483483483

Mindolli et al., Int J Med Res Health Sci. 2015;4(3):483-485

DOI: 10.5958/2319-5886.2015.00093.4

International Journal of Medical Research&

Health Scienceswww.ijmrhs.com Volume 4 Issue 3 Coden: IJMRHS Copyright @2014 ISSN: 2319-5886Received: 25th Oct 2014 Revised: 10th Nov 2014 Accepted: 13th Nov 2014Research article

SEROPREVALENCE OF HEPATITIS B IN A TERTIARY CARE CENTRE IN BIJAPUR,KARNATAKA: A TWO YEARS PROSPECTIVE STUDY

*Preeti B. Mindolli1, Manjunath P. Salmani2

1Associate Professor, Department of Microbiology, Al Ameen Medical College, H &RC, Athani Road, Bijapur,Karnataka, India.2Associate Professor, Department of Microbiology, SBMP Medical College, H &RC, Solapur Road, Bijapur,Karnataka, India.

*Corresponding author email: drmindolli@rediffmail.com

ABSTRACT

Background: Hepatitis B virus infection is endemic throughout the world especially in tropical and developingcountries. Clinical data collected in the hospital gives the estimation of burden of disease in the community aspatients with different background attend the hospital. With this background the present study was designed. It isa prospective study estimating the prevalence of HBV infection in a tertiary care centre. Objective: Study wasconducted to know the prevalence of hepatitis B virus infection in a tertiary care centre in Bijapur, Karnataka.Methodology: Patients attending Out-Patient Department (OPD) and In-Patient Department (IPD) with variousdiagnosis who were advised for HbsAg testing were included in this study. Immunochromatographic method(Hepacard) was used for qualitative detection of HbsAg to diagnose HBV infection. Results: A year wiseseropositivity showed there was slight increase in the HBV positive cases. In 2012 prevalence rate was 1.54% andin 2013 it was 1.65%. Male preponderance compared to females was seen. More number of cases was seen inactive age group i.e. 31-40 years. Conclusion: The present study shows there is slight increase in number of casesin 2013 compared to 2012. This study also highlights that hospital based studies can be an option for communitybased studies.

Keywords: Hepatitis B; Immunochromatography; Seroprevalence

INTRODUCTIONHepatitis B virus (HBV) is common human pathogenand causes acute and chronic liver disease throughoutthe world. Chronic illness develop in 5-10% 0finfected adolescents or adults and up to 90% ininfected neonates. Chronic HBV infection is a major

cause of liver cirrhosis and primary cell carcinoma.[1]

Hepatitis B is endemic throughout the world,especially in tropical and developing countries andalso in some regions of Europe. Its prevalence variesfrom country to country and depends on behavioral

environment and host factor.[2]

More than two billion people worldwide haveevidence of past or current HBV infection and 350million are chronic carriers of the virus, which isharbored in liver and causes an estimated 6, 00, 000deaths from cirrhosis of liver and hepatocellular

carcinoma.[3]

In Middle East and Indian subcontinent, an estimated2-5% of general population is chronically infectedand falls in intermediate category according to WorldHealth Organization (WHO) classification.[2,3]