Unique selling propositions for heme iron

Heme iron USPs Unique selling proposi3ons for heme

iron

Heme iron is safe and natural

There are only two kinds of iron that we can use; heme iron from meat, poultry or fish and non-heme iron from vegetables, dairy products or chemically bonded iron in supplements. Syntethic non-heme iron in the standard iron prepara3ons has a low degree of uptake and oEen produces unpleasant side-effects.

The natural bovine heme iron in Op3Fer® is absorbed five 3mes more efficiently than non-heme iron and has excellent tolerability. Today heme iron has seen safe use in the Swedish pharmacy for more than twenty-five years with literally millions of users. Bovine hemoglobin powder have no reported serious side-effects or poisonings at all reported during this 3me

Food supplements with efficacy on par with prescrip3on prepara3ons

Op3Fer® tablets can be dosed once daily at one 3me even with up to 3-4 tablets without side-effects. They are more effec3ve than any other iron prepara3on per elementary iron due to a superior absorp3on.

Most of the iron in syntethic tablets is not taken up due to due to simultaneously ingested other foodstuff or drink or the clinical condi3on. The natural uptake of heme iron is 20 - 40 % whereas non-heme iron is taken up at best at 3-4 %.

Well tolerated non-prescrip3on supplement

Op3Fer® tablets have less side-effects than any other iron prepara3on and can be dosed once daily even with up to 3-4 tablets without side-effects. Op3Fer® tablets have a high compliance due to excellent tolerability.

Op3Fer® tablets naturally have an ideal slow release mechanism in themselves since the protein complex dissolves slowly. This gives a much-wanted steady and slow release of iron for an op3mal intake and extremely low side effect risk.

This also has a direct effect on compliance.




Safe and secure

It is unlikely that poisonings can happen with heme iron even for liUle children. The so-called Mucosa barrier that fails in sudden high-doses of ferric iron is not cri3cal when using heme iron. The hemoglobin will not dissociate in gastric acid meaning that no free toxic iron ions will appear.

Heme iron in low doses is basically side-effects free. In all studies the side-effects level is around 10 %, which is iden3cal to placebo.

Oral non-heme iron products are known to have a side-effects ra3o of up to 30 %.




Easy dosage

Op3Fer® tablets have a normal dosage of one tablet per day and it is quite possible to increase the dose up to three tablets per day without side effects. The tablet may be taken at any 3me during the day.

For chronics it's been shown that heme iron therapy is ideal sionce the efficacy or tolerance do not change over 3me. This is not the case for regular non-heme iron supplements.

Many chronics given intravenous iron are bound to visi3ng a clinic regularly. Heme iron tablet therapy is simple and gives for instance the freedom to travel.

Absorp3on steady and higher than for non-heme iron

The Op3Fer tablets erode over several hours, giving a slow and steady infusion of iron.

Absorp3on regardless of simultaneously ingested other medica3on, food or drink. Heme iron will be absorbed regardless of clinical condi3on

A steady absorp3on is also important for constant uptake, since there is an upper limit when uptake is no longer efficient.

Large prospec3ve buyer groups: Fer3le females and pregnants

The biggest group for iron supplementa3on is found among all fer3le females who lose blood through menses and need replacement. It is es3mated that one in every four fer3le women need con3nuing supplementa3on. This is the same in all countries globally

Secondary large target buyer groups are pregnants and those planning pregnancy, the elderly and sports.

Large prospec3ve buyer groups: Chronics

A large group of users is all who suffer from chronic diseases that are related to anaemia. E.g Chronic Kidney Disease - CKD, Inflammatory Bowel Disease - IBD, among others. The most common therapy is intravenously given iron.

Researchers have found that intravenous iron injec3ons cause periods of exacerba3on of oxida3ve stress in the circula3on. Addi3onally the iron content in the body is oEen too high, which is associated with chronic inflamma3on and vascular damage.

Easier to use and less hard on the system is heme iron therapy.

Large prospec3ve buyer groups: Health professionals.

Target groups for marke3ng include General prac33oners, Gynaecologists, Midwives, Nurses and personnel within jobplace healthcare (including school health). They are the ones that diagnose anemia or low blood counts. Their recommenda3ons for treatment is central.

Heme iron is also ideal for large popula3on therapy in that it is reasonably priced and will not give poten3ally therapy-ruining gastro-intes3nal side-effects.

Lowest price per day

One tablet per day is enough bio-available iron for con3nual usage. Price per day is lower than compe3tors on the market, capsules and significantly lower than for tonics.

Heme iron tablet therapy is reasonably priced and the efficay is enough especially over longer 3me.

Price is a frac3on of the price of intravenously given iron, not to men3on transfusions.

The Op3Fer® Series of Heme-Iron supplements easily correct moderate to low iron values.

Op3Fer® products are very effec3ve and will not give unpleasant side effects

Health & Medicine

Unique selling propositions for heme iron