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TIME IS OF THE ESSENCE PAIN IS NOT AN OPTION
Anutra-Anesthetic Delivery and Buffering System
• Precisely delivers up to 6Ml (3 Regular Dental Carpules) in a single syringe.
• Allows For buffered or non-buffered Lidocaine
• Disposable Cartridge is good for 4 Days
• Fully disposable Syringe
Anutra by Infusion Medical
Anutra-Anesthetic Delivery and Buffering System
• Precisely delivers up to 6Ml (3 Regular Dental Carpules) in a single syringe.
• Allows For buffered or non-buffered Lidocaine
• Disposable Cartridge is good for 4 Days
• Fully disposable Syringe
Anutra by Infusion Medical
The Problems Buffering Solve
1. Saves Time: Buffered anesthetic decreases time of onset from 12-15 minutes to less than 2 minutes on average
2. Reduces Pain: Buffering (adding Sodium Bicarbonate) Lidocaine reduces the acidity and thus the pain and sting from a shot
3. Increases Revenues: With faster and more predictable onset of anesthesia, more patients can be scheduled in a day
4. Improves Efficiency: Reduces steps required for anesthesia and enables multiple shots from one syringe not currently possible
The Problems Buffering Solve
1. Saves Time: Buffered anesthetic decreases time of onset from 12-15 minutes to less than 2 minutes on average
2. Reduces Pain: Buffering (adding Sodium Bicarbonate) Lidocaine reduces the acidity and thus the pain and sting from a shot
3. Increases Revenues: With faster and more predictable onset of anesthesia, more patients can be scheduled in a day
4. Improves Efficiency: Reduces steps required for anesthesia and enables multiple shots from one syringe not currently possible
Saves Time: Percentage of patients fully numb vs. minutes since given anesthetic
Stanley F. Malamed
Reduces pain significantly
6%
44%
0%
10%
20%
30%
40%
50%
Controlled Anesthetic Buffered AnestheticStanley F. Malamed
Patients that reported zero Pain
1/18 8/18
Patients Prefer Buffered Anesthetic
11%
17%
72%
0%
20%
40%
60%
80%
Preferred Non-Buffered Anesthetic
No Preference Preferred BufferedAnesthetic
Stanley F. Malamed
2/18
3/18
13/18
Increases revenues
Makes buffering a no brainer:
$300 - $1,200 increase in potential daily revenue for a cost of $50
X
=
Time saved per patient (mins)
10 min
# patients per day 6
Time saved per day (hr)
1 hour
Extra procedures per day (in $)
$ 300 – $1200
Why buffering has been the elusive holy grail
Storage & shelflife • Buffered Lidocaine cannot be stored reliably
• Shelf life is reduced significantly by buffering
Effectiveness • Buffered anesthetic effectiveness decreases after 2 minutes
Cost & complexity • Mixing precise ratio in real time is complicated and time consuming
• All solutions to date have been extremely expensive
Anutra-Anesthetic Delivery and Buffering System
Anutra Dispenser Highlights
• Portable, one-handed, small footprint, purely mechanical
• Reusable, easily cleanable
• Dispenser accurately delivers 0.1ml of Drug A (sodium bicarbonate) by twisting knob one click
Accomplished by precise lead screw and slider mechanisms
• Connected syringe accurately doses 1 ml of Drug B (lidocaine) by pulling plunger one click
• Counter aids clinician in pulling multiple doses into one syringe
Anutra Dispenser Highlights
• Portable, one-handed, small footprint, purely mechanical
• Reusable, easily cleanable
• Dispenser accurately delivers 0.1ml of Drug A (sodium bicarbonate) by twisting knob one click
Accomplished by precise lead screw and slider mechanisms
• Connected syringe accurately doses 1 ml of Drug B (lidocaine) by pulling plunger one click
• Counter aids clinician in pulling multiple doses into one syringe
Anutra Dispenser Design
What you will get
Anutra Disposable Cassette
•50ml 2% Lidocaine•1/100,000 epi
•BicarbonateDisposable Syringes
Anutra Syringe Design
Anutra Syringe Highlights
• Audible & Haptic Feedback
• Double Sided volume Labeling
• Multiple doses (6 Ml), one syringe
• Ergonomic
• One-handed aspiration
• Optimized diameter & length
Anutra Syringe Highlights
• Audible & Haptic Feedback
• Double Sided volume Labeling
• Multiple doses (6 Ml), one syringe
• Ergonomic
• One-handed aspiration
• Optimized diameter & length
Dental Vibe
• $495
• $1.19 / patient not including Anesthetic
• Uses the Distraction technique
• Still uses the archaic dental syringe
• Bulky
• No increase in efficiency
Dental Vibe
• $495
• $1.19 / patient not including Anesthetic
• Uses the Distraction technique
• Still uses the archaic dental syringe
• Bulky
• No increase in efficiency
The Wand STA
• Expensive Sells for $2000
• Slows down the Process
• Bulky and low portability
• $2.75 additional cost per shot ($3.50/ shot)
The Wand STA
• Expensive Sells for $2000
• Slows down the Process
• Bulky and low portability
• $2.75 additional cost per shot ($3.50/ shot)
St. Renatus-Nasal Spray
• Costs $20 per shot
• Predicting available market of $2.5 billion just in U.S. dental
• Still in FDA process
• Only works on upper maxillaries (excluding 2nd and 3rd
molars)
• 16% needed traditional bail out shot
• Will likely be niche product
St. Renatus-Nasal Spray
• Costs $20 per shot
• Predicting available market of $2.5 billion just in U.S. dental
• Still in FDA process
• Only works on upper maxillaries (excluding 2nd and 3rd
molars)
• 16% needed traditional bail out shot
• Will likely be niche product
VibraJect
• $275
• Uses the Distraction technique
• Still uses the archaic dental syringe
• Bulky
• No increase in efficiency
VibraJect
• $275
• Uses the Distraction technique
• Still uses the archaic dental syringe
• Bulky
• No increase in efficiency
Competitive Alternative: OnPharma
• Expensive $400 unit cost
• $300 / week retail = $ 9/shot with Lidocaine
• Cumbersome for multiple injections
• Yet over 1,000 already out there because of economics
Competitive Alternative: OnPharma
• Expensive $400 unit cost
• $300 / week retail = $ 9/shot with Lidocaine
• Cumbersome for multiple injections
• Yet over 1,000 already out there because of economics
Infusion Medical is the only solution that simultaneously reduces time and pain at an economically viable cost
• OnPharma
• The Wand
• Dental Vibe
• VibraJect
• St. Renatus
Onset Time Pain Initial Cost Cost per Shot
Anutra 2 min. Buffered $250 $5.00
OnPharma 2 min Buffered $450 $9.00
The Wand 12- 30 min. Slowed Injection $2000 $3.50
Dental Vibe 12- 30 min. Faked $495 $2.00
VibraJect 12- 30 min. Faked $275 $.75
St. Renatus 15-20 min. Nasal NA $20.00
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