NURS 1566 Clinical Form 3: Clinical Medications Worksheets(You will need to make additional copies of these forms)

Generic NameOndansetron

Trade NameZofran

Classificationantiemetic

Dose4 mg

RouteIVP

Time/frequencyPRN nausea

Peak15-30 minutes

OnsetRapid

Duration4-8 hrs

Normal dosage range4 mg to preventing

Why is your patient getting this medicationNausea/Vomiting

For IV meds, compatibility with IV drips and/or solutionsD5W, 0.9% NaCl, D5/0.9% NaCl, D5/0.45% NaCl. Solution is clear and colorless. Stable for 7 days at room temperature following dilution. Administer each dose as an IV infusion over 15 min

Mechanism of action and indications(Why med ordered)Blocks the effects of serotonin at 5-HT3 receptor sites (selective antagonist) located in bagal nerve terminals and the chemoreceptor trigger zone in the CNS.Indicated for prevention of nausea

Nursing Implications (what to focus on) Contraindications/warnings/interactions.Contraindicated in hypersensitivity. May be affected by drugs that alter liver enzymesCommon side effectsHeadache constipation and diarrhea.

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically)None

Lab value alterations caused by medicineMay cause transient increase in serum bilirubin, AST, and ALT levels.Be sure to teach the patient the following about this medicationNotify physician immediately if involuntary movement of eyes face or limbs occur.

Nursing Process- Assessment(Pre-administration assessment)assess pt for nausea, vomiting, abdominal distention, and bowel sounds

AssessmentWhy would you hold or not give this med?If pt is experiencing extrapyramidal effects (involuntary movements, facial grimacing rigidity, shuffling walk, trembling of hands)

EvaluationCheck after givingPrevention of nausea.