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Gut structure
• Mucosa• Submucosa• Muscularis externa• Serosa
• Regarding the PH range is as the following
• A) For buccal cavity the PH is approximately 7• B) Esophagus PH is 5-6• C) Stomach PH is 1-3, decomposition of some drugs occurs here
& weak acids are un-ionized• D) Duodenum PH is 6-6.5 contains ducts & surfactant properties• E) Small Intestine PH is around 7-8• F) Large Intestine PH is about 5.5-7
pH of the Gastrointestinal Contents of Various Species∗
Regarding the Surface Area
A)Buccal cavity, esophagus & stomach have a small
surface area
B) Duodenum have a very large surface area
C) Small intestine have a very large 10-14 ft
D) The large intestine doesn’t have very large area,
about 4-5 ft
Regarding the Transit Time
A) Buccal Cavity have a short unless controlled timeB) Esophagus have a short timeC) Stomach have 30-40 minutes (small time) with reduced absorptionD) Duodenum have a very short window effectE) The small intestine have about 3 hoursF) The large intestines have a long one up to 24 hours
Regarding the Transit Time
A) Buccal Cavity have a short unless controlled timeB) Esophagus have a short timeC) Stomach have 30-40 minutes (small time) with reduced absorptionD) Duodenum have a very short window effectE) The small intestine have about 3 hoursF) The large intestines have a long one up to 24 hours