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Bellringer List an example of an acid or base you are familiar with in everyday life. What do you know about the pH scale?

Biochem 3: pH & proteins

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Page 1: Biochem 3: pH & proteins

Bellringer

List an example of an acid or base you are familiar with in everyday life.

What do you know about the pH scale?

Page 2: Biochem 3: pH & proteins

AgendaCollection Time

Book Project & Macromolecule notesCandy Molecules lab

Quick Experiment: Milk and Vinegar

Guided Notes: pH & the Effect on ProteinCompare Acids and BasesReview the use of pH scaleDescribe how changes in pH affect proteins

Page 3: Biochem 3: pH & proteins

Properties of Acids

Sour taste

Corrosive to metals

Burns the Skin

Page 4: Biochem 3: pH & proteins

Examples of Acids

Acetic Acid in Vinegar

Citric Acid in Oranges and Lemons

Hydrochloric Acid dissolves food in your stomach

Page 5: Biochem 3: pH & proteins

Properties of BasesBitter Taste

Feel “Soapy”

Will irritate your skin

Page 6: Biochem 3: pH & proteins

Examples of Bases

Milk of Magnesia

Bleach

Many Soaps

Page 7: Biochem 3: pH & proteins

Acid/Base Chemistry

Acids release Hydrogen ions [H+] when mixed with water.

Bases absorb Hydrogen ions [H+] when mixed with water.

Page 8: Biochem 3: pH & proteins

Neutralizations

Since Acids produce [H+] and Bases absorb [H+], it is possible for acids and bases to cancel one another.

When acids and bases cancel out it is called Neutralizing

Page 9: Biochem 3: pH & proteins

pH Scale

The strength of Acids and Bases is measured using the pH scale

Scale goes from 0 to 14ACIDS = below 7NEUTRAL = exactly 7BASES = above 7

Page 10: Biochem 3: pH & proteins

pH and Strength

The further an acid or base is from 7, the stronger it is.

ExamplesLemon Juice (2.0) is a stronger acid than

Beer (4.0) because a pH of 2 is farther from 7.

Ammonia (11.0) is a stronger base than Baking Soda (8.3) because a pH of 11 is farther from 7.

Page 11: Biochem 3: pH & proteins

BrainPOP: Acid/Base

Page 12: Biochem 3: pH & proteins

Protein Folding

Proteins are long chains of amino acids.

These chains bend and fold into a certain shape that allows them to perform their job.

The shape of the protein is held together by bonds between amino acids on different parts of the chain.

Page 13: Biochem 3: pH & proteins
Page 14: Biochem 3: pH & proteins

Protein Structure Video Clip

Page 15: Biochem 3: pH & proteins

How Acids Denature Proteins

Acids destroy proteins by “denaturing” them. This means that the protein gets unwrapped and the shape is destroyed.

Acids can unwind proteins because the H+ [Hydrogen ions] interfere with the bonds that hold the protein together.

For this reason, it is important for living things to maintain a consistent pH level in bodily fluid. For example, human blood must stay at a pH of 7.4

Page 16: Biochem 3: pH & proteins

H+

H+

H+

H+

H+

Page 17: Biochem 3: pH & proteins

Explain what caused the milk to curdle. . .

Page 18: Biochem 3: pH & proteins

Assignments

12 Review Questions

Using pH to identify liquids

Students should complete their Quarterly Assessment if not finished yesterday.