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Diagnostic Cartridges
Diagnostics Sample Handling Devices
Life Science Cartridges
Microfluidic Devices
Medical Devices
Drug Delivery Systems
Medical Diagnostics
Angioplasty
Ophthalmology
Dental Products
Respiratory Products
Other High Volume Medical Products
Diagnostic cartridges
single test strip, multiple
test strip and specialty
housings.
SLA prototypes to verify
fluidic function.
Fabricated prototype
tooling for clinical
studies, internal testing.
Coordinated design
transfer to manufacturing.
Mechanical Product Design
Industrial Design
3D Solid Modeling (Solidworks)
Microfluidic Device Design
Precision Prototype Machining
Rapid Prototype Tooling and Molding
LIM Silicone Molding
Product Testing and Test Method Development.
Failure Modes and Effects Analysis (FMEA)
Process Development
Manufacturing Transition
Product Reliability Assessment
Coming up with creative concepts to
meet your requirements.
Rapidly
Identifying, prototyping, testing and
verifying high risk functions.
Replicating scalable manufacturing
processes early in the development
process.
Seamlessly transferring the product
to production.
All of the above
Fully equipped engineering LabUltrasonic welding, UV Bonding, Heat
sealing – all in house.
Custom Test Method DevelopmentInspection and Imaging
DCN Symbiosis Combination of Engineering (Device) and Science (Assay) Development for diagnostic products.
Converting/Lamination We collaborate with companies such as Aline and others on microfluidic fabrication methods outside our internal capabilities.
Instrument Developers Collaborated with instrument development houses including Qiagen (ESE), LRE and BIT Group (Source and CalMedtech). Separation of instrument and disposable results in optimized design solution.
Contract Manufacturers: Strong partnership with a variety of contract manufacturers for high volume medical products such as HK Plastics.
MF3: Technology Member.
Example
Provided design and
fabrication expertise to Dr.
Elliot Hui for proof of concept.
Revised design and fabricated
oscillator chip and verified
equivalent function vs. glass
etched units.
Analyzed design for molding
and confirmed ability to
produce parts with low cost
injection molding.
Developed test method to
visualize and characterize flow
uniformity.
Developed fixture to evaluate
various configurations and
pressures and evaluate impact on
flow.
Product
DXNA Molecular Diagnostic Cartridge.
Challenges
Device leaked during operation.
Assembly process was expensive and unreliable.
Process
Symbient Redesigned device to optimize fluidics and utilize ultrasonic welding process.
Integrated hydrophobic vent material.
Fabricated prototype tooling/Developed ultrasonic and laser welding methods in house.
Result
Solved leakage problems.
Reduced manufacturing cost and improved reliability.
Transferred product to contract manufacturer.
Product
BD Veritor Cartridge and Sample Handling Device.
Challenges
Develop a CLIA Waived Flu A/B test.
Process
Worked closely with customer to develop precise
cartridge with intuitive instrument interface.
Worked closely with customer to develop user
friendly sample delivery system.
Worked closely with contract manufacturers to
rapidly transfer tooling and assembly processes
from development to high volume manufacturing.
Result
Achieved CLIA waived status
Seamlessly transferred molding to contract
manufacturer.
www.symbientpd.com
Contacts:
Erica [email protected]
John [email protected]
Symbient Product Development1061 La Mirada Court
Vista CA 92081Phone: 760 687 4030
