements.The scientists note that while several technical hurdles remain, thetechnique will allow them to analyze the structures of many other

proteins, as well as study receptor-drug interactions.Anurag Chanda

Student, GNIPST

B.Pharm, 4thYear

DISEASE RELATED BREAKING NEWS

Ebola virus disease: (10thSeptember, 2014)

Between 2 and 9 September 2014, there have been 31 more cases ofEbola virus disease (EVD) reported in the Democratic Republic of

the Congo (DRC), increasing the cumulative number of cases to 62

(14 confirmed, 26 probable, and 22 suspect). In total, 35 deaths

have been reported (9 confirmed and 26 probable).Read more

UPCOMING EVENTS

5

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International Conference on Stem Cells and Cancer 2014, JNUConvention Centre, New Delhi, India from 8-10 November, 2014

DRUGS UPDATES

FDA Approves New Obesity Drug Contrave: (11th

September, 2014)The U.S. Food and Drug Administration's approval of a new

weight-loss drug marks the third time the agency has given itsblessing to a new diet medication since 2012. Called Contrave, themedicine is a combination of two approved drugs: naltrexone,which treats alcohol and drug addiction, and bupropion, whichtreats depression and seasonal affective disorder and is used tohelp smokers quit.Read more


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http://www.who.int/csr/don/2014_09_10_ebola/en/http://www.who.int/csr/don/2014_09_10_ebola/en/http://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.who.int/csr/don/2014_09_10_ebola/en/


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CAMPUS NEWS

Today, on 5th September, 2014 the students of GNIPST have

arranged a wonderful Teachers Day Programme. On behalf of allthe teachers of GNIPST I would like to thank our beloved

students.

The Freshers welcome programme was held on 14thAugust, 2014.Welcome 1styear students.

We congratulate the following M.Pharm. final year students whohave made their positions in different pharmaceutical companies.

Anirban Banerjee (Emami Ltd.)Mahender Roy (Stadmed private Ltd.)

We congratulate the following B.Pharm. final year students fortheir success.

Samadrita Mukherjee (Abbott India Ltd.)

Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)

Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)

Avishek Naskar (Glaxo SmithKline-Marketing)Bappaditya Manik (USV Limited)

Sarbani Das (Nutri Synapzz-Marketing)

Ankita Roy (Nutri Synapzz-Marketing)

Rahul Mitra (B M Pharmaceuticals-Production)

The following B.Pharm. final year students have qualified, GPAT-2014. We congratulate them all.

Utsha Sinha

Satarupa Bhattacharya

Sandipan Sarkar

Purbali Chakraborty

Reminiscence, 2014(GNIPST Reunion) was held in Collegecampus on 2ndFebruary,2014.


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1st Annual Sports of GNIPST was held on 3rd February,2014 inCollege campus ground.

An industrial tour and biodiversity tour was conducted in Sikkim

for B.Pharm and B.Sc. students under the supervision of Mr. AsisBala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.

B.Pharm 3rd year won the GNIPST Football Champions trophy,2013. B.Pharm 3rdyear won the final match 1-0 against B.Pharm 2nd

year. Deep Chakrabortywas the only scorer of the final.

STUDENTS SECTION

WHO CAN ANSWER FIRST????

Story of my life published in 1903 is the

autobiography of which famous

personality?

Who is the first Arjuna awardee in

cricket?

Answer of Previous Issues Questions

A) 5th October

B) 1962


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Identify the lady

Answer of Previous Issues Image

Anne Sulivan

Send your thoughts/

Quiz/Puzzles/games/write-ups or any other

contributions for Students Section

answ ers of this Section at [email protected]

EDITORS NOTE

It is a great pleasure for me to publish the 3rd

issue of 37th

Volume

of GNIPST BULLETIN. All the followers of GNIPST BULLETINare able to avail the bulletin through facebook account GNIPST

bulletin I am very much thankful to all the GNIPST members and

readers who are giving their valuable comments, encouragements

and supports. I am also thankful to Dr. Abhijit Sengupta, Director

of GNIPST for his valuable advice and encouragement. Special

thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar

and Mr. Soumya Bhattacharya for their kind co-operation and

technical supports. Thank you Mr. Soumya Bhattacharyafor the

questionnaires of the student section. An important part of the

improvement of the bulletin is the contribution of the readers. You

are invited to send in your write ups, notes, critiques or any kind of

contribution for the forthcoming special and regular issue.


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ARCHIVE

Students of GNIPST organized pre puja celebration programme,Saaranya on 7thOctober, 2013 in college Auditorium.

GNIPST organized a garment distribution programme on 28thSeptember, 2013 at Dakshineswar Kali Temple and Adyapith,

Kolkata. On this remarkable event about hundred people have

received garments. More than hundred students and most of the

faculties participated on that day with lot of enthusiasm.

GNIPST celebrated World Heart Day (29th

September) andPharmacists Day (25thSeptember)on 25thand 26thSeptember,

2013 in GNIPST Auditorium. A seminar on Violence against

woman and female foeticide was held on GNIPST Auditorium on

25th September organized by JABALA Action Research

Organization. On 26thSeptember an intra-college Oral and Poster

presentation competition related to World Pharmacists day and

Heart day was held in GNIPST. Ms. Purbali Chakraborty ofB.Pharm 4th year won the first prize in Oral Presentation. The

winner of Poster presentation was the group of Ms. Utsa Sinha,

Mr. Koushik Saha and Mr. Niladri Banerjee(B.Pharm 4thyear). A

good number of students have participated in both the

competition with their valuable views.

Teachers daywas celebrated on 5thSeptember, 2013 by the

students of GNIPST in GNIPST Auditorium.

Azalea exotic flower ) , the fresher welcome programme for

newcomers of GNIPST in the session 2013-14 was held on 8th

August in GNIPST Auditorium.


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One day seminar cum teachers development programme forschool teachers on the theme of Recent Trends of Life Sciences

in Higher Education organized by GNIPST held on 29th June,

2013 at GNIPST auditorium. The programme was inaugurated byProf . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy

Director of JIS Group and Dr. Abhijit Sengupta, Director cum

Principal of GNIPST with lamp lighting. The programme started

with an opening song performed by the B.Pharm students of this

institute. The seminar consists of a series of lectures, video

presentations and poster session. On the pre lunch session 4

lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata

Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty

respectively. On their presentation the speakers enlighten the

recent development of Pharmacy, Genetics and Microbiology and

their correlation with Life Sciences. On the post lunch session, Ms.

Saini Setua and Ms. Sanchari Bhattacharjee explained the recent

development and career opportunities in Biotechnology and

Hospital Management. The programme was concluded with

valedictory session and certificate distribution.About 50 Higher secondary school teachers from different

schools of Kolkata and North& South 24 Parganas district of West

Bengal participated in this programme. A good interactive session

between participants and speakers was observed in the seminar.

The seminar was a great success with the effort of faculties, staffs

and students of our Institute. It was a unique discussion platform

for school teachers and professional of the emerging and newerbranches of Life Science.

The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15thJune, 2012. The program started with

a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural


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Products, JU on the skill to write a good manuscript for

publication in impact journals. It was followed by nearly two hour

long discussion among more than thirty participants on different

aspects of pharmacy education. Five nonmember participants

applied for membership on that very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm)

in P H A R M A C O L O G Y .The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to

120.

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-13to

GNIPST as per the details below:

a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical

Science & Technology.

b.Principal Investigator:Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- onlyd.Approved duration: 3 years

e. Title of the project: Screening and identification of potential

medicinal plant of Purulia & Bankura districts of West Bengal

with respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.


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Documents

GNIPST Bulletin 37.3