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Outline Introduction The paper Summary Cell-pattern disordering during convergent extension in Drosophila Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB April 4, 2016 Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB Cell-pattern disordering during convergent extension in Drosophila

Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

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Page 1: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Cell-pattern disordering during convergentextension in Drosophila

Cura Costa Emanuel

SysBio Open Journal Club - IFLYSIB

April 4, 2016

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 2: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Outline

IntroductionConvergent extensionSoap bubbles in foams

The paperAuthorsFigures

Summary

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 3: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Convergent extension

I Cell-rearrangement process.

I Cell division and cell shape anisotropy independent.

I Cells interface protein enrichment.

I One-cell-thick layer.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 4: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Convergent extension

I Cell-rearrangement process.

I Cell division and cell shape anisotropy independent.

I Cells interface protein enrichment.

I One-cell-thick layer.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 5: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Convergent extension

I Cell-rearrangement process.

I Cell division and cell shape anisotropy independent.

I Cells interface protein enrichment.

I One-cell-thick layer.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 6: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Convergent extension

I Cell-rearrangement process.

I Cell division and cell shape anisotropy independent.

I Cells interface protein enrichment.

I One-cell-thick layer.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 7: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Convergent extension

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 8: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Soap bubbles in foams

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 9: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Soap bubbles in foams

Figure: Roth, A.E., Jones, C.D., & Durian, D.J.(2013). Bubble statisticsand coarsening dynamics for quasi-two-dimensional foams with increasingliquid content. Physical Review. c©2013 American Physical Society

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 10: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Authors

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 11: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Figures

Figure 1

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 12: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Figures

Figure 2

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 13: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Figures

Figure 3

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 14: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Figures

Figure 4

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 15: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Figures

Figure 5

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 16: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

I Progressive cell-pattern disordering.

I No evidence of a strongly preferred interface orientation.

I The degree of cell-pattern disordering correlates with theextent of axis elongation in the mutants.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 17: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

I Progressive cell-pattern disordering.

I No evidence of a strongly preferred interface orientation.

I The degree of cell-pattern disordering correlates with theextent of axis elongation in the mutants.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 18: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

I Progressive cell-pattern disordering.

I No evidence of a strongly preferred interface orientation.

I The degree of cell-pattern disordering correlates with theextent of axis elongation in the mutants.

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 19: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila

Page 20: Cell-pattern disordering during convergent extension in ... · Outline Introduction The paperSummary Convergent extension I Cell-rearrangement process. I Cell division and cell shape

Outline Introduction The paper Summary

Thank you very much!

Cura Costa Emanuel SysBio Open Journal Club - IFLYSIB

Cell-pattern disordering during convergent extension in Drosophila