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AMYOTROPHIC LATERAL
SCLEROSISLou Gehrig’s
Disease
Introduction
- Jean-Martin Charcot discovered 1869-Men most affected
-Still remains mostly a mystery
Diagnosis- Difficult to diagnose due to similarity to other curable neuromuscular disorders- Neurological exam to look for muscle weakness
- Use EMG/NCV studies and MRI to rule out other diseases
Transmission- 90% to 95% random due to no risk factors
- 5% to 10% of cases are inherited/ 20% of hereditary cases due to genetic defect that causes mutation of the enzyme superoxide dismutase 1
- Not all cases due to same thing so undiscovered genetic problems must exist
Signs and Symptoms
Symptoms-Twitching-Cramping-Stiffness of muscles-Trouble with muscle coordination -Speech problems-Stay aware and intellectual-Problems swallowing-Progressively symptoms get worse and more severe
Treatment-No cure has been found-Drugs like riluzole are used to improve lives of victims-Physical therapy, physicians, and constant aid help person feel more comfortable -All just prolongs death
Pictures
Source Listhttp://www.neurologychannel.com/als/diagnosis.shtmlhttp://als-lou-gehrigs-disease.suite101.com/article.cfm/alsamyotrophic_lateral_sclerosis
http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_amyotrophiclateralsclerosis.htm