Vision

At Fundació ACE we work so that someday

Alzheimer’s be-comes history.

Mission

Fundació ACE is an organi-zation serving people who suffer from Alzheimer’s Disease or other dementias and their caregivers.

To do so, it develops actions in the areas of diagnosis, treatment, day-

care, research, education and awareness.

Values

Commitment to people. Teamwork and interdependent work with an international pers-

pective. Pursuit of professional excellence. Promoting positive attitudes and

personal skills. Quality and rigor in the work

done.

Highlights XX anniversary of Fundació ACE.

Venue of the annual meeting of the EADC (European Alzheimer’s Disease Consortium).

The genetic biorepository reaches 10.000 samples.

The caregiver help-line, a model for the Catalan Government.

Approval of the Code of Ethics.

www. f u nd a c i o a c e. c om

Activity report 2015Executive summary

0

2000

4000

6000

8000

10000

12000

14000

16000

18000

20000

22000

24000

26000

Diagnostic Visits

Follow up Visits

Total Visits

Fig. 6 - Evolució d'actes mèdics i assistenciasl per any, 1995-2015 ( Increment quinquennal)

9707( 29%)

2,618

18,760( 93%)

5,676( 12%)

17,792( 34%)

3,490( 5%)

7,545( 18%)

11,039( 84%)

6,007( 129%)

24,436(

65%)

3,490( 5%)

2,688( 310%)

3,019( 69%)

Diagnosis is obteined through an interdis-ciplinary process that includes five visits to carry out a comprehensive

assessment and to design intervention proposals that consider the patient’s overall

needs. Specialized medical staff (neurologists, geriatricians and psychiatrists), specialists in

neuropsychology, nursing and social work comprise the multidisciplinary team that carries

out the specific evaluation of the patient.

884 patients diagnosed with Alzheimer’s Disease

Diagnostic Unit

24,436 clinical, ma-

nagement and follow-up visits

Total visits

Follow-up visits

Diagnostic visits

New patients

Follow-up patients

Total patients

Without Impairment 994 1.001 Subjective Memory Complaints 2.400 2.179

TOTAL WITHOUT COGNITIVE IMPAIRMENT 3.394 3.180

Mild Cognitive Impairment (MCI) 5.763 4.087 Other cognitive deficits due to psychiatric diseases 267 264 Déficits secundaris a malalties psiquiàtriques 151 151

TOTAL COGNITIVE IMPAIRMENT WITHOUT DEMENTIA 6.181 4.502

Alzheimer's disease 7.697 9.168 Frontotemporal Dementia (FTLD) 442 498 Vascular Dementia (VD) 1.227 1.496 Lewy body Dementia (LBD) 564 669 Other neurodegenerative dementia 18 17

TOTAL DEMENTIA 9.948 11.848

Others 47 44 Unfinished withdrawals and deceded 150 146

TOTAL UNFINISHED 197 190

TOTAL 19.720 19.720

WITHOUT COGNITIVE IMPAIRMENT CDR 0

COGNITIVE IMPAIRMENT WITHOUT DEMENTIA CDR 0,5

Tipology of Diagnosis Initial diagnosis Final diagnosis

COGNITIVE IMPAIRMENT WITH DEMENTIA CDR 1, 2, 3

UNFINISHED

19,720people diagnosed

since 1995

478patients have changed to a

diagnosis of de-mentia in 2015

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

1996

1998

2000

2002

2004

2006

2008

2010

2012

2014

CTs 1996-2015

Started in previous years

New in the year

Total active CTs

Research Unit

10,103genetic samples

Fundació ACE has created a digital database with informa-tion on more than 19,000 anonymous individuals. It has

developed tools for extracting systematic clinical data and has collected samples from over 10,000 people

to extract and analyze their DNA. This collection of genetic material and its associated patient data is the most extensive

in our country and one of the largest in Europe.

151.04 is the impact

factor of the 19 articles published

in 2015

22clinical trials ca-rried out in 2015

This biorepository, together with the expertise of Fundació ACE’s professio-nals, has lead to significant collabora-tions with major international consortia

related to genetic studies on aging. The Fundació is a partner in the transat-lantic international consortium NEU-

ROCHARGE 2 and in the meta-GWAS IGAP project (International Genomics

of Alzheimer’s Project) and the national consortium DEGESCO.

Alzheimer; 500; 36%

Mild Cognitive Impairment;

400; 29%

Healthy Controls; 200; 14%

Vascular Dem.; 100; 7%

Subjective Cognitive Decline; 50; 3%

Other dementias; 50; 4%

FTLD*; 50; 4%

Under diagnostic process; 40; 3%

Fig. 8 - Tipologia del Banc de Mostres Genètiques 2005-2015Total Mostres:

*FTLD: Fronto temporal lobar dementia

Fig. 8 - Tipologia del Banc de Mostres Genètiques 2005-2015Total Mostres:

*FTLD: Fronto temporal lobar dementia

Typology of the samples

Alzheimer; 31; 53%

Mild Cognitive Impairment; 20;

34%

Vascular Dem.; 2; 3%

Mixed Dem.; 4; 7%

Frontotemporal Dem.; 2; 3%

www. f u nd a c i o a c e. c om

Day Care Centre (DCC) is aimed at people with Mild Cognitive Impairment and / or dementia. The centre has capacity for 80 users.

Day Care Hospital (DCH) is aimed at people with Mild Cognitive Impairment and / or dementia, primarly under 65. The hospital has capacity for 75 users.

The attention is personalized in small groups, which are determined by the

cognitive state.

Memory workshops (MW) are aimed at people with Mild Cognitive Impairement

and / or early stages of dementia. They have capacity for 80 participants.

The aim of the Day Care Unit is to provide continuous therapeutic care in cognitive, physical, psychological and social, through the Program of Integral Psychostimulation (Tárraga L. &

Boada M. 1990). The person with cognitive impairment and / or dementia and their family take advantage of a comprehensive thera-peutic care with an interdisciplinary approach to meet their needs at

early and moderate stages.

Day Care Unit

Memory workshops users since 1988

Total users of the Day Care UnitDCC & DCH users

251Day Care Centre and

Day Care Hospital users in 2015

59 users of the me-mory workshops; 31 of them with a

diagnosis of Alzhei-mer’s disease

85

156

299

251

35

83 72 59

1843

120

239

371

310

0

50

100

150

200

250

300

350

400

450

Total HD & CD Usuaris U.M. (des de 1998) TOTAL Usuaris UAD

Total HD & CD Usuaris U.M. (des de 1998) TOTAL Usuaris UAD