680

Jpn J OphthalmolVol 45: 677–684, 2001

A Clear Cell Type Meningioma in the Upper Eyelid Ascertained by Immunohistochemical Examination

Background:

We encountered a rare case of clearcell meningioma in the upper eyelid.

Case:

A 66-year-old man presented with a slow butprogressive, well-defined, soft globelar tumor in theleft upper eyelid. The tumor showed homogeneousisodensity and contrast in a computed tomograph. His-tologically, oval-shaped cells with clear cytoplasm hadboth streamed and whorl configurations, but showedneither psammomas nor calcification. Immunohis-tochemically, vimentin, epithelial membrane antigen,and protein S-100 were expressed by the tumor cells.

Conclusions:

Eyelid meningioma may originate fromembryonal remains of the arachnoid in the sheatharound the trigeminal nerve, and may vary histologi-cally. Immunohistochemical examination helps todefine cases of uncommon subtypes of meningioma.(J Jpn Ophthalmol Soc 105:343–347, 2001)

Saori Harada*, Daisuke Watanabe*, Hiroyuki Kaneko*, Yuji Nemoto*, Nobue Kubota* and Tetsuo Imamura

†

*Department of Ophthalmology, Teikyo University School of Medicine;

†

Department of Surgical Pathology, Teikyo University School of Medicine

PII S0021-5155(01)00437-3

A Case of Subacute Bacterial Endocarditis Showing Acute Macular Neuroretinopathy-like Lesions

Purpose:

We report one case of mimic fundus lesionswith acute macular neuroretinopathy due to sub-acute bacterial endocarditis.

Case:

A 55-year-old male had about a 1 DD reddishpetal-shaped lesion at the level of the retinal pig-ment epithelium in the macula and a white lesionabout 1/6 DD at the level of the retinal pigment epi-thelium in the upper fovea. Fluorescein angiographyshowed the reddish lesion to be hypofluorescencedue to a filling defect and indocyanine green angiog-raphy showed the hypofluorescence was due to a cir-culatory disturbance of the choriocapillaris. Addi-tionally, we found that there was a severe choroidalcirculatory obstruction in the white lesion on the ret-inal pigment epithelium. After the disappearance ofthe white lesion, secondary retinal pigment epithe-lium atrophy remained.

Conclusion:

The macular lesions of acute macularneuroretinopathy were ischaemic lesions of the reti-nal pigment epithelium formed because of a distur-bance at the level of the choriocapillaris. (J Jpn Oph-thalmol Soc 105:348–352, 2001)

Kazuko Takiura and Mitsuko Yuzawa

Department of Ophthalmology, Surugadai Hospital of Nihon University

PII S0021-5155(01)00438-5

The Present State of Blindness in the World: A Review

Purpose:

To investigate the present state of blind-ness around the world.

Methods:

The article reviews significant studies byWHO and literature on the topic.

Results:

Current global estimates indicate that blind-ness affects close to 45 million people, with 9 out of10 blind people living in developing countries. Two-thirds or more of all blindness is avoidable, in thatthe causes are preventable or treatable. Cataract isthe major cause of blindness in the world and thenumber of cases is increasing. The second cause isglaucoma, and the third is trachoma. The extent ofdisability of blindness itself is very high compared tothat of other illnesses. Also, in terms of the burdenof diseases in society, blindness is a relatively hugeproblem in the developing world.

Conclusions:

Intervention should be focused on thefactors that have the highest possibility of change.Manpower development is the most important coun-termeasure. The aid required to support developingcountries is what can make them stand on their ownin long-term ophthalmic care. (J Jpn OphthalmolSoc 105:369–373, 2001)

Yoshimune Hiratsuka, Koichi Ono and Atsushi Kanai

Department of Ophthalmology, Juntendo University School of Medicine

PII S0021-5155(01)00439-7

Orbital Development After Enucleation Without Orbital Implant inEarly Childhood

Purpose:

To evaluate the development of orbitalvolume in 5 adults who underwent enucleation with-

ABSTRACTS

681

out orbital implant during early childhood, using re-constructed computed tomography (CT) images.

Materials and Methods:

The orbital volume of 5adults who underwent enucleation without orbitalimplants during early childhood was measured usingCT images, and the results were compared betweenthe anophthalmic orbit and the unaffected orbit ineach case. The shape of maldevelopmental orbit andthe relationship between orbital development andreplacement of the prosthesis were also investigated.

Results:

Orbital development in patients who under-went enucleation without orbital implant duringearly childhood was delayed in comparison with theunaffected orbit, and the delayed development wasespecially remarkable at the part of orbit corre-sponding to the equator of the eyeball. Maldevelop-ment of the orbit was more severe in cases withoutreplacement of the prosthesis than with it.

Conclusion:

For the development of orbital volumein anophthalmos after enucleation, orbital volume inplace of the eyeball is required. Therefore, orbitalimplantation at the time of enucleation and replace-ment of the prosthesis with larger ones as the bodygrows more important. (J Jpn Ophthalmol Soc105:374–378, 2001)

Keiko Yago and Minoru Furuta

Department of Ophthalmology, Fukushima Medical University, School of Medicine

PII S0021-5155(01)00440-3

Three Ocular Sarcoidosis Patients Examined by IndocyanineGreen Angiography

Purpose:

To assess the findings of indocyanine greenangiography (IA) in patients with ocular sarcoidosis.

Subjects and Methods:

Three active ocular sarcoido-sis patients with various retinochoroidal findingswere diagnosed by biopsy or systemic examination.Two patients were diagnosed pathologically and 1patient was diagnosed clinically. IA and fluoresceinangiography (FA) were performed before and aftertreatment with systemic steroid administration.

Results:

IA revealed hyperfluorescence surroundingthe presumed granulomatous lesions. This hyperflu-orescence disappeared immediately after the treat-ment. FA showed hyperfluorescence continuingeven after therapy.

Conclusions:

It is proposed that the ring-form hyper-fluorescence in IA is due to accelerated vascular per-

meability in the active sarcoid granuloma. IA, whichvividly reflects activity of sarcoid lesions, is an im-portant tool for clinical evaluation of ocular sarcoi-dosis. (J Jpn Ophthalmol Soc 105:379–387, 2001)

Akiyasu Kanamori, Ryu Seya, Kazuko Saito,Atsushi Azumi and Akira Negi

Department of Ophthalmology, Kobe UniversitySchool of Medicine

PII S0021-5155(01)00441-5

Comparison Between the Anterior Chamber Configuration in the Supine Position and That in the Prone Position in Patients with Narrow Angle

Purpose:

To determine whether the anterior cham-ber configuration of patients with narrow angle ischanged in the prone position.Patients and Methods: The study included 16 eyes of16 patients whose anterior chamber angle was classi-fied as Shaffer 2 or narrower. The prone position test(PPT) and ultrasound biomicroscopy (UBM) wereperformed on every subject. In the UBM examina-tion, the following parameters were measured both inthe supine position and in the prone position: the an-gle-opening distance at 250 m from scleral spur(AOD 250), the angle-opening distance at 500 mfrom scleral spur (AOD 500), the trabecular-iris an-gle (TIA), and the anterior chamber depth at the cen-ter of the cornea (anterior chamber depth, ACD).Results: While the intraocular pressure was higher af-ter PPT than before the test, every subject was evalu-ated as negative for PPT. Mean value of every parame-ter examined was lower in the prone position than inthe supine position (AOD 250: 114 m vs. 128 m,AOD 500: 121 m vs. 144 m, TIA: 12.1 degrees vs.15.5 degrees, ACD: 1966 m vs. 2002 m), and thechange in ACD was statistically significant (p � 0.013).Conclusions: The anterior chamber configuration ofpatients with narrow angle is changed in prone posi-tion. Such a change can occur in patients classified asnegative for PPT. (J Jpn Ophthalmol Soc 105:388–393, 2001)

Rena Sano*, Toru Kurokawa*, Yasuo Kurimoto*, Daisuke Miyazawa† and Nagahisa Yoshimura*

*Department of Ophthalmology, Shinshu University School of Medicine; †Department of Ophthalmology, Kobe City General Hospital

PII S0021-5155(01)00442-7