DNA REPLICATION

Jessica Leung

Block D

http://farm3.static.flickr.com/2272/2073342439_cfecc98a58.jpg

BASIC INFORMATIO

N ABOUT DNA

NUCLEIC ACIDS

Storage, Transmission, and use genetic information

Types: DNA and RNA

Made of Nucleotides

A pentose sugar, phosphate group, and a nitrogen-containing base

Phosphodiester linkages

http://upload.wikimedia.org/wikipedia/commons/2/2c/RNA_chemical_structure.GIF

DNA STRUCTURE: 4 KEY POINTS Double stranded helix Right handed Anti-Parallel Outer edges of the nitrogenous bases are

exposed in minor and major grooves

http://images.wellcome.ac.uk/indexplus/obf_images/6a/1b/dba050918296decdf63926d0b3af.jpg

http://farm4.static.flickr.com/3131/2849019437_d670cd8086.jpg

http://farm4.static.flickr.com/3041/2735339035_62c0c6216d_o.jpg

http://upload.wikimedia.org/wikipedia/commons/9/9d/Water_drop_on_a_leaf.jpg

Double stranded helix Right handedAnti-ParallelComplementary Base Pairings

5’

3’

3’

5’

Maj

or g

roov

e

Min

or g

roov

e

BASE PAIRINGS

DNA: Adenine, Cytosine, Guanine, Thymine

RNA: Adenine, Cytosine, Guanine, Uracil

DNA REPLICATION!

DNA REPLICATION IN TWO STEPS (THE IDEA)

Double Helix is unwound New Nucleotides are added

http://upload.wikimedia.org/wikipedia/commons/7/78/DNA.three-models.1.jpg

http://images.wellcome.ac.uk/indexplus/obf_images/1f/db/51ca61b971d466050f9ed7d38edb.jpg

THE BIG IDEA

http://www.multiplemomsrock.com/images/clamp.jpg http://www.tsl.state.tx.us/ld/projects/trc/2006/manual/illos/glue.jpg

http://upload.wikimedia.org/wikipedia/commons/5/51/Leading_strand_replication.png

Ligase

Sliding DNA

Clamp

BIBLIOGRAPHY

Sadava, David, H. Craig Heller, Gordon H. Orians, William K. Purves, and David M. Hillis. Life The Science of Biology. New York: W. H. Freeman, 2006. Print.