Homo Sapiens Kallikrein

8/15/2019 Homo Sapiens Kallikrein

http://slidepdf.com/reader/full/homo-sapiens-kallikrein 1/8

Homo sapiens kallikrein-related peptidase 7 (KLK7), transcript variant 2, mRNA

NCBI Reerence !e"#ence$ N%&'277*2

1 ggagagggtg atgctggctc caagcctgac tctgctctcg agagctccag caggagaggc 61 ccttcctcgc ctggcagccc ctgagcggct cagcagggca ccatggcaag atcccttctc

121 ctgcccctgc agatcttact gctatcctta gccttggaaa ctgcaggaga agaagcccag 181 ggtgacaaga ttattgatgg cgccccatgt gcaagaggct cccacccatg gcaggtggcc

241 ctgctcagtg gcaatcagct ccactgcgga ggcgtcctgg tcaatgagcg ctgggtgctc 301 actgccgccc actgcaagat gaatgagtac accgtgcacc tgggcagtga tacgctgggc

361 gacaggagag ctcagaggat caaggcctcg aagtcattcc gccaccccgg ctactccaca 421 cagacccatg ttaatgacct catgctcgtg aagctcaata gccaggccag gctgtcatcc

481 atggtgaaga aagtcaggct gccctcccgc tgcgaacccc ctggaaccac ctgtactgtc

541 tccggctggg gcactaccac gagcccagat gtgacctttc cctctgacct catgtgcgtg

601 gatgtcaagc tcatctcccc ccaggactgc acgaaggttt acaaggactt actggaaaat 661 tccatgctgt gcgctggcat ccccgactcc aagaaaaacg cctgcaatgg tgactcaggg

721 ggaccgttgg tgtgcagagg taccctgcaa ggtctggtgt cctggggaac tttcccttgc 781 ggccaaccca atgacccagg agtctacact caagtgtgca agttcaccaa gtggataaat

841 gacaccatga aaaagcatcg ctaacgccac actgagttaa ttaactgtgt gcttccaaca 901 gaaaatgcac aggagtgagg acgccgatga cctatgaagt caaatttgac tttacctttc

961 ctcaaagata tatttaaacc aacctcatgc cctgttgata aaccaatcaa attggtaaag

1021 acctaaaacc aaaacaaata aagaaacaca aaaccctcag tgctggagaa gagtcagtga

1081 gaccagcact ctcaaacact ggaactggac gttcgtacag tctttacgga agacacttgg 1141 tcaacgtaca ccgagaccct tattcaccac ctttgaccca gtaactctaa tcttaggaag

1201 aacctactga aacaaaaaaa atccaaaatg tagaacaaga cttgaattta ccatgatatt 1261 atttatcaca gaaatgaagt gaaaccatca aacatgttcc aaaagtacca gatggcttaa

1321 ataatagtct ggcttggcac aacgatgttt tttttctttg agacagagtc tctgttgctt

1381 gggctgcaat gcagtgatgc aatcttggct cactgcaacc tccgcctcct gggttcaagt

1441 gattctcgtg cttcagcctc ccaagtacct gggactacag gtgtgcacca ccacaccagg 1501 ctaatttttt gtgtattttt actagagaca gggtttcacc atgttggcca gcatggtctt

1561 gaacgcctga cctcagatga tccacccacc ttggcctccc aaagtgctgg gattacaggc

1621 atgagccacc acggccagcc cacaatgata ttacaaacct attaaaaatg atacttagac 1681 agaattgtca gtattattca agaacattta ggctatagga tgttaaatga caaaaggaag 1741 gacaaaaata tatatgtatg tgaccctacc cataaaaaat gaaatattca cagaatcaga

1801 tctgaaaaca catgtcccag actgcatact ggggtcgtca tgaggtgtct ccttccttct

1861 gtgtactttt ccttgaatgt gcacttttat aacatgaaaa ataaaggtgg ggaaaaaagt

1921 caaaaaaaaa aaaa

Exon

1 ggagagggtg atgctggctc caagcctgac tctgctctcg agagctccag caggagaggc

61 ccttcctcgc ctggcagccc ctgagcggct cagcagggca ccatggcaag atcccttctc 121 ctgcccctgc agatcttact gctatcctta gccttggaaa ctgcaggaga agaagcccag

181 ggtgacaaga ttattgatgg cgccccatgt gcaagaggct cccacccatg gcaggtggcc

241 ctgctcagtg gcaatcagct ccactgcgga ggcgtcctgg tcaatgagcg ctgggtgctc

301 actgccgccc actgcaagat gaatgagtac accgtgcacc tgggcagtga tacgctgggc 361 gacaggagag ctcagaggat caaggcctcg aagtcattcc gccaccccgg ctactccaca

421 cagacccatg ttaatgacct catgctcgtg aagctcaata gccaggccag gctgtcatcc 481 atggtgaaga aagtcaggct gccctcccgc tgcgaacccc ctggaaccac ctgtactgtc

541 tccggctggg gcactaccac gagcccagat gtgacctttc cctctgacct catgtgcgtg 601 gatgtcaagc tcatctcccc ccaggactgc acgaaggttt acaaggactt actggaaaat

661 tccatgctgt gcgctggcat ccccgactcc aagaaaaacg cctgcaatgg tgactcaggg

721 ggaccgttgg tgtgcagagg taccctgcaa ggtctggtgt cctggggaac tttcccttgc



781 ggccaaccca atgacccagg agtctacact caagtgtgca agttcaccaa gtggataaat

841 gacaccatga aaaagcatcg ctaacgccac actgagttaa ttaactgtgt gcttccaaca

901 gaaaatgcac aggagtgagg acgccgatga cctatgaagt caaatttgac tttacctttc 961 ctcaaagata tatttaaacc aacctcatgc cctgttgata aaccaatcaa attggtaaag

1021 acctaaaacc aaaacaaata aagaaacaca aaaccctcag tgctggagaa gagtcagtga 1081 gaccagcact ctcaaacact ggaactggac gttcgtacag tctttacgga agacacttgg

1141 tcaacgtaca ccgagaccct tattcaccac ctttgaccca gtaactctaa tcttaggaag 1201 aacctactga aacaaaaaaa atccaaaatg tagaacaaga cttgaattta ccatgatatt

1261 atttatcaca gaaatgaagt gaaaccatca aacatgttcc aaaagtacca gatggcttaa


1381 gggctgcaat gcagtgatgc aatcttggct cactgcaacc tccgcctcct gggttcaagt 1441 gattctcgtg cttcagcctc ccaagtacct gggactacag gtgtgcacca ccacaccagg

1501 ctaatttttt gtgtattttt actagagaca gggtttcacc atgttggcca gcatggtctt 1561 gaacgcctga cctcagatga tccacccacc ttggcctccc aaagtgctgg gattacaggc

1621 atgagccacc acggccagcc cacaatgata ttacaaacct attaaaaatg atacttagac

1681 agaattgtca gtattattca agaacattta ggctatagga tgttaaatga caaaaggaag

1741 gacaaaaata tatatgtatg tgaccctacc cataaaaaat gaaatattca cagaatcaga 1801 tctgaaaaca catgtcccag actgcatact ggggtcgtca tgaggtgtct ccttccttct

1861 gtgtactttt ccttgaatgt gcacttttat aacatgaaaa ataaaggtgg ggaaaaaagt 1921 caaaaaaaaa aaaa

Exon 1

Exon 2

Exon 3

Exon 4

Exon 5

Exon 6

Gene1 ggagagggtg atgctggctc caagcctgac tctgctctcg agagctccag caggagaggc

61 ccttcctcgc ctggcagccc ctgagcggct cagcagggca ccatggcaag atcccttctc

121 ctgcccctgc agatcttact gctatcctta gccttggaaa ctgcaggaga agaagcccag

181 ggtgacaaga ttattgatgg cgccccatgt gcaagaggct cccacccatg gcaggtggcc

241 ctgctcagtg gcaatcagct ccactgcgga ggcgtcctgg tcaatgagcg ctgggtgctc 301 actgccgccc actgcaagat gaatgagtac accgtgcacc tgggcagtga tacgctgggc

361 gacaggagag ctcagaggat caaggcctcg aagtcattcc gccaccccgg ctactccaca 421 cagacccatg ttaatgacct catgctcgtg aagctcaata gccaggccag gctgtcatcc

481 atggtgaaga aagtcaggct gccctcccgc tgcgaacccc ctggaaccac ctgtactgtc

541 tccggctggg gcactaccac gagcccagat gtgacctttc cctctgacct catgtgcgtg

601 gatgtcaagc tcatctcccc ccaggactgc acgaaggttt acaaggactt actggaaaat 661 tccatgctgt gcgctggcat ccccgactcc aagaaaaacg cctgcaatgg tgactcaggg

721 ggaccgttgg tgtgcagagg taccctgcaa ggtctggtgt cctggggaac tttcccttgc

781 ggccaaccca atgacccagg agtctacact caagtgtgca agttcaccaa gtggataaat 841 gacaccatga aaaagcatcg ctaacgccac actgagttaa ttaactgtgt gcttccaaca 901 gaaaatgcac aggagtgagg acgccgatga cctatgaagt caaatttgac tttacctttc

961 ctcaaagata tatttaaacc aacctcatgc cctgttgata aaccaatcaa attggtaaag

1021 acctaaaacc aaaacaaata aagaaacaca aaaccctcag tgctggagaa gagtcagtga

1081 gaccagcact ctcaaacact ggaactggac gttcgtacag tctttacgga agacacttgg 1141 tcaacgtaca ccgagaccct tattcaccac ctttgaccca gtaactctaa tcttaggaag

1201 aacctactga aacaaaaaaa atccaaaatg tagaacaaga cttgaattta ccatgatatt 1261 atttatcaca gaaatgaagt gaaaccatca aacatgttcc aaaagtacca gatggcttaa




1381 gggctgcaat gcagtgatgc aatcttggct cactgcaacc tccgcctcct gggttcaagt

1441 gattctcgtg cttcagcctc ccaagtacct gggactacag gtgtgcacca ccacaccagg

1501 ctaatttttt gtgtattttt actagagaca gggtttcacc atgttggcca gcatggtctt 1561 gaacgcctga cctcagatga tccacccacc ttggcctccc aaagtgctgg gattacaggc

1621 atgagccacc acggccagcc cacaatgata ttacaaacct attaaaaatg atacttagac 1681 agaattgtca gtattattca agaacattta ggctatagga tgttaaatga caaaaggaag

1741 gacaaaaata tatatgtatg tgaccctacc cataaaaaat gaaatattca cagaatcaga 1801 tctgaaaaca catgtcccag actgcatact ggggtcgtca tgaggtgtct ccttccttct

1861 gtgtactttt ccttgaatgt gcacttttat aacatgaaaa ataaaggtgg ggaaaaaagt

1921 caaaaaaaaa aaaa

Grapich

Fasta

>gi|333609284|ref|NM_139277.2| Homo sapiens a!!irein"re!ate# pepti#ase 7$%&%7'( transcript )ariant 2( m*N+

,,+,+,,,-,+-,-,,-++,-,+--,--,+,+,-+,+,,+,+,,---,

-,,+,-,+,,,-+,+,,,++-,,++,+-----,-,+,+---+-

,-+---+,--,,+++-,+,,+,++,++,+,,,-,+++,+--+--,+-,,,+-,-,++,+,,-++-,,+,,-,,-,-+,-,,++-+,-+-,,,+,,,--,,

-++-,+,,-,,,-,-+-,,+-,++,+-,++-,+,-++,-,+-,,,+,-,+-+,-,,,,++,,+,+,-+,+,,+-++,,-,++,-+--,+,,-+-++

+,++-,--++-,+-+-,-,-,++,-++-+,+,,+,,-,-+-+-,,-,++,+++,-+,,-,-,-,,++-,,+++-,-+-,--,,-,,,,+-++

,+,+,+-,-,+-----,+-+-,-,,-,,+-,-++,-+--+,,+-,

+,++,,---+++,,+--+-,,++++--+-,-,-,,-,,+-,+-++,+++++,

-,++-,,-,+-+,,,,,+,--,,-,-,+,+,,-+-,++,,--,,-,--,,,,++-----,,,++++-,++,,+,--++-++,-,-,++,--+++,-,,+-+++-

,+++-,+++++,+-,-++,++-,+,--++--++-,-,-,--+++,++++-,++,,+,-,+,,+,,+-,+-+-,++,-+++---,+---+----+++,+-+-+---+++



++-+-,-,--,+-+++++-+++--,,-+++,+-+++++++++++-+++,+++++

+++-+,-,-,,+,++,+,-+,-,+,++,+--++++-,,++-,,+,--,-++,

----+,,++,++--,,-++,-++,+,+--+--++---,++,-++--++---+,,++,++-+-,+++++++++++-++++-,-+,++++,+--,++---++-,+-+--

+---+-++,+++-,++,-,++++-++++-,--++++,-++,+-,,--+++-++-+,--,,--,,+++,+-,-----------,+,++,+,---,--,--,,,-,++-,+,-,+-,

++---,,-+-,++-,--,,,--++,-,+---,-,--+,-++,-+-,,,+-++,,-,-,+++++,,-++------,-,-+-----+-+,+,++,,,---+

+-,--,,+,+-,,---,++,-,+-+,+-,+-++--,,-+++,-,-,,

,+--++,,+-,+,++,,+,+++-,+-+--++++-+--+++++-,+-+--+,+

+,++--,-+,-+--+--++,+++---+,,-+-+,,+-,--+++-,+++++,,++,,++++++-+-+-+-,-+-,-,+-++-++++++-,+++-+--++,++-+,+--,++++++-,-+,

+-,+-+-,,,,-,-+-,+,,-,-------,-,-+------,++-,-,+----+-+++-,+++++-+++,,-,,,,++++++,-+++++++++++++

Genscan



Hasil Translate Fasta

+ rame '///////////////////////*M&+&-&&*++,+&*&++*&*+*"%&%%*-*&&M+H+-H,*+-++M+

,&-+*"M--+*+-,&*,**H+-+-H*M&M-"+*,

H"*%,++N&&+,+&*+M"&-+M*-+**-*-%+&+-*%-+M-,*+%,&&++NM--&%+,"M-"%+N+-&"&-%MH*+&""&&%&NH+&&NN

"*%-%-N%-N**--&%HN-&*%-&,*-*&---&&,*-"N%%N%*-*&-M&-M%"NH-%-*&%"",&+*&*&

&,N+M&-+-+&&%&,&---,""*,-M&+M&N+"MH%&,&+"+--+"%%N-"-&&%N"+,"M-

%,*-%M-&%N-&%-H&,",&&-"M--"%%,

%%%%%%

+ rame 2//////////////////////**,"&+"&*&*&+&,+,HH,%

++&-+&&,N***,""*M%*&M+,,++&***,"+&

,+H*&"H*+,"+,*,&*&&H-""H+*+",+H,++&&*-NH&&*&,HH*&&"H*,+H&,&H,&,&-

,%H+*H*&%*&"&*,-,*+*,&,N&*-"*&HH%"HH%+&-H"N"&+N*%-,*-M-%-*"-N&M""-N

,%&%%%%H%-&+,*+&N-,-,*&,*H&NH*&-"&"

"--%%N&N&"&%"-%H%,&NN&+HN&"*

+++M"N&,&,%"&-*+H+N&-**+"-&*"-H&,&%*H*+HN-N&&%M&*N*-*&"%"

%,%M""%M%N"%HM-+,*H&&+&&"H%"*,%%%%%%

+ rame //////////////////////,,+,%+&**,,"++,-M+*&&&&&&&&+&-+,+,%,++*,H+&&,N&H,,&N*

&-++H%MN-H&,-&,**+*%+%*H,--HN&M&%&N+*&M%%*&*,---,,----&M%&-%%&&

NM&+,%%N+N,,,&*,-&,&,-,N,-%-%N-M%%H*"*H-&N&-N+",**"M%N&-&&%%-%%&

%-"NN%"*N-%&%"H-&&*------&HH&"NN&*%N&&%%%%M"N%-"HH*N%NM%M+"&,--M-&

&&,&+&+HN&*&&,*++,--,HHH-*&&&-,HH,H,&*&--&++,-,MHH,-M&-"%"&*H&,*M&N%

*%%N-H%%"NH**N-*&H-,M*&&&NHNM%N%,,

%%%%

+ rame '"&&M&"%-%%-,**H&M--&,H&&"H&,H-&&&N&"%"&-&%H""N,&M+&+%,,

***-"N%N-%&-,-++*&****&"+%+

&HN*%%%N-"+NM,-&"""&&

*&*&&&,*"*%-*-"H"&-,&&"-N&,&-,H,&N&*%,%%,H**H+,-&N*"*

MH&N&H-""-,&,,%-**&H-N,&+&,M+HM%&"-,M&--HM*,%-,&-,,*,&

--M&+&&-M*&-",*N+&&"+&&&*-&

++-*&-*-"&&*+-H,&+H,+&++%+%%

*,***&+M"++,&,,&&&&*+,&+/////////////////////

+ rame 2

http://web.expasy.org/cgi-bin/translate/dna_sequences?/work/expasy/tmp/http/seqdna.23967,1












H&%+H*%-%,-"*+M",",HH

H&-&N&""&N*&+,*,,&"H,**H&

*,H+,H,-&&%H%%&+,,+H&"&,*&%HNH&N,,,,*&HH+++--&*%%-&+*&&%,-,-&M&H%"H,%%-

,""%,,",*-&-%&"*&*+,&-+&*&,*&"&,M*&"&",%%N&-",&-H&&+H"&-,+

H&-"--&*&&,H,*%,%*-&+,&--&HH***,*-+N%,,*"+"H*-",**H&,"***,*,*++"

&M-+,"+*+",H"H,*,,,M-*"&*+H,+*-H

,*"++H",*&*,+H"+,+M,,&&HM,*H"H,&&&&*&*+*

+,+,,&+&*,+*%,&*+HH&/////////////&//////

+ rame &--H%H,%H**%-HM,-*NM,*-&"H+"M&NN-N"&,&"H,&++H+N-&,,,,"

,+%-M&+NM%&""%-%N",H-*&,,"-*-"-++-+&%*&&%%%H*+%&H&&&H"HNNMN&&H,&

"&%*-,%N%,&,*"*%-N&*&&-&&H",&

&&,&N*+",%*""&H*+&&%H-N"&+&+M&

H,&,&+H&,&++*,H-&,-+H*"-+,&,,+

+H,"&N&*+&,,&H+H*,%,H+*,++,-,,*,++,,&HH,",&+&HHNM,&,+,+"&*,&&+*-+H,&H&+,,H+&++&+-,H&,+-,+NN&-&,,",""

&,%,H,+&&*,++**,*++,+&**&,+-&//////////////-//////

Blast





Blast Two Sequences

Prosite



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Homo Sapiens Kallikrein