Winnie Svendsen, DTU

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Prsentationen blev holdt ved InfinIT-konferencen SummIT 2013, der blev afholdt den 22. maj 2013 p Axelborg i Kbenhavn. Ls mere om konferencen her: http://www.infinit.dk/dk/arrangementer/tidligere_arrangementer/summit_2013.htm

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  • 1. www.nanotech.dtu.dk/nabisPoint-of-Care devicesWinnie E. SvendsenDTU Nanotech

2. www.nanotech.dtu.dk/nabisPoint of Care - Healthhttp://www.continuaalliance.org/about-the-alliance 3. www.nanotech.dtu.dk/nabisPoint of Care Healthhttp://health.rush.edu/HealthInformation/Care%20Guides/28/000278.aspx 4. www.nanotech.dtu.dk/nabisPoint of Care TechnologyRef: Center for Bio photonics Science and technology University of California 5. www.nanotech.dtu.dk/nabisPoint of Care EnviromentVandforurening i KalundborgBrnehave ramt af vandforurening p tredje ugeUdgivet den 02.01.2013 21:18Advarsel: Drik ikke vandet i KBHFredag d. 19. aug. 2011 kl. 17:11201320122011Stadig forbud mod brug af vand i centrum af KalundborgUdgivet den 20.12.2012 21:09 af TV2 STs Redaktion 6. www.nanotech.dtu.dk/nabisPoint of Care EnviromentThe Law : Lab test 30 test per year 72 hours response time 7. www.nanotech.dtu.dk/nabisNano Bio Integrated Systems (NaBIS )2012Micro and NanoSensor PlatformsMicrofluidic Sample handlingand manipulationBio MedicalApplicationsOur vision is to incorporate our research in point of care(POC) technology for diagnostic and monitoring.This is achieved by application-driven research, adaptingand refining methodologies to micro- and nanotechnologywithin bio-medical fields 8. www.nanotech.dtu.dk/nabisNano Bio Integrated Systems (NaBIS )Micro and NanoSensor PlatformsBio MedicalApplicationsMicrofluidic Samplehandling and manipulation 9. www.nanotech.dtu.dk/nabisPoint of Care SensorsMicro and NanoSensor PlatformsBio MedicalApplicationsMicrofluidic Samplehandling and manipulation 10. www.nanotech.dtu.dk/nabisPoint of Care Sensors 11. www.nanotech.dtu.dk/nabisNano Bio sensors - HealthBiomedical engineering for cancerand brain disease diagnosis andtherapy developmentA screenning system for Theplasmacytosis virus in Minkhttp://www.engcabra.eu 12. www.nanotech.dtu.dk/nabis64 chips4 SiNW on one chipThe Silicon Nano Wires Sensor300 nmSiNWh= 50 nml = 200 mw= 50 m 13. www.nanotech.dtu.dk/nabisSiNWh= 50 nml = 200 mw= 50 mAzeem Zulfigar 14. www.nanotech.dtu.dk/nabisSemiconducting Nanowire Sensor++AcceptorsHoles (mobile)=> Get a chage in conductance (DG/G)+++ ++- - -Receptors binding a target molecule (negative)Know and can control charge carriers in the wire 15. www.nanotech.dtu.dk/nabisSilicon Nanowire BiosensorNanowireAdd a functional layerMultiple functional layers 16. www.nanotech.dtu.dk/nabisSilicon Nanowire Biosensor 17. www.nanotech.dtu.dk/nabisSiNW sensor for Aleutian Disease Virus (ADV)Integration of Silicon Nanowires in Microfluidic Devices 18. www.nanotech.dtu.dk/nabisSiNW sensor for Aleutian Disease Virus (ADV)Aleutian Disease or Mink Plasmacytosis is a highly contagiousparvovirus affecting the animals, causing spontaneousabortion and death in minks and ferrets.ADV smallest virus existing d~7 nmTask : Screen blood samples for antibodies 19. www.nanotech.dtu.dk/nabisImmobilization of whole virusGoal : Attach the dead virus on the surfaceDetect antibodies in the animal sampleAPTES 20. www.nanotech.dtu.dk/nabisTest Functionalisation SchemeImmobilization results12 hours withoutlight3 hours with PH3CBF4Conclusion:1.High selectivity2.High Yield3.The catalysts worked asplanned12 hourswith light 21. www.nanotech.dtu.dk/nabisScreening for ADV virus in Minks sampleLars AndresenKU Sund 2010 22. www.nanotech.dtu.dk/nabisMichael Jrgensen MscMartin H. Srensen MScIntegration of Silicon Nanowires in Microfluidic Devices 23. www.nanotech.dtu.dk/nabis www.nanotech.dtu.dk/nabisFully automated system 24. www.nanotech.dtu.dk/nabisPOCT Screening of CancerBiomedical engineering for cancerand brain disease diagnosis andtherapy developmentCA9 NKG2D ligands 25. www.nanotech.dtu.dk/nabisFunctionalisation SchemeAPTESAndreaDTULarsKU Sund 26. www.nanotech.dtu.dk/nabisMouse Antibody Goat Antibody interaction 27. www.nanotech.dtu.dk/nabisSample HandlingAndrea PfreundtDTU Nanotech 28. www.nanotech.dtu.dk/nabisSystem Engineering/ Embedded SystemsJan MadsenDTU ComputeFrancois PatouDTU NTCH 29. www.nanotech.dtu.dk/nabiswww.nanotech.dtu.dk/nabisAcnowledgementsPeople NaBISFundsCollaboratorsDTU Nanotecth Mads BrandbygeKristian MlhaveKU-life Sren SchouLars AndresenFranziska , Phd studentDTU Farma se UttenthalDPA Leif BruunRebekka Dam-Tuxen, Phd Stud.iSAS Slovakia Prof. Silvia PatrokovaDTU Compute Prof. Jan Madsen