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HOW CELLS EXPORT PROTEINS IN THE MEMBRANE AND RESEARCHERS
VISUALIZA OCURRING mRNA
María Camila Foronda Campuzano
Medicine Student
FOLDING
FOLDING
INTRODUCTION
The structure of a ribosome complex involved in a protein
process
By a wonderful technique they vizualized mRNA and
associated molecules
How Cells Export And Embed Proteins In The Membrane ScienceDaily (January 3, 2001)
How Cells Export And Embed Proteins In The
Membrane The
ribosomes found on the RE fabric proteins that are export outside cell
The proteins move from the ER and accumulated near the Golgi apparatus and
How Cells Export And Embed Proteins In The Membrane
The Proteins are "eliminated" from membrane in vesicles by channels
How Cells Export And Embed Proteins In The Membrane
• Transduction of external signals produces a response from the target cell
• This response is impaired as a result of activation or inhibition of a metabolic pathway
How Cells Export And Embed Proteins In The Membrane
• An international team of researchers to find another mystery related to the ribosomes - the enigmatic jumbles of molecules
• the journal Nature, could help in developing new antibiotics to combat multi-resistant superbugs such as MRSA(methicillin-resistant Staphylococcus aureus infection) found inmany U.S. hospitals
ANOTHER STUIDES…
OBSERVATION
This investigacions raises that the
complex ribosome-
protein and the receptor act as a
«switch», so it can stop
They raises to that it more
studies productions of proteins
can be controled
It could indicated
to the stop of many
deseases
In Scientific First, Researchers Visualize Naturally Occurring mRNAScienceDaily (Jan. 19, 2011)
In Scientific First, Researchers Visualize Naturally Occurring mRNA
• Messenger RNA, the key intermediary in gene expression, translating the DNA's genetic code into the amino acids that make up proteins
In Scientific First, Researchers Visualize
Naturally Occurring mRNA
• There are 20 amino-acids forming sub-units for proteins while only four nucleic bases are used to construct the RNA or DNA
In Scientific First, Researchers Visualize Naturally Occurring mRNA
• The mature mRNA is transported to the cytoplasm of the cell, in the case of eukaryotes beings through nuclear membrane poresMessenger RNA in the cytoplasm is coupled to the ribosomes
In Scientific First, Researchers Visualize Naturally Occurring mRNA
• mRNA are the machinery responsible for protein synthesis.After a certain amount of time the mRNA is degraded into its component nucleotides, usually with the assistance of ribonucleases
OBSERVATION
It is an important
study because they are in the way to control
gene expressions
This control can cure
many desease with
genetic origin
It is a useful
technique to
monitored mRNA
MEDICAL UTILITY
MEDICAL UTILITY
Both studies can be very benefical for discover deseases and try to find a cure for it, because molecular biology is basis of all functions of our bodies
BIBLIOGRAPHY
• MARTINEZ S, Lina Maria. Biologia Molecular. 6 ed. Medellin. UPB. Fac Medicina, 2011. 34p.
• ScienceDaily, Your source for the latests research news, United States.[Index].