Heme iron tablet supplements have been in use in Scandinavia for
more than 30 years. There has been no cases of serious side-effects
or poisonings reported a>er use by literally millions.The raw
material is pharma-grade and comes with all necessary
Is it safe?
Its an organic product based on bovine hemoglobin.
Natural hemoglobin contains a relatively low content of iron,
how does this work in tablets?
TradiAonally an iron salt such as Ferrous Fumarate has been
added in the tablets at manufacture to raise the total content of
Today there is a technology available that will transfer iron
ions from added Ferrous Sulphate directly to the protein part of
hemoglobin, which means the total content will be absorbed by the
heme iron pathway.
The OptiFer tablets contain only 18 mgs of iron. Is this
This has to do with the basic dose regulated for food
supplements, but since hemoglobin iron is so well absorbed, the
efficacy means that the dose can compete with non-heme products
with 50 mg or more per dose. (see Iron supplementaAon in pregnancy:
is less enough, Eskeland et al Acta Obstet Gyn Scand 76 1997)
It is advantageous with a steady and slow absorpAon. Also, doses
over 50 mg per day will inhibit zinc absorpAon. Heme iron in itself
aids absorpAon of non-heme iron. OpAFer tablets contain both heme-
and non-heme iron.
Is there an upper limit to raw material availability?
In pracAce, the food industry is equipped to produce much more
raw material than needed for supplement tablets.
Is the raw material, being organic, very sensitive?
The dried raw material powder when used as a in tablets is
totally inert over Ame and not suscepAble to any disturbance. The
product withstands Ame and heat and since the tablets are packed in
airAght blister charts also moisture to a degree. Supplement/Food
legislaAon however implies a best-before date, usually two or three
years from date of manufacture.
What about religious concerns, such as halal or kosher?
The product contains material derived from bovine hemoglobin,
which can be a sensiAve issue. However, when used purely as a
medical supplement for a situaAon which can be fatal, it is
therefore of no religious concern. (religious authority imam
Mohammed Saieed Waezi)
Are there other forms of heme iron and why is natural bovine
The heme iron in OpAFer products comes exclusively from bovine
sources, unlike the other major form Heme Iron PolypepAde, which is
fabricated out of porcine raw material by denaturing natural
proteins or by using proteolyAc enzymes. It is listed to have as
common side-effects gastro-intesAnal problems such as upset
stomach, gas, diarrhea or consApaAon. Also, Heme iron polypepAde
may cause your urine or stools to turn a reddish-brown or dark
In clinical studies natural heme iron preparaAons such as OpAFer
are reported to have the side-effects levels of placebo products.A
total of 134 drugs (706 brand and generic names) are known to
interact with heme iron polypepAde. Natural heme iron has no known
interacAons or side-effects.
www.opAfer.internaAonal www.hemeiron.com www.meditec.se