Patented Technology for Enhanced Cannabis Delivery to the Skin

Ovation Science is disrupting the market with highly effective topical and

transdermal products all powered by its drug delivery system that is

protected by patents and backed by over 20 years of science.

MAY, 2019

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www.OvationScience.com

CORPORATE

PRESENTATION

T H I S P R E S E N TAT I O N B E L O N G S E X C L U S I V E LY T O O V AT I O N S C I E N C E I N C . I T D O E S N O T I M P LY A N O F F E R I N G O F S E C U R I T I E S .

F O R W A R D - L O O K I N G S TAT E M E N T S :

T H I S P R E S E N TAT I O N C O N TA I N S F O R W A R D - L O O K I N G S TAT E M E N T S W I T H I N T H E M E A N I N G O F S E C T I O N 2 7 A O F T H E S E C U R I T I E S A C T O F 1 9 3 3 A N D

S E C T I O N 2 1 E O F T H E S E C U R I T I E S E X C H A N G E A C T O F 1 9 3 4 . A C T U A L R E S U LT S C O U L D D I F F E R M AT E R I A L LY F R O M T H O S E P R O J E C T E D I N T H E F O R W A R D - L O O K I N G S TAT E M E N T S A S A R E S U LT O F T H E R I S K - R E L AT E D

F A C T O R S S E T F O R T H H E R E I N .

N O T F O R D I S S E M I N AT I O N I N T H E U S A

SAFE HARBOR

STATEMENT

NOTE: OVATION does not sell or distribute any products that are in violation of the

United States Controlled Substances Act (US.CSA). The company does sell its

Invisicare polymer to its licensees.

OVATION SCIENCE INC. – ABOUT US

We have the exclusive world-wide rights to all cannabis (hemp and marijuana) and hemp seed oil products

formulated with Invisicare®; a patented drug delivery technology;

Our business model is to develop, market and/or license out our topical and transdermal formulations powered by Invisicare® technology to cannabis companies globally.

We offer high-margin, topical and transdermal products for the medical, recreational and consumer /

beauty markets.

OVATION IS UNIQUE FROM OTHER INFUSED PRODUCT COMPANIES AS WE LEVERAGE OUR EXPERTISE IN THE PHARMACEUTICAL INDUSTRY TO DEVELOP HIGHLY EFFECTIVE, PATENT-PROTECTED PRODUCTS;

& WE HAVE THE RESULTS TO PROVE IT.

WE ARE ALL ABOUT THE SCIENCE!

NOTE: OVATION does not sell or distribute any products that are in violation of the United States Controlled

Substances Act (US.CSA). The company does sell its Invisicare polymer to its licensees

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Ovation Science Inc. (“OVATION”), is a topical research and development company with a patented drug delivery technology backed by over 20 years of R&D.

OVATION SCIENCE INC.

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Stock Symbol: OVATION trades on the Canadian Securities Exchange under the symbol CSE:OVAT. (November 2018)

Capitalization: •Issued & Outstanding: 23,153,121 •Reserved for Issuance: 6,754,433 •Fully Diluted: 29,905,454

Share Price: (May 7/19): $.64 Market Cap: $14.8 million CDN Business Model: (1) Ovation will generate online and wholesale revenue from the sale of its own product lines. (2) Ovation’s out-licensing business model generates revenue from multiple revenue streams including development fees, licensing fees, on-going royalties and sales of Invisicare polymer to its licensees.

THE MARKET

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The cannabis market is exploding. The 2018 Farm Act has had a significant impact on the forecasted CBD

and topical markets.

*Global Market Insights, Inc. “U.S. Medical Marijuana Market Research 2018-2024 Forecast Report”

** Jefferies Global Research & Strategy

MARKET PROJECTIONS*

US Medical MJ Market USD$ 8 billion by 2024

US Medical MJ Market for skin-related conditions 13.7% growth (CAGR)

US Medical MJ Market for pain-related conditions 13.3% growth (CAGR)

US Medical MJ Market for all topical applications USD$ 179.3 million in 2017 14.3% growth (CAGR)

Global Medical MJ Market USD$ 55 billion by 2024

Global Medical MJ Market for all topical applications USD $349.1 million in 2017

Globally CBD beauty products** US$25billion in next decade

OVATION SCIENCE INC.

KEY INVESTMENT HIGHLIGHTS - CSE:OVAT

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• Products formulated with Invisicare®: a high performance skin delivery technology which enhances the delivery of ingredients to and through the skin.

• Patented in 11 countries including Canada & USA, Australia, Europe and Asia.

PATENTED TECHNOLOGY With

20 YRS of R&D

• Lighthouse Strategies LLC: a private US-based company that holds multiple Nevada and California licenses & has aggressive US expansion plans.

• Four products launched including CBD and THC.

KEY US LICENSE ALREADY In PLACE

• Wholesale and online revenue from Ovation’s own product lines.

• Revenue generated from Licenses include: Product Development fees Licensing fees Royalties based on sales of product by licensees The sale of Invisicare® polymers to licensees

MULTIPLE PRONGED BUSINESS MODEL With LOW COGS

• Over 75 years of combined pharmaceutical product development expertise

• Ovation’s highly experienced Management team & Board of Directors has expertise in pharmaceutical development, public markets, finance & marketing.

EXPERIENCED MANAGEMENT

TEAM

KEY EXECUTIVES & BOARD OF DIRECTORS OVATION SCIENCE INC.

Terry Howlett, President, Director Co-Founder Has over 35 years of entrepreneurial, business management & public market initialization experience in the pharmaceutical and skincare markets.

Doreen McMorran, COO, Director Co-Founder Brings 25+ yrs of experience in the medical & pharmaceutical industry, specifically in the areas of strategic planning, sales & marketing of skincare / dermatology products.

Logan Anderson, CFO, Director For 30+ years has held director & senior executive officer positions in numerous public companies due to his considerable financial and management expertise.

Dave Ryan, Head of IR, Director Has extensive experience in investment and public markets. For the past 25 years he has been influential in bringing multiple Initial Public Offerings to market.

Ian Howard, Director Has 40+ years of extensive experience in: international dermatology marketing & education, advertising, sponsorship with private, Fortune 500 companies & government.

Joan Chypyha, Director Has over25 years of experience in the pharmaceutical industry in various senior management positions: President & GM (Canada) for TSX company & GM of NASDAQ companies & >20 licensing deals & product launches to her credit.

James Roszell, PhD, Head of Product Development, Dr Roszell is an doctoral chemist and developer of Invisicare®, with over 40 years experience in product formulation, experimental design, analysis, and method validation.

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OVATION has a team with decades of experience in business development, product research & development, and financial markets

MEDICAL DERMATOLOGY ADVISORY BOARD

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WHERE SCIENCE, MEDICINE & CANNABIS CONVERGE

Ovation has formed a Medical Dermatology Advisory Board for cannabis formulated products with prominent international dermatologists & chaired by Dr. Chuck Lynde (University of Toronto).

The objective of the Advisory Board is to help Ovation to reinforce the science behind its products by providing guidance, along with clinical, scientific, research and strategic advice to the Company as it continues to advance it’s topical and transdermal cannabis product development and to maintain and support the Company’s advantage in the topical cannabis market globally.

CHAIR: Dr. Charles Lynde, MD: Dr. Lynde chairs OVATION’s advisory board. Dr. Lynde is an associate professor in the department of medicine at the University of Toronto and holds a clinical teaching position at the University Health Network. He is also medical director of the Lynde Institute for Dermatology and Lynderm Research. He is a principal investigator and has conducted over 150 research studies in the management of dermatologic conditions. Dr Lynde has served in various roles for the Canadian Dermatology Association (CDA) and American Academy of Dermatology, including president of the CDA. He has also been the recipient of the CDA Award of Merit. Richard Thomas, MD, FRCPC: After receiving his medical degree in the UK, Dr. Thomas became an established clinical dermatologist in Vancouver, Canada, and Clinical Assistant Professor at the University of British Columbia & currently is a dermatologist at Sidra Hospital and Research Centre for Women and Children in Doha, Qatar. He has over two decades of experience in dermatology including dermatological clinical trials & is currently the Managing Editor of Skin Therapy Letter, a peer-reviewed journal, indexed with the National Library in Washington and distributed to over 29,000 dermatologists worldwide. Leon Kircik, MD, FAAD: Dr. Kircik is the Medical Director of DermResearch, PLLC and Physicians Skin Care, PLLC in Louisville, Kentucky, as well as Associate Clinical Professor of Dermatology at Indiana University Medical Center and Icahn School of Medicine at Mount Sinai Medical Center. He has been the principal investigator of clinical trials for dermatological conditions & has lectured extensively both nationally and internationally. He is on the editorial board of Journal of Drugs in Dermatology, Practical Dermatology, The Journal of Clinical & Aesthetic Dermatology, and Case Report in Clinical Pathology.

OUR TECHNOLOGY – THE UNIQUE STORY

Invisicare is a powerful yet flexible combination of polymers (like “tubes”) that incorporate key ingredients within its structure.

• Forms a protective bond that holds ingredients on your skin resisting both rub-off & wash-off while your skin still breathes naturally

Skin Binding:

• “Super Charges” ingredients & delivers targeted levels to your skin

Superior Delivery -Increased Release:

• Has a stabilizing effect on ingredients so they don’t break down & are available to do what they are intended to do

Stabilizes Ingredients:

• Improves your skin barrier function by retaining water / moisture in your skin & preventing damage from outside elements & toxins

Skin Friendly Skin Barrier:

• Formulations do not contain alcohol, parabens, waxes or other organic solvents

Less Additives:

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OUR PATENT PORTFOLIO

Comprehensive patent protection for all Ovation products:

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INVISICARE TECHNOLOGY PATENTS Covers three key areas: Composition, Manufacturing & Use

□ USA Divided into 4 patents / Latest US Expiry 2029);

□ INTERNATIONAL: Europe (France, Switzerland, UK, & Germany), Canada, Australia, China, India, Hong Kong & S. Korea (Expiry 2022).

INVISICARE US PATENT NUMBERS

8,481,058

8,318,818

7,674,471

6,756,059

PATENTS EXPIRY COMMENTS

ACNE 9,149,490 2030 Composition, & Methods for Manufacturing & Using

CATIONIC 8,735,422 2030 Composition, & Methods for Manufacturing & Using

SUNSCREEN 8,128,913 2029

Enhanced UVA Absorber Stability & Methods (Achieved 8+ hours of photo-stability of avobenzone)

DERMAL BARRIER 6,582,683 2020 Composition: Original patent submission

INVISICARE US PRODUCT PATENTS:

OUR SCIENCE

Skin Binding Study – in vivo (California Skin Research Institute (CSRI), CA)

• 30 Subjects Applied Invisicare product

• Forearms were scrubbed for 2 mins. with gauze saturated with 5% Ammonium Hydroxide at intervals of 10 minutes, 2 hours and 4 hours.

• Results: Our product was bound to skin >than 4 hours, even after 6 minutes of scrubbing.

Skin Moisture Study – in vivo (BioScience Laboratories, MT)

• 20 Subjects: ½ applied Invisicare product

• 30 Second Wash & Rinse 10x per Day for 5 days

• Results: 4 subjects without Invisicare dropped out due to dermatitis.

TEWL and Corneal Moisture Readings showed increased moisture with our formulation.

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» DRUG DEVELOPMENT PROTOCOLS: R&D IS CONDUCTED USING PRESCRIPTION DRUG PROTOCOLS & TECHNIQUES TO DEVELOP FULLY TESTED, STABLE PRODUCTS

1. HPLC Analysis – Determine Purity Of Ingredients; 2. RELEASE STUDIES – Determine the amount of CBD / THC that is released to the skin; 3. ACCELERATED STABILITY (40°C) - To Prove Shelf-life; 4. FRANZ CELL DIFFUSION ANALYSIS: - Determines the Penetration Rate & % Release of Ingredients Transdermally.

PRODUCT DEVELOPMENT R&D

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HOW OVATION PRODUCTS COMPARE

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Releases More Cannabis to & through the Skin

Delivered by Patented Technology

Resists Wash-Off & Rub-Off For Longer Lasting Relief

Let’s Your Skin Breathe; Won’t Clog Your Pores

Products Backed by 20 Years of Science

No Parabens, Waxes or Organic Solvents

High CBD & THC Options Available

Both Topical & Transdermal Products Available

THE PRODUCTS & THE RESULTS

DISRUPTIVE POSITIONING OVATION products are game changers in the infused cannabis marketplace,

replacing the “homemade” persona of current topical products with science-based, efficacious products that will benefit consumers around the globe. We “super charge” actives; putting more cannabis to work:

OVATION’s topical products released more CBD to the skin (40% vs 3% from a market leader that was tested) OVATION’s transdermal products show up to an 81% penetration over 6 hours (vs average penetration of other products reported at @10-25%) (Results of a Franz Cell Diffusion Analysis)

THE RESULTS

TOPICAL DELIVERY 3% vs 40% (Ovation) @ 2Hrs

TRANSDERMAL PENETRATION 10%-25% vs 81% (Ovation) @ 6 Hrs % Comparison

of Active CBD Delivery

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OVATION’s PRODUCT LINE

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ARLO BEAUTY:

OVATION’s anti-aging product line in the USA is called ARLO Beauty. This prestigious anti-aging product line includes an anti-aging day cream, night cream, eye cream, hand & body lotion and future launches of its hand cream, foot balm and broad-spectrum sunscreen.

Anti-Aging Day Cream Anti-aging - ceramide that “water proofs” the skin and helps reduce the look of fine lines and wrinkles

Anti-Aging Night Cream Anti-aging peptide with 4 repair functions to fight the signs of aging

Anti-Aging Eye Cream Anti-aging - decreases puffiness & under eye dark circles. Contains green tea & cucumber

Hand & Body Lotion Moisturizing body care: • Restore moisture levels • Get smooth, satiny skin • Repair elasticity • Nourish your skin • Prevent moisture loss

FUTURE LINE EXTENSIONS:

Broad- Spectrum Sunscreen HIGHEST FDA CLAIMS: broad spectrum (SPF30), water resistant 80 minutes, US patent for stabilizing sun filters for 8+hrs

Hand Cream A moisturizing cream that leaves hands feeling soft and smooth

Foot Balm Relaxing peppermint, thick moisturizing & protecting cream, CBD for inflammation

ARLO BEAUTY SUNSCREEN

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The FDA criteria indicate that UVA sunscreens must have a minimum critical wave-length of 370nm in order to be labeled “broad spectrum”. A waterproof or sweat proof claim can only be “water-resistant up to 40 or 80 minutes.” In April 2019 OVATION received the results of an independent testing of its ARLO Beauty sunscreen and it successfully passed the highest level of FDA requirements: (1) broad spectrum and (2) 80 minutes water-resistance.

Benefits of ARLO Beauty Sunscreen:

Broad spectrum protection from harmful UVA and UVB rays

80 minute water resistance - highest FDA designation obtainable

Glides on smoothly without any residue

Won’t run or perspire into your eyes

No alcohol / No parabens / No fragrances

Enhanced with CBD

Additional Patent Protection: In addition to the Invisicare patent protection, Ovation’s sunscreen has also been granted: "Sunscreen Composition With Enhanced UVA Absorber Stability and Methods", US Patent #8128913. Avobenzone, a sun filter, can lose up to 36% of its potential for UV absorption after only 1 hour of exposure to sunlight if not stabilized. Our patent is for stabilizing Avobenzone for 8+ hours.

US LICENSEE

A Nevada/California-based cannabis marketing company with multiple successful brands & other cannabis related enterprises for which they have generated record breaking online followings.

Rights include: exclusive for cannabis product in licensed US dispensaries & non-exclusive for outside of US dispensaries.

They have a state-of-the art cannabis facility in San Diego (cultivation, dispensary and production) which will also house ARC, a cannabis medical research center which is supported by Lighthouse.

Building momentum for their brands is Lighthouse’s expertise and strategy. They leverage their infrastructure for economies of scale. They have an aggressive expansion plan which will take OVATION formulated products across the USA both within and outside of licensed dispensaries under their brand management company Cannabiniers.

Four products developed by Ovation have been launched by Cannabiniers under the brand name BASKiN.

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BASKiN PRODUCTS:

#1 Selling Topical in Nevada Dispensaries (Source: HeadSet.io, April 2019): BASKiN + Extended Wellness Cream (400mg CBD/60ml -transdermal);

BASKiN Extended Wellness Cream (150mg CBD/60ml - topical);

BASKiN Sport (300mg CBD/90 ml - transdermal);

BASKiN GLOW (50mg CBD / 500 mg THC/ 60ml – transdermal ) “Recreational” Cream.

BASKiN TESTIMONIALS

This past weekend my wife and I were in Las Vegas and purchased the BASK cream. She has had various types of pain management and nothing worked as well as this cream. (Don- New York) I have had IBD associated arthritis for the past 6 years, and live with some degree of pain almost all the time. I have tried numerous prescription drugs to no avail. When I had a terrible flare up about three weeks ago, I tried your product. I have been using it now for two weeks and within a half hour have found that the pain has significantly subsided. I have been able to resume my daily routine. (Roshana- Brooklyn) I want to extend my thanks and congratulations for creating such a fine product. I have suffered osteoarthritis in my knees for almost thirty years. I have tried everything, short of knee replacements, that was offered by the pharmaceutical and natural products industry. The Bask+ cream gave me more relief overnight than I have ever had from any other product or treatment. It sounds strange, but I really look forward to each application. (Jim – Brooklyn)

TESTIMONIALS:

I purchased two of your “Extended Wellness Cream” 400mg of CBD while I was in Las Vegas. This has been the only product that has helped my wife, who has a cervical fusion from C2 down to T1. (Chad – San Diego)

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FUTURE GROWTH

• Currently the prescription pet market generates almost $14 billion in sales in the USA.

• OVATION will enter the animal health market with CBD/THC powered topical and transdermal products to help animals with pain / arthritis, inflammation, skin irritation / dry skin, and even insect bites.

• Pharmaceutical grade or synthetic cannabinoids (“laboratory-derived”); just like a prescription drug (products that require FDA/Health Canada approvals) are future product line extensions.

• OVATION is pursuing potential pharmaceutical companies that use cannabis for topical and transdermal prescription products.

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Short & long term revenue in progress from ARLO Beauty

& US licensee

Market has exponential growth

& global

prospects

Game changing, high-margin,

patented products in high demand

Experienced team of executives,

directors & advisors

INVESTMENT SUMMARY OVATION SCIENCE INC.

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THANK YOU

For more information contact:

Terry Howlett, President & CEO Email: terry@ovationscience.com Or Dave Ryan, Director, Investor Relations Email: dave@ovationscience.com For Business Development inquires contact: Doreen McMorran, COO, Director doreen@ovationscience.com

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