Subarachnoid Hemorrhage in Type 1Diabetes

A prospective cohort study of 4,083 patients with diabetes

Featured Article:

Miikka Korja, M.D., P.H.D., Lena M. Thorn, M.D., P.H.D., Stefanie Hägg, M.B.,Jukka Putaala, M.D., P.H.D., Ron Liebkind, M.D., P.H.D., Valma Harjutsalo,

P.H.D., Carol M. Forsblom, P.H.D., Daniel Gordin, M.D., P.H.D., Turgut Tatlisumak, M.D., P.H.D., Per-Henrik Groop, M.D., P.H.D., On Behalf of The

FinnDiane Study Group*

Diabetes Care Volume 36: 3754-3758

November, 2013

STUDY OBJECTIVE 

• To estimate the incidence of subarachnoid hemorrhage (SAH) in type 1 diabetes

Korja M. et al. Diabetes Care 2013;36:3754-3758

STUDY DESIGN AND METHODS

• Incidence of first-ever SAH events was analyzed using the nationwide Finnish Diabetic Nephropathy (FinnDiane) Study cohort

Korja M. et al. Diabetes Care 2013;36:3754-3758

RESULTS

• During the follow-up time of 36,680 person-years, 15 patients experienced an aneurysmal or nonaneurysmal SAH

• Thus, the crude incidence of SAH was 40.9 per 100,000 person-years

• One patient had a verified aneurysmal SAH

• Four patients died suddenly of an SAH, which was most likely caused by an aneurysm

Korja M. et al. Diabetes Care 2013;36:3754-3758

RESULTS

• SAHs in 10 of 15 patients were classified as nonaneurysmal SAH

• Thus, the crude incidence of nonaneurysmal SAH was 27.3 per 100,000 person-years

• None of the nonaneurysmal SAHs were fatal

Korja M. et al. Diabetes Care 2013;36:3754-3758

CONCLUSIONS

• Incidence of nonaneurysmal SAH is high among patients with type 1 diabetes

• Nonaneurysmal SAH is a distinct new microvascular complication in type 1 diabetes

Korja M. et al. Diabetes Care 2013;36:3754-3758

Korja M. et al. Diabetes Care 2013;36:3754-3758

Korja M. et al. Diabetes Care 2013;36:3754-3758

Korja M. et al. Diabetes Care 2013;36:3754-3758