Upload
lynhi
View
225
Download
0
Embed Size (px)
Citation preview
Interventions for preventing NIHLa Cochrane Systematic Review
Jos Verbeek, Erik Kateman, Thais Morata, Wouter Dreschler, Christina Mischke
© Finnish Institute of Occupational Health – www.ttl.fi
Can / do we prevent NIHL?
• Technically Yes:
• immediate effects of saw blades measured by IFA, Germany
• With noise-reduced saw blades, high sound level reductions can be achieved:
• Up to approx. 6 dB(A) with the saw idling• Up to approx. 6 dB(A) when sawing aluminium• Up to approx. 7 dB(A) when sawing wood panels• Up to approx. 11 dB(A) when sawing plastic profiles• Up to approx. 12 dB(A) when sawing hardwood
edge-banding
25.2.2013 1Esittäjän nimi 1
© Finnish Institute of Occupational Health – www.ttl.fi
Can / do we prevent NIHL?
• Implementation of technical measures ???
25.2.2013 2Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Cochrane Review
• Objective:
• To assess the effectiveness of non-pharmaceutical interventions for preventing occupational noise exposure and occupational hearing loss compared to no or alternative interventions
• Set out in 2006, first published in 2009, updated in 2012
25.2.2013 3Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Cochrane Colaboration
• International network dedicated to reviewing the effects of health care interventions.
• Well elaborated methods for systematic reviews published in electronic journal named Cochrane Library
• Named after Archie Cochrane, British epidemiologist
• OSH review group specialised in OSH interventions since 2004
22.2.2013 4Jos Verbeek
© Finnish Institute of Occupational Health – www.ttl.fi
What to prevent?
• Noise Exposure• Immediate noise attenuation
• TTS, MIRE, REAT• long-term (years)
• dB(A)
• Occupational NIHL:• Less loss / decrease over time
• All NIHL measures considered equivalent• Change at 4 kHz (last minus first measurement)• Standard Threshold Shift (STS)
• any definition / frequency / ear(s)
25.2.2013 5Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
What kind of interventions?
• Engineering and administrative controls
• Technical noise reduction measures
• Hearing Protection Devices
• Hearing Loss Prevention Programmes (HLPP)
25.2.2013 6Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
What kind of evidence?
• Evaluation studies that control for changes over time
• Randomised Controlled Trials
• Controlled Before After Study
• incl control group without exposure
• Interrupted Time Series
25.2.2013 7Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Results of review
• 25 included studies
• Design:3 RCTs, 1 quasi-RCT, 19 CBAs, 2 ITSs
• Interventions:2 Noise-reduction, 8 hearing protection, 15 HLPP
• Outcomes:• long-term
2 dB(A), 8 STS, 9 mean hearing loss, • short-term
2 TTS, 2 REAT, 2 MIRE
25.2.2013 8Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Risk of bias / quality
25.2.2013 9Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Results noise reduction
• Noise reduction measures• 1 study (Joy 2007) effect of regulation
• Uncontrolled case studies• Noise measurements very unreliable or quality
unreported.
25.2.2013 10Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Results Hearing Protection
• Hearing Protection immediate effects
• all HP reduced noise levels
• additional effect of noise cancellation
• For ear plugs instruction crucial • (Park 1991)
25.2.2013 11Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi
Results HLPP long term
• HLPP versus minor alternative (audiometry)(4)
• Berg 2009: no effect after 3 /16 year follow-up on STS
• Rabinowitz 2011: ± effect of noise exp monitoring on HL
• Seixas 2011: no effect of noise exp monitoring on noise
• Seixas 2011: no effect of info on noise levels
• HLPP well implemented versus less well (5)
• RR = 0.4 (95% CI 0.23 to 0.69) for STS • (Adera 1993/2000, Brink 2002, Simpson 1994)
• similar in Heyer 2011
22.2.2013 12Jos Verbeek
© Finnish Institute of Occupational Health – www.ttl.fi
Results HLPP vs No Exposure> 5 year follow-up
25.2.2013 13Esittäjän nimi
Study or SubgroupPell 1973Gosztonyi 1975Hager 1982Lee-Feldstein 1993
Total (95% CI)Heterogeneity: Tau² = 0.00; Chi² = 2.53, df = 3 (P = 0.47); I² = 0%Test for overall effect: Z = 0.97 (P = 0.33)
Std. Mean Difference0.020.15-0.1
0.2913
SE0.058673
0.16840.31630.1858
Total3997127
111
608
Total1173
7116
363
1623
Weight79.6%9.7%2.7%7.9%
100.0%
IV, Random, 95% CI0.02 [-0.09, 0.13]0.15 [-0.18, 0.48]
-0.10 [-0.72, 0.52]0.29 [-0.07, 0.66]
0.05 [-0.05, 0.15]
Year1973197519821993
HLP Program Non-exposed Std. Mean Difference Std. Mean DifferenceIV, Random, 95% CI
-0.5 -0.25 0 0.25 0.5Favours HLPP Favours Non-exposed
Study or SubgroupPell 1973Gosztonyi 1975Hager 1982Lee-Feldstein 1993
Total (95% CI)Heterogeneity: Tau² = 0.00; Chi² = 1.17, df = 2 (P = 0.56); I² = 0%Test for overall effect: Z = 1.48 (P = 0.14)
Std. Mean Difference0.020.15-0.1
0.2913
SE0.058673
0.16840.31630.1858
Total3997127
111
209
Total1173
7116
363
450
Weight0.0%
47.5%13.5%39.0%
100.0%
IV, Random, 95% CI0.02 [-0.09, 0.13]0.15 [-0.18, 0.48]
-0.10 [-0.72, 0.52]0.29 [-0.07, 0.66]
0.17 [-0.06, 0.40]
Year1973197519821993
HLP Program Non-exposed Std. Mean Difference Std. Mean DifferenceIV, Random, 95% CI
-0.5 -0.25 0 0.25 0.5Favours HLPP Favours Non-exposed
Plus Muhr 2006 and Davies 2008
© Finnish Institute of Occupational Health – www.ttl.fi
Conclusions
• Low quality evidence
• use of HP devices probably prevents NIHL
• unclear which components of HLPP effective
• compared to non-exposed, HLPP do not prevent NIHL well enough (still > 85 dB(A) rísk of NIHL)
• Practice• better implementation needed (noise reduction)
• Research• RCTs possible; need to test specific HLPP components
25.2.2013 14Esittäjän nimi
© Finnish Institute of Occupational Health – www.ttl.fi 25.2.2013 15Esittäjän nimi
Thank You!
15