Embed Size (px)
Citation preview
1) Assessment of the acute andchronic dietary risk of: 2,4-D,Glyphosate, Abamectin andThiram;
2) Proposal of mitigationmeasures, when necessary.
Dietary risk assessment in the reevaluation of pesticides at ANVISAMuratori, L.; Alves, F. N. R.; Braz, J. M.; Freitas, D. R. C.; Moreira, C. Q.
Brazilian Health Regulatory Agency (ANVISA)[email protected]
Acute and chronic dietary risk < LoC:
Theoretical condition (MRL/MAV);Real scenario - monitoring
residues in water and food.
Limitations:No data for weight and food
consumption of population < 10years old;
PARA - unspecific detection ofThiram.
Recommendations:Including the most vulnerable
part of the population in the next riskassessments;
Stewardship programs byregistrants.
Dietary risk assessment• Acute dietary exposure < ARfD• Chronic dietary exposure < ADI• Similar to other countries
Residues monitoring data (PARA)• Detection in non-approved crops
Acute exposure
ABW
97,5th
MRL/PARA*
Chronic exposure
ABW
AFI
MRL/MAV
Dietary exposure assessment
ARfD/ADI
Acute/Chronic exposure
Introduction
Methods
Objective
ConclusionResults
Risk characterization
Reevaluation: Review of the pesticidestoxicological data with potential health risksthat had not been identified at the time ofregistration.
Dietary risk assessment: systematic process to evaluate thepotential risk of short and long-term dietary intake ofpesticides residues in food.
2,4-D
Glyphosate
Abamectin
