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ANTIAGING WITH STEM CELLS AND HOLISTIC APPROACH Dr Pradeep Mahajan

Antiaging with Stem Cell & Holistic Approach

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ANTIAGING WITH STEM CELLS AND HOLISTIC APPROACH

ANTIAGING WITH STEM CELLS AND HOLISTIC APPROACHDr Pradeep Mahajan

THE AGING MYTHOur lives are a giant forest, and the second we're born a fire is set to it. During our lives we can do things to FAN those flames (like by not eating right, abusing drugs, etc) and burn the forest down faster.We can also do things to SLOW it down, too.But you can't douse that fire totallyIt ALWAYS burns.And eventually, ALL our forests burn down.

We may already be too late, Mr. Parker.

Aging is the Largest KillerIn India 1 in 25 will be a senior citizen in 2020This ratio is several times higher in the Western countriesWith state of the art technologies we can now evaluate the status of aging in the body and monitor it.We also have technologies that can reduce the rate of aging at the cellular and molecular levelThis is evidenced by improvement in all the Physiological, Biochemical and Molecular parameters of Aging

So...what is 'aging', exactly?Aging is:

The life-long accumulation of damage to the tissues, cells, and molecules of the body that occurs as an intrinsic side-effect of the body's normal operation.

The body can tolerate some damage, but too much of it causes disease and disability.

Aging / SenescesAging process involves progressive cellular depletion of stem cells, so the body's vitality and reserve capacity also diminishes. Hence the introduction of new stem cells offers the potential of slowing down, or reversing, this degenerative process.

Genetics of Aging:

Aging is not a passive activity, But an actively regulated metabolic process

Specific genes identified that regulate aging, Aging and Longevity are only partially under genetic influenceRest of Gain is from Nutrition

It is possible to increase life span by environmental modification; caloric restriction can increase life spandysregulation of glucose homeostasis is a hallmark of aging in humanstype 2 diabetes, a disease of glucose homeostasis, is a form of accelerated agingAging and Diabetes are both common risk factors for a wide range of diseasesAging and Diabetes are related at a molecular level

Average lifespan with Aging diseases

The Future of Living Well to 100Healthy aging presents an enormous challengeAdvances in biological sciences provide the knowledge and tools needed tounderstand nutrition at genetic and molecular levels andelevate the scientific basis underlying nutritional recommendationsUnderstanding roles requires interdisciplinary cooperation of:nutritiongenetics, inflammationDeveloping partnerships among specialties to promote the goal of healthy agingcome together as a science communitygenerate the evidence base to influence recommendationsValue of nutrition and genetics in achieving healthy aging

Am. J. Clinical Nutrition, Feb 2006; 83: 488s - 490s. Gordon W Duff, Peter Libby, Jos M Ordovas, and Philip R Reilly

The Different Paths to 100 Most centenarians do not have significant disability90% of centenarians functionally independent @ ave. age of 92 yearsA more enabling point of view emerges to achieve extreme old age :The older an individual gets, the healthier he or she has beenCentenarians showRelative resistance to age-related diseases Slower aging

Where are we heading1 centenarian per 10,000 persons in the United States NOW1 centenarian per 5,000 persons for industrialized nations SOONAbility to survive to extreme old age appears to be the result of:Complex combination of Genetics, EnvironmentLifestyle (Diet, Exercise, Social Activities), and Luck

The Future Path lies in:Better Perinatal Nutrition = Omega-3, NutrientsGenetics of the Very OldIdentifying the molecular drivers of longevity or mortality = omega 3/6 ratioDiscovering and targeting the pathways mediating aging and disease susceptibilityDeveloping preventive and therapeutic agents that will allow aging in good health

How to Delay, Reverse The Aging?i.e Anti AgingRemove the damage or Inactive molecules and cellsRestore function to several molecules by repair & ReplacementModify the Genetic Program to prevent the aging process from continuing

How are we going to do Above changes...???

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Antiaging Treatment ApproachesSUPERFOODSStem cellsTherapy &Banking

Immuno ModulatorsPrognostic &Diagnostics

Who Can take Anti-Aging TreatmentAbsolutely healthy aging (King of Good Times)Patients with age related diseases (Struggler King)Aging patients with serious & Advanced diseases (Bankrupt King)

Holistic approach to Anti-aging TherapyCongnitive Behavioral Therapy(W C Bushwell 2006)WhatHowEnhancing Self healing capacitiesMobilization of dormant or sleeping stem cellsActivate body immune systemDecreasing Free radicalsLink between nutrition & gene to be establishedtelomers

Diet Veg & Fruits, Green TeaWorkout, Meditation, Breathing Exercises Coping the stressCalorie RestrictionsAntioxidantsGrowth hormone supplements

Congnitive Behavioural TherapyMain action is on bone marrow and pineal glandIncreasing molecular mediators like DHEA, IL4, IL10 & Melatonin & Growth hormonesEnhancing health and anti aging effects using dormant stem cells & immune system

Not only to give more years to life but especially to give more life to years by stem cells therapy

HumanAn Adult Human once a tiny cell, is a self assembling machine made of trillions of microscopic components Roughly a human being consist of ~7 x 1027 atoms and ~5 x 105 molecular genetic particles.Here we see = Gene proteins- an organic nano structure working with molecular precession to form complete cell. At age 30 around 30 million stem cells are in circulation

Types / Sources of stem cells

Stem cells proportion with aging

growing cells > apoptic cells (Child)Growing cells = apoptic cells (Mature person)Growing Cells < apoptic cells (Aging Starts)

Why Stem Cells...Stem cells and biological science is poised to become next revolution in medicine to provide exciting and promising alternatives to most traditional solutions (allopathic), surgery and drugs within the reach of everyday people.Treating Todays medical Problem with tomorrow's solution.

Gene TherapyIf aging may be Reversed by expressing of key genes then gene therapy holds a great future promiseDelivers major information of aging in human bodyInvolves use of vector for specific purpose for inserting DNAs in cells RNAiLimitation:- Small Bandwidth for information

Cell TherapyCell therapy has greater bandwidthCells can be genetically engineered In vitro prior to be used for treatment.

THE ADVANTAGES Of Stem Cell Anti-Aging Treatment

Stem Cells from your own body are usedNo chemicals or drugs are neededBetter breathing and sleeping pattern.Energy levels restoredAge spots fadeComplexion brightens and skin softensNo more expensive supplements or creams requiredHormones are re-balancedSugar levels controlled

Heightened sexual driveIncreased metabolism and surprisingly an average 4-7 kg weight loss.Hair color darkening and volume increasing.There is also a better control of blood pressure and improved visionEmotional and cognitive improvement occurs, memory improves, concentration ability increases and your ability to handle complex tasks, as you did before, is regained.

God SeedChanging the soul of Man...

The God seed will take over the Programmingthe DNA

God Seed

You carry your own natural repairing kits in your own body!www.stemrx.intwitter: @StemRx

Stem cellsGenetic code