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Limbic system and higher brain function
Andreas Talgø Lie
LIMBIC SYSTEM
Limbic system - structures
Limbic system - function
• Emotions
• Long term memory
• Olfaction
• Behavior
• ANS
• Sexual behavior
Limbic system - summery
Structure Function
Hypothalamus Autonomic nervous system
Amygdala Agression center
Thalamus Relay station for sensations (except olfaction)
Hippocampus Convertion of short term memory to long term memory
Reward system Mesolimbic dopamine pathwayMesocortical dopamine pathway
* Satiation
Addiction
Addiction
Addiction
Punishment system
Higher brain function
Memory
• Memory: learning that has persisted over time – information that has been stored and in many cases can be recalled
Synaptic placidity mechanism of memory and learning
Long term potentiation - LTP
Memory
Sensory memory/ Working memory
Learning - habituation
Learning - sensitization
Learning – conditioned reflexes
USUR
CR
Neutral stimuli
CS
Trial
Amnesia
Retrograde Antrograde
Language disorders
• Dysarthria - Inability to produce words
• Dysphasia/Aphasia - Higher-order inability to speak
• Dysphonias/Hoarse voice - Inability to produce sounds
Language disordersDysphasia/Aphasia Lesion
Broca Non-fluent with intact comprehension
Wernicke Fluent with impaired comprehension and repetition
Conduction Poor repetition but fluent speech, comprehension intact
Anomia Consistent inability to produce words for things desired to talk about
Receptive aphasiaBA: 22
Expressive aphasiaBA: 44 and 45
Conduction aphasia
Association areas - prefrontal
o Planning for voluntary movement, the future
o Consideration of consequences of actions before following through
o Predictions
o Solving logical/math problems
o Self control in regards to social, moral, ethical laws and norms
Association areas – parieto-occipito-temporal area
• Analysis of spatial coordination
• Area for language comprehension
• Area for visual language (reading)
• Area for associating vision with memory
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