November 1, 1992

Aamdal, S., 6088Abe, T., 6083Akao, Y., 6083Anwar, K., 5991Arredondo, M. A., 5900Azzarone, B., 5963

Baker, P. D., 5893Balfe, J. W., 6125Benedetti, M. S., 5933Bennett, W. P., 6092Berger, D. P., 5940Bermudez,E.,6113Bhorjee, J. S., 6129Bickers, D. R., 6106Blaese, R. M., 6020Blumenthal, R. D., 6036Boffa, L. C., 5906Bontenbal, M., 6101Boven, E., 5940Bowden, P. E., 5865Braakhuis, B. J. M., 5940Brandt, S., 6020Brent, T. P., 6052Bruland, 0. S., 6088Bryce, W. H., 5853Bu, D., 5985Buettner, G. R., 6045Burns, C. P., 6045Burrows, F. J., 5954Bystryn, J-C., 5948

Callen, D. F., 6117Cariani, C. T., 6079Casey, G., 5997Cass, C. E., 5879Ceppi, M., 5906Chen, A., 5971Chen, D-S., 6098Chen,Z., 6113Cheng, K. H., 6066Chou, H-C., 6098Chung, J-C., 6098Coale, M. M., 6020Coombes, R. C., 5933Coppes, M. J.,6125Croce, C. M., 6110Cuadrado, M. A., 5979

Damsky, C. H., 6001Delgado, M. D., 5979Della Porta, G., 6079de Witte, T., 5921DiPaolo, J. A., 5865Di Salle, E., 5933Domach, M. M., 6010Donghi, R., 6079Doniger, J., 5865Douglass, E. C., 6117Dumont, M. P., 5940

Elmets, C. A., 6106Eskey, C. J., 6010Evans, C. H., 5893Evans, T. R. J., 5933

Faras, A. J., 5872Fiebig, H. H., 5940Finley, G. G., 5853

Finn, 0. J., 5985Fischer, R., 6110Fisher, S. J., 6001Flørenes,V. A., 6088Fodstad,0.,5940,6088Foekens, J. A., 6101Fong, C-J., 5887Fontana, A., 6121Foshag, L. J., 6059Furmanski, P., 6129

Geiser, C. F., 6117Ghai, J., 5872Giorda, R., 5913Goldenberg, D. M., 6036Gomella, L. G., 6110Gomez-Casares, M. T., 5979Gonzaga, P. E., 6052Gross, E. A., 6113Guimaraes, M. A., 5900

Haag, M., 5926Harris, C. C., 6092Haywood, L., 6036He,A.,6092Henn, M., 5948Heo, D. S., 5963Herberman, R. B., 5913, 5963Hernandez, M., 6066Higuchi, M., 6125Himmelmann, A., 6121Hollstein, M. C., 6092Hoon, D. S. B., 6059Huang, G-T., 6098Huff, V., 6117

lida, S., 6083Inazawa, J., 6083

Incognito, L. S., 5997Inuzuka, M., 5991Itzkowitz, S. H., 5971

Jam, R. K., 6010Jänicke,F., 6101Janowska-Wieczorek, A., 5879Jerome, K. R., 5985Johnson, J. T., 5963Jones, M. 0., 5853

Kennel, S. J., 6036King, K. M., 5879Klijn, J. G. M., 6101Koretsky, A. P., 6010Koski, R. A., 5853Kozlowski, J. M., 5887Kusters, I., 6092Kvols, L., 6074

LaBresh, K., 5872Lai, M-Y., 6098Lane, D. P., 6092Langdon, S., 5940Lassus, M., 5933Lee, C., 5887Lee, H-S., 6098Lee, P-H., 6098Lenoir, G., 6117Leon, J., 5979Leppert, M., 6117Levy, A. T., 6020

Li, F. P., 6117Li, J., 5948Liefers,G.J.,6125Lin, R. T., 6059Lin, W-c., 5963Liotta, L. A., 6020Lipkin, M., 5906Logan, S. K., 6001Lopez, M. E., 5997Lottering, M-L., 5926Ludlum, D. B., 6052Lupton, J. R., 5906

Maelandsmo, G. M., 6088Malipiero, U., 6121Margison, G. P., 6052Mariani, M. R., 5906Martinez, C. A., 5979McGlennen, R. C., 5872Meadows, A., 6117Meisler, A. I., 5853Melhem, M. F., 5853Mendelsohn, J., 5887Merrick, M. A., 5997Metcalf, R. A., 6092Miozzo, M., 6079Monne, M., 6110Montaño,J. T., 5879Moreno, J. G., 6110Morgan, K., 6113

Morisaki, T., 6059Morton, D. L., 6059Mukhtar,H.,6106Mulholland, S. G., 6110Mullen, C. A., 6020Myklebost, 0., 6088

Naiki, H., 5991Nakakuki, K., 5991Nakazawa, S., 6083Natale, A. M., 6036Neilson, E. G., 6129Newmark, H. L., 5906Niu,T-q.,6052

Ogata, S., 5971Ornati, G., 5933Osteaux, M., 6025Ostrow, R. S., 5872

Padarathsingh, M., 6129Pastorino, U., 6079Peters, H. A., 6101Pianezzola, E., 5933Pierotti, M. A., 6079Pilotti, S., 6079Pipas, J. M., 5853Plaisance, S., 5963Pluta, L., 6113Potter, P. M., 6052Preijers, F. W. M. B., 5921

Qin, Y., 6025Quincoces, A. F., 5979

Rafferty, J. A., 6052Recio, L., 6113Reeve,A.E.,6117Resau, J. H., 6092Reubi, J-C., 6074

Richard, C., 5979Rozengurt, E., 6031Rustum, Y. M., 5900

Sacchi, M., 5963Saunders, G. F., 6117Scalmati, A., 5906Schally, A. V., 6025Schechter, G. L., 5997Schmitt, M., 6101Schneider, J. F., 5872Schreiber, E., 6121Seegers, J. C., 5926Sethi, T., 6031Seto, M., 6083Sharkey, R. M., 6036Sherwood, E. R., 5887Sheu, J-C., 6098Shih, L-N., 6098Shiraishi, T., 5991Shroba, S., 5948Siegel, J. A., 6036Sisk, S., 6113Somers, K. D., 5997Sozzi, G., 6079Stahel, R., 6121Stetler-Stevenson, W. G., 6020Strong, L. C., 6117

Takahashi, T., 6083Thorpe, P. E., 5954Tobler, A., 6121Tribby, I. I., 5853Trucco, M., 5913Trump, B. F., 6092

Ueda, R., 6083Uehara,H.,5971

Van Cauteren, M., 6025van Oosterhout, Y. V. J. M.,

5921van Putten, W. L. J., 6101Vihko, P., 6110

Wagner, B. A., 6045Walker, C., 6113Wang, J-T., 6098Wang, T-H., 6098Watanabe, Y., 5954Weidmann, E., 5913, 5963Welsh, J. A., 6092Wessels, H. M. C., 5921Whiteside, T. L., 5913, 5963Willems, G., 6025Williams, B. R. G., 6125Winograd, B., 5940Wong, G. Y., 6036Woodworth, C. D., 5865Yamamoto, K., 6083Yang, P-M., 6098Yasumura, S., 5963Yatani, R., 5991Yin, M-b., 5900Yu, D., 6052Yuzuki, D. H., 6059Zaidi, S. I. A., 6106Zhang, Z-g., 5900Zhu, S-rn., 6092Zinn, A. B., 6125

6138

AUTHOR INDEX

2. 5 copies of the candidate's most current curriculum vitaeand bibliography.

3. 5 copiesof a letterof recommendationfrom a nominatorwho is an active,emeritus,or honorarymemberof theAACR(atleastonecopymustbeasigned,originalletter).This letter shoulddescribethe candidate'sachievementsin laboratoryresearch,clinicalinvestigations,or epidemiologicalresearch,and it shouldaffirm that this researchadheresto acceptedethicalstandards.—OR—Thenominatormaysupplythe responsesrequestedat the bottomof the application form in the section entitled “STATEMENTOFSUPPORT―(at leastonecopyof the formmustbe the signedoriginal).

4. 5 copies of a letter of recommendation as described inItem 3 above from a seconder who is an active, emeritus,or honorarymemberof theAACR(at leastonecopymustbe a signed, original Ietter).—OR—Thesecondermaysupply the responses requested at the bottom of theapplication form in the section entitled “STATEMENTOFSUPPORT―(at least one copy of the form must be thesignedoriginal).

5. 5 reprintsof each of two publicationson whichthe candidateappearsas author.

Allmaterialshouldbecollatedinto fivecompletesetswith theoriginal application form as a covering document and sent to theaddressgivenbelow.Questionsregardingproceduresfor membershipapplicationmayalsobedirectedto thefollowingaddress:

American Association for Cancer ResearchPublic Ledger Building

620 Chestnut St.Suite816

Philadelphia,PA 19106-3483215/440-9300

RESPONSIBILITIESOF MEMBERSHIP

Candidatesshouldbe awareof the followingresponsibilitiesof membershipin the AACR.Activemembersmust pay annualdues,a majorportionof which is designatedfor a subscriptionto at leastoneof the AACR'spublications.Newlyelectedmembersof the AACRwho havealreadypurchasedsubscriptionstoCancerResearch,CellGrowth& Differentiation,or CancerEpidemiology,Biomarkers& Preventionat the higher,nonmemberrate will receivereimbursementof the unusedportionof thosesubscriptionsonce their first year's membershipdues are paidin full.

All correspondingmemberselectedafter May 23, 1985, arerequired to pay an annual assessment in lieu of dues. Thisassessment,which is equivalentto that portion of the regularduesthatpertainsto supportof activitiesotherthanpublications,is imposed to defray the cost of sending AACR publications to

membersoutsidethe Americas.Correspondingmembersmay,if they wish, subscribeto Cancer Research,Cell Growth &Differentiation,or CancerEpidemiology,Biomarkers&Preventionat the reducedmemberrate.

Applicantselectedin May will be responsiblefor paymentofthatyear'sdues;applicantselectedinSeptemberandDecemberwillpayduesin thefollowingyear.Applicantselectedin MayandSeptemberwill be eligibleto sponsoran abstract for the nextannualmeeting.Everyeffort will be made to afford the sameopportunityto applicantselectedin December.

MargaretFotiExecutiveDirector

,@ AMERICAN ASSOCIATION FOR CANCER RESEARCH

:@@

. \\@@@) ,@ GUIDELINES FOR APPLICATION FOR ACTIVE AND

\@@$ CORRESPONDINGMEMBERSHIP

BENEFITS OF MEMBERSHIP

The AmericanAssociationfor CancerResearch(AACR)is ascientific society consisting of laboratory and clinical cancerresearchers. It was founded in I 907 “tobring together activeinvestigatorsof the cancerproblemfor presentationanddiscussion of new or significant observations; and to foster research incancerandotherphenomenaof growth.―Membersof theAACRenjoythe followingbenefits:

1. subscriptions to the journals Cancer Research, CellGrowth& Differentiation,and CancerEpidemiology,Biomarkers& Preventionat the reducedmemberrate;

2. the privilegeof sponsoringan abstractfor presentationatthe AACRannualmeeting;

3. an advance copy of the Program and Proceedings pertaining to eachannualmeeting;

4. a reduced registration rate at all scientific meetings;5. early notification of events in the AACR's series of special

conferences;6. subscriptions to any future AACR journals at reduced

memberrates;7. reduced rates for the AACR Employment Register;8. the benefit of AACR's public education activities;9. the receipt ofAACR newsletters, meeting announcements,

and an up-to-date membership directory.

QUALIFICATIONSFOR MEMBERSHIP

Activemembershipin the AACRis opento investigatorswholive in the Americas, and who have conducted two years ofmeritoriousresearchthat hasresultedin publicationsrelevanttocancer. If a candidate is working in a research area not directlyrelatedto the cancerfieldbut hasconductedresearchof exceptionalscientificmerit,heor shemayalsoqualifyfor membership.

Correspondingmembershipis opento qualifiedpersonswhoare not residentsof the Americas.The requirementsfor correspondingmembershipare the sameas those for active membership.VisitingscientistsfromoutsidetheAmericaswhointendto return to their countriesof originsoon after submittingtheirapplicationsshould apply for correspondingmembership.Allotherindividualsshouldapplyforactivemembershipandtransferto correspondingstatus at a laterdate if they shouldleavetheAmericas.

PROCEDURESFOR APPLICATION

Thereare three deadlinesfor receiptof a membershipapplication: March 1, July 1, and October 1 of each year. TheMembershipCommitteewill reviewall completeapplicationsforactive membership that have been received by these deadlinesandwillsubmitrecommendationsoneachcandidateto theBoardof Directorswhich formallyelectsall members.The sameprocedure is followed by the Special Memberships Committee whichreceives applications for corresponding membership. Candidates

will be notifiedaccordingto the followingschedule:

Receipt of Applicationin AACROffice Notificationof Candidate

March1 MayJuly 1 SeptemberOctober1 December

A complete application consists of the following material:

1. 6 copiesof the form on the oppositeside of this page,with all requestedinformationprovided.

(City) (State/Province)TELEPHONENUMBER:FAXNUMBER:

PRIMARYFIELDOF RESEARCH(Pleasecheckonlyone):BiochemistryandBiophysics BiostatisticsCellularBiologyandGenetics ClinicalInvestigationsEpidemiology ImmunologyPreclinicalPharmacologyandExperimentalTherapeuticsVirology Other:(Country)

(PostalCode)

CarcinogenesisEndocrinologyMolecularBiologyandGenetics(Please

specify)ACADEMIC

DEGREES(Includingwhereandwhengranted)EXPERIENCE

SINCEHIGHESTDEGREEWASGRANTED(Pleaselist most recentfirst)

PUBLICATIONS(Reprintsof two articleson whichthe candidateappearsas anauthormustaccompanythis application.Forthesetwo articles list the authors, title, journal, volume, indusive pages, and year. Do not submit abstracts.)

CANDIDATENOMINATEDBY:____________________ CANDIDATESECONDEDBY:____________________(Pleasetypeor print) (Pleasetypeor print)

STATEMENTOFSUPPORT(inplaceof lettersof recommendation)Insteadof submittinglettersof recommendation,eitherthe nominatoror the seconderor bothmaycompletethe followingsection:

How long has the candidate worked in the field of cancer How long has the candidate worked in the field of cancerresearch?_ years research? yearsWill the candidate make a long-termcontribution to cancer Will the candidatemake a long-termcontribution to cancerresearch? Yes No research?___ Yes NoDoesthecandidate'sresearchadhereto acceptedethicalstand- Doesthecandidate'sresearchadhereto acceptedethicalstandards? __ Yes No aids? ___ Yes ___ No

I therefore recommendthis candidatefor membershipin the I therefore recommendthis candidatefor membershipin theAmerican Association for Cancer Research. American Association for Cancer Research.

Signatureof nominator― Date Signatureof seconders Date

SeeGuidelinesfor Applicationon the reversesideof this formfor furtherinstructions.

S Both nominator and seconder must be active, emeritus, or honorary members of the AACR.

(This form may be reproduced.)

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •620 Chestnut St. •Suite 816 •Philadelphia, PA 19106-3483

APPLICATIONFOR MEMBERSHIP

CATEGORYOF MEMBERSHIP: 0 Active 0 Corresponding

NAMEOFCANDIDATE:_____________________________________ DATEOFBIRTH:_______LAST FIRST M.I.

PRESENTPOSITION/TITLE:INSTITUTIONALAFFILIATION:INSTITUTIONALADDRESS:

QUALIFICATIONS FOR MEMBERSHIP

Associatemembershipis opento graduatestudents,medicalstudents,postdoctoralfellows,and physiciansin trainingwholivein the Americasandwho are followinga courseof studyorwhoareworkingin a researchprogramrelevantto cancer.

BENEFITS OF MEMBERSHIP

The AmericanAssociationfor Cancer Research(AACR),ascientific society consistingof laboratoryand clinical cancerresearchers,was founded in 1907 “tobring together activeinvestigators of the cancer problem for presentation and discussion of new or significant observations; and to foster research incancerandotherphenomenaof growth.―AssociatemembersoftheAACRenjoythe followingbenefits:

1. the privilegeof sponsoringan abstractfor presentationatthe AACRannualmeetingprovidedthat (a) the associatememberis the presenterof the abstractand (b)an activemember in good standing of the AACR also signs theabstractin supportof the work (Inthis instance,the activememberwhocosignsthe abstractdoesnot losehisor herown sponsorshipprivilege.);

2. an advance copy of the Program and (if one has beenpurchased by the associate member) the Proceedings ofthe American Association for Cancer Research which containsabstractsof allpapersbeingpresentedateachannualmeeting;

3. the privilege of registering for the annual meeting at thelow student rate (This rate is otherwise available only topredoctoralstudents.);

4. preferred access to the AACR Employment Register;5. optional subscriptionsto the journals CancerResearch,

Cell Growth & Differentiation, and Cancer Epidemiology,Biomarkers & Prevention at the reduced member rate;

6. subscriptions to any future AACR journals at reducedmember rates;

7. early notification of events in the AACR's new series ofsmallscientificmeetingson timelyscientifictopics;

8. the receipt of AACR newsletters, meeting announcements,and an up-to-date membership directory; and

9. thefacilitationof informalscientificexchangewithleadingresearchersin the cancerfield.

PROCEDURES FOR APPLICATION

Persons wishing to apply for associate membership must usethe officialapplicationform on the reversesideof theseinstructions.Eachcandidatefor associatemembershipmust be nominated by an active member in good standing of the AACR. Threecompleted copies of the form should be submitted; at least oneof these copies must carry the original signatures of both thecandidate and the active member nominator. The applicationform may be submitted to the Association Office at any time.

After reviewof applicationsfor associatemembership,the ExecutiveDirectorwill notifycandidatesof theirelectionor deferralwithin one month of the receipt of the application form. A checkintheamountof $20,whichrepresentsoneyear'sduespayment,must accompanythe application.This fee will be refundedtoanycandidatedeemedto beineligiblefor associatemembership.Checksshouldbe in U.S.currency,madepayableto AACR,Inc.,anddrawnon a U.S.bank.Sendthe threecopiesof the application form and the $20 dues payment to:

AmericanAssociationfor CancerResearchPublic Ledger Building

620 Chestnut St.Suite816

Philadelphia,PA I 9106-3483215/440-9300

RESPONSIBILITIES OF MEMBERSHIP

Associatemembersmustpayannualduesin anamountto bedeterminedby theAACRBoardof Directors.Duesfor 1992havebeen set at $20 per year. If an application is submitted by August31, the accompanyingdues paymentwill be credited to thecurrentyear.CandidatessubmittingapplicationsbetweenSeptember1 andDecember31 mayindicatewhethertheywishtheirdues paymentscredited to the current or forthcomingyear.Candidatesshouldbeaware,however,that associatemembersmay sponsor an abstract for the annual meeting only if their duesfor thecurrentyeararepaid.Forexample,anassociatemembersubmittingan abstract in December1991 for the forthcomingannualmeetingmusthavepaidduesfor 1991.Anynewlyelectedassociate members of the AACR who have already purchasedsubscriptions to Cancer Research, Cell Growth & Differentiation,or CancerEpidemiology,Biomarkers& Preventionat the higher,nonmemberratewill receivea refundfor the unusedportionofthat subscriptionuponreceiptof their paymentfor a member'ssubscription.

EachFall the AACRwill sendto currentassociatemembersan invoicefor dues for the forthcomingyear. Paymentof thisinvoicemust be accompaniedby a statementsigned by theassociatemember'scurrentregistrar,dean,or departmenthead,verifyingthe member'scurrentacademicstatus. The Association's By-Laws state that dues are payablefor each year inadvanceonor beforeJanuary1of theyearto whichtheyshouldbe applied.An individualmay be an associatememberfor amaximumof five years.Eachyear in which an individualpaysdueswill countas onefull yearof associatemembership.Thus,an associate member who pays dues for 1991 may retainassociatemembershipuntil December31, 1995. The BoardofDirectorsmayterminatethemembershipof anassociatememberwhoseduesare in arrearsfor two years.

MargaretFoti,ExecutiveDirector

,±@? AMERICANASSOCIATIONFORCANCERRESEARCH@ ‘/

@@@ I@@ GUIDELINES FOR APPLICATION FOR ASSOCIATE MEMBERSHIP

@ ‘@@a@‘

NAMEOFCANDIDATE:APPLICATIONFORASSOCIATEMEMBERSHIP

IDATE

OFBIRTH:________________LASTFIRSTM.I.INSTITUTIONAL

AFFILIATION:INSTITUTIONALADDRESS:

(City) (State/Province) (PostalCode) (Country)TELEPHONENUMBER:_____________________FAX NUMBER: ___________________________

PRESENTACADEMICSTATUS/TITLE(Pleasecheckonlyone):____GraduateStudent ____MediCalStudentPhysician in Training Postdoctoral Fellow

PRIMARYFIELDOF RESEARCH(Pleasecheckonlyone):BiochemistryandBiophysics Biostatistics Carcinogenesis

_____CellularBiologyandGenetics _____ClinicalInvestigations EndocrinologyEpidemiology Immunology MolecularBiologyandGenetics

____PreclinicalPharmacologyandExperimentalTherapeuticsVirology Other:

(F@easespecify)

ACADEMICDEGREES(Pleaseindicatedegree(s)acquiredto date alongwith the nameof the academicinstitutionand date ofreceipt.Provideinformationon degreecurrentlybeingsoughtandthe anticipateddateof completionof this degreeprogram.)

RELEVANTRESEARCHEXPERIENCENOTRELATEDTO COURSEWORK(Pleaselist mostrecentfirst.)

PUBLICATIONS (Ust the authors, title, journal, volume, inclusive pages, and year of any article in a peer-reviewed journal on whichthe candidateappearsas an author.Donot list abstracts.Continueon a separatesheet,if necessary.)

CANDIDATE NOMINATED BY:(Please type or print name of AACR active member in good standing.)

SIGNATURESI herebyapply for associatemembershipin the AmericanAssociationfor CancerResearch.I haveread the instructionson thereverse side of this form, and I understand the privileges and responsibilities of this class of membership. I certify that the statementson this applicationaretrue.Signatureof Candidate:_______________________________________________________Date:___________________

I recommendthis candidatefor associatemembershipin the AmericanAssociationfor Cancer Research.To the best of myknowledge,the candidateis qualifiedfor this classof membership,andthe statementson this applicationaretrue.Signatureof Nominator―:______________________________________________________ ___________________Submit three copies of this form. At least one copy must contain the original signatures of the candidate and the nominator. Enclosea check for $20 in U.S. funds made payable to AACR, Inc. and drawn on a U.S. bank. Check one of the following boxes only if thisform is being submitted between September 1 and December 31:

Theenclosedduespaymentshouldbe appliedto the0 current 0 forthcoming calendar year.

(NOTE:If duesareappliedto the forthcomingyear,membershipwill take effecton January1, but the candidatewill not be eligibleto sponsoran abstractfor presentationat the annualmeetingin Mayof that year.)SeeGuidelinesfor Applicationon the reversesideof this formfor furtherinstructions.

C Nominator must be active, emeritus, or honorary member of the AACR.

(Thisformmaybereproduced.)

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •620 Chestnut St. •Suite 816 •Philadelphia, PA 19106-3483

PLEASEFILL OUT ALL INFORMATIONON REVERSESIDE AND SUBMITTHIS FORMWITH YOUR DISK.DISKSWILL NOTBE PROCESSEDWITHOUTTHISINFORMATION.

toAmericanAssociationfor CancerResearchPublications

The word processing packages that we prefer are as follows:

XyWnte III Plus (for the IBM)WordPerfect 4.2, 5.0, 5.1 (for the IBM)WordPerfect (for the Mac)Wordstar (for the IBM)

Also acceptable:

Apple II DOS 3.3Apple with Appleworks SoftwareApple Ill Plus DOS 3.3Apple MacIntosh 400K Disc!

MacWrite 2.2 (text)Apple MacIntosh Plus 800K Disc/

MacWrite 4.5 (text)CPT 8000DEC WPS-8DEC DecmateIIDEC DecmateIllDisplay Write 3

Microsoft Word (for the IBM)Microsoft Word MacIntosh

(Versions 1—4)400/800KWang 015 (WPS)

Display Write 4IBM Displaywriter Word Processor 6580Lanier Business One StepLanier No ProblemLanier Super No ProblemMASS-il PCMultimatePC WritePFS Professional WriteVolkswnter 4.0

Newreleasesof word processingsoftwareare not alwaysimmediatelyavailablefor conversion.In addition,becauseof the file structuresand internalcoding,we cannot accept disks createdon desktop publishingsystems or those created on proprietary typesetting systems. We also cannot guarantee that all specialcharacterscanbetranslated.Tabularandmathematicalmaterial,suchasequations,willnot becapturedfromthe disk but will be rekeyed.

To expeditework andfor your own security,we do requirethat you submita hardcopy printoutof the diskfile. The tables and equations will be keyed from this hard copy. We also need to know the name of the file tobeconverted,the typeof hardware(e.g., IBMPC)on whichthefileswerecreated,theoperatingsystem(e.g.,DOS3.3),andthe versionof the software(e.g., WordPerfect5.1)usedto createthe file.

Guidelines for Submitting Disks

@@1

DISK SUBMISSION FORM

AACRjournalsarenowusingpersonalcomputerstocopyeditmanuscriptsacceptedforpublication.Whensubmittinga revisedmanuscript,authorsareencouragedto submitanelectronicdisk of the paperalongwiththe requiredfour hardcopy printouts.Diskswill ultimatelybe returnedto the authors.

I Seereverseforthewordprocessingpackagesthatcanbeaccepted.File preparation

Pleasebe sure that the file you send is the most recentversionof the manuscriptand that it matchesthemost recently submitted printed copy. The file should contain all the parts of the manuscript in one file.Mathematicalandtabularmaterial,however,will beprocessedin the traditionalmannerandmaybeexcludedfromthe disk file.

Note:AACRdoesnot assumeresponsibilityfor errors in conversionof customizedsoftware,newlyreleasedsoftware,or specialcharacters.

Pleaselabel the outside of the disk with the journal name, the first author's name,a partial title of themanuscript, and the name of the computer file used to access the manuscript on disk. To process your diskefficiently,we needthe followinginformation.Pleasebesureto provideALL the information.

Name usedtoaccesspaperondisk:____________________Nameof computerused(e.g.,IBM/PS2):Operating system and version (e.g., DOS 3.3):Wordprocessingprogramandversion(e.g.,WordPerfect5.0):

[See reverse for acceptable prograrns.1

Manuscript number: __________________________________First author: __________________________________________

Corresponding author (if different from first author):Telephone/FAX numbers: ____________________________

This form (both sides) may be reproduced.

AACR SPECIAL CONFERENCEIN CANCER RESEARCH

OncogenesandAntioncogenesin Differentiation,Development,andHumanCancer

February1-6, 1993Big Sky Resort,Big Sky, Montana

CONFERENCE CHAIRPERSON

Carlo M. Croce I Philadelphia, PA

PROGRAM COMMITTEE

Stuart A. Aaronson I Bethesda,MDMarioR.CapecchiI SaltLakeCity,UT

Douglas Hanahan I San Francisco, CA

SCIENTIFIC PROGRAM

TumorSuppressorGenesEricJ.StanbridgeI Irvine,CAWen-HuaLeeI SanAntonio,TXDavidE.HousmanI Cambndge,MALennartPhillpsonI Heidelberg,GermanyKarenVousdenI London,England

Expressionof ActivatedOncogenesinTransgenicMiceIAllanBalmainI Glasgow,ScotlandRObertS.coffey I Nashville,TNGilbert Jay I Rockville, MDGeorgeF.VandeWoudeI Frederick,MD

Expressionof ActivatedOncogenesinTransgenicMiceIITerryVanDykeI Pittsburgh,PAAntonBarnsI Amsterdam,TheNetherlandsAdditionalSpeakerto beAnnounced

KeynoteAddressRaymondL WhiteI SaltLakeCity,UT

GeneKnockoutsby HomologousRecombinationIMarioR.CapecchiI SaltLakeCity,UTAllanBradleyI Houston,TXTyler Jacks I Cambridge, MABruce N. Spelgelman I Boston,MA

GeneKnockoutsby HomologousRecombinationIIErwin Wagner I Vienna,AustriaHaroldE.VarmusI SanFrancisco,CADouglasHanahanI SanFrancisco,CA

SignalTransductionandCancerIStuartA.AaronsonI Bethesda,MDLewisC.CantleyI Boston,MAJohnJ.CohenI Denver,CODavidV.GoeddelI S.SanFrancisco,CA

SignalTransductionandCancerIIMichaelH.WiglerI ColdSpringHarbor,NYEdwardB.ZIttI NewYork,NYMichaelJ.Weber/Richmond,VA

ChromosomalTranslocationsandCancercarloM.CroceI Philadelphia,PAMichaelL ClearyI Stanford,CAEliCanaaniI Philadelphia,PAAnneDejeanI Pans,France

Application Deadline: December 7, 1992

Information and Application Forms

American Association for Cancer ResearchPublic Ledger Building620 ChestnutStreet,Suite816Philadelphia, PA 19106-3483215-440-9300 215-440-9313 (FAX)

60-Day Release Estmgen Pellets and lämoxifen PelletsFor Thmor Growth andRegression

rvl@ scientistsagreethatthegrowthorregression of estrogen-dependent tumor tissue

in nude mice depend on three factors:

. The tumor tissue itself

. A healthy and untraumatized nude mouse

. Exogenous estrogen or anti-estrogenready-to-implant pellets from Innovative

Research

\X@Teofferresearcherstheproven60-dayreleaseimplantable/ removable 17f3-Estradiolpellets andTamoxifen pellets.

Aithoughourcatalogoffersawiderangeofdosages and release times for these prOdUCtS, the

most commonly used in nude mice studies are:

PRODUCT MG/PELLET CAT NO. DIAMETER RELEASE TIME BLOOD LEVELS

17f3-ESTRADIOL 0.72 SE-121 3 mm 60-day 200—400 pg/mi

17f3-ESTRADIOL 1.7 SE-121 3 mm 60-day >900 pg/mi

TAMOXIFEN 5 SE-361 3 mm 60-day 3—4ng/ml

Thesepelletsaredesignedforsimplesubcutaneous implantation in nude mice with a 10

gauge precision trochar (Cat. No. MP-182).

0 order these products, please call, write,or fax or you may also request our catalogwhich lists several thousand ready-to-implant

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Innovative Research

of America TELEPHONE TELEFAX3361 Executive Parkway USA/Canada 1-800-421-8171 USA/Canada 1-800-648-6030P.O. Box 2746Toledo, Ohio 43606, USA All Others 419-531-0066 All Others 419-531-4422