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Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

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International Conference on Applied Statistic 2013 | 16 – 18 September 2013 | Bandung, Indonesia.

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Page 1: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia
Page 2: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Methods

Result & Discussion

Conclusion

Reommendation

Page 3: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia
Page 4: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Page 5: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Page 9: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Research Question

How do the prevalence of diabetes

influence the prevalence of stroke

in Indonesia’s province, given each

province has constant prevalence

of hypertension ?

Page 10: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Methods

Result & Discussion

Conclusion

Recommendation

Page 11: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

What is the study design?

Page 13: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource:

Data Resource: http://labmandat.litbang.depkes.go.id/

Page 14: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Page 15: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Page 16: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Page 17: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Page 18: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Prevalence of

Stroke

Page 19: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Prevalence of

Diabetes

Prevalence of

Stroke

Page 20: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data collected?

Data Resource: http://labmandat.litbang.depkes.go.id/

Prevalence of

Diabetes

Prevalence of

Stroke

Prevalence of

Hypertension

Page 21: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data analyzed?

Statistical Tool & Model

Page 22: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data analyzed?

Y : prevalence of stroke

X : prevalence of diabetes

X : prevalence of hypertension

i

1i

2i

Statistical Tool & Model

Page 23: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data analyzed?

Y : prevalence of stroke

X : prevalence of diabetes

X : prevalence of hypertension

i

1i

2i

Statistical Tool & Model

E(Y |X , X ) = βX + βX + α (constant) + ɛ (residual error) 1i 2i 1i 2i i

Page 24: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

How is the data analyzed?

Y : prevalence of stroke

X : prevalence of diabetes

X : prevalence of hypertension

i

1i

2i

Statistical Tool & Model

STATA ®12

E(Y |X , X ) = βX + βX + α (constant) + ɛ (residual error) 1i 2i 1i 2i i

Page 25: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Methods

Result & Discussion

Conclusion

Recommendation

Page 26: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Regression Assumption

Page 27: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Regression Assumption

1) Independent observation

Page 28: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Regression Assumption

1) Independent observation

2) Linear relationship

Page 29: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Regression Assumption

1) Independent observation

2) Linear relationship

3) Homoscedasticity (constant variance)

Page 30: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Regression Assumption

1) Independent observation

2) Linear relationship

3) Homoscedasticity (constant variance)

4) Y | X, is normaly distributed

Page 31: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Peason’s correlation analysis

Page 32: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000).

2

Page 33: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000).

2

Adj-R = 0.35 2

Page 34: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000).

Y : prevalence of stroke i

2

Adj-R = 0.35 2

Page 35: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000).

Y : prevalence of stroke i

X : prevalence of diabetes 1i

2

Adj-R = 0.35 2

Page 36: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

Regression fit Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000).

Y : prevalence of stroke i

X : prevalence of diabetes 1i

X : prevalence of hypertension 2i

2

Adj-R = 0.35 2

Page 37: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

95% CI Regression fit

Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000). The increase was estimated to be 4.45% (95% CI from 2.31% -

6.59%) per 1 % increased of prevalence of diabetes,

2

Adj-R = 0.35 2

Page 38: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

510

15

20

.5 1 1.5 2 2.5Prevalence of Diabetes

95% CI Regression fit

Prevalence of Stroke

Pre

va

len

ce

of

str

ok

e

Prevalence of diabetes

r = 0.61 (p < 0.001)

Multivariate linear regression

E(Y | X ,X ) = 6.11 + 4.45 X - 0.083X + ɛ ~N (0, 2.5 ) 1i 2i 1i 2i i

Prevalence of stroke increased significantly with prevalence of diabetes

(t(30) = 4.25 ,p=0.000). The increase was estimated to be 4.45% (95% CI from 2.31% -

6.59%) per 1 % increased of prevalence of diabetes, given controlling prevalence of

hypertension (within province has constant prevalence of hypertension).

2

Adj-R = 0.35 2

Page 39: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Background

Methods

Result & Discussion

Conclusion

Recommendation

Page 40: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia
Page 41: Province-level analysis using multivariate linear regression model for predicting the impact of diabetes on prevalence of stroke in Indonesia

Thank you