Insulin s.c. depot: Heaps

Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208

Com

plex

ity

Size

Small molecule Drug Medium sized Molecule IgG Antibody 300-600 Da 1K – 3K Da 25,000 Da

Size and complexity : from small molecule to Protein

Self assembly Re-build take to the garage Ask for new robotics ! (3 computers,67 sensors) Built in instability

The Clyde Arc: “The Squinty Bridge”