Welcome to the unique world of Chemelot Campus

November 14th 2012 Frank Schaap

What is Chemelot?

One of the largest chematerial communities in Europe (> 800 ha)Industrial Park + CampusNumber of companies on site > 100; 70 new companies since 2005Many of them global leaders in their product market combination6.000 jobs on Chemelot; approx 1.500 visitors per day

Industrial ParkSharing infrastructure and

costs

CampusSharing knowledge and

global networks

Chemelot, many global leaders

What is Chemelot?

Maastricht

Ein

dhov

enBru

ssel

s

Aachen

Chemelot CampusThree shareholders: triple helix

Dutch Province of Limburg

DSM Nederland

Maastricht University/Maastricht UMC+

Common goal:Growth of regional economy by accelerated growth of Chemelot Campus

Chemelot ambition

A globally recognized chematerials valleyoffering

accelerated business growth for all parties involved

1 + 1 > 3 !

Unique strengths

Performance Materials

Advanced (bio) organic

chemistry

Process technology

Analytical support

Unique strengths

Performance Materials

Advanced (bio) organic

chemistry

Process technology

Analytical support

BioMedical Materials

BioBased Materials

Micro reactor technology

Chemelot Campus focus sectors

Performance Materials

Biobased Chemicals and Materials

Biomedical Materials

Biosynthesis

R&D Enabling Technologies

70 new members of Chemelot Community (since 2005)

Start up’s

Small Medium Enterprises (SME’s)

Multinationals: Manufacturing and/or R&D

Knowledge Institutes (Universities, Technical High Schools)

Public Private Partnership programs

Service providers

Chemelot Campus developmentbase case scenario 2011 - 2020

0

500

1000

1500

2000

2500

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

2020

Onderwijs en kennisinstellingen

Nieuwe Campus bewoners vanaf2011Bestaande Campus bewoners(niet DSM)DSM spin off's en divestments

Service boulevard

DSM R&D

Change in time 2012 to 2020

Real Estate Developments, example 1

DSM Materials Science CenterCompletion Date: 01-07-2014

Labs and offices

R&D and Sales offices

420 FTE

Developments14

Real Estate Developments, example 2

Lanxess headquarter buildingCompletion Date: 31-12-2012

Labs and offices

R&D and Sales offices

120 FTE (ca. 25 from Leverkusen)

Lanxess HTE installationCompletion Date: 01-07-2013

Labs and offices in 6.0

12 FTE

Developments15

Value Creation by Open Innovation1

Fuz

zy F

ront

End

1c. Interaction / Synthesis

8 Intellectual Asset Management

4aLicensing

In 5Venturing 6a

Spin in

2 Joint

Business Developments

7aAcquisitions

4bLicensing

Out

6bSpin out

7bDivestments

3R&D services

1a Market Scouting / Business Intelligence

1b Competence Development, Technology Intelligence

Open innovation is no longer a competitive advantageIt has become a competitive necessity!

Open innovation at Chemelot

Start up

SME

Open innovation at Chemelot

Start up

SME

EXAMPLES1 + 1 > 3 !

Unique strengths

Performance Materials

Advanced (bio) organic

chemistry

Process technology

Analytical support

BioBased Materials

Innovation happens naturally,ask Avantium......

Avantium

• Technology company (IP)• Spin-off from Royal Dutch Shell in 2000• Proven expertise in catalysis research & technology• Development of biobased materials and fuels• 130 employees• Based in Amsterdam, expanding to Chemelot• Listed in the Guardian Cleantech Top 100• World player

Avantium customer base:

BioMaterial products

BioBased Chemicals and Fuels

BioPolymers

Fermentation

PolymerizationFermentation

Compounding Formulation

BioBased materials valuechain

Carbon Source& other renew.

Fermentation/Chemical conversion

Unique combination of biotech and materials market know-how

Pilot plant goals

1. Product for application development

2. Optimal process conditions

3. Select the best catalysts

4. Select equipment

5. Scale up data

6. Durability

Strategic Joint Development Partnerships

Why did Avantium select Chemelot?

Strong fit with chemistry, processing and new materials community

Access to unique existing infrastructure

Availability of service and support providers

Human capital (operators, engineers, specialists)

Possibility to go to larger scale and commercial production

Unique strengths

Performance Materials

Advanced (bio) organic

chemistry

Process technology

Analytical support

BioMedical Materials

DSM Biomedical - open innovation approach

Internal developmentChemelot Campus

VenturingExternal LicensingMergers & Acquisitions

Scientific Advisory Board BioMedical Materials Program

Professor Tony Mikos (Rice University, Houston, USA) Dr. Ivo Buschmann (Charité, University of Medicine, Berlin and Freiburg University, Germany), Mr. Patrick Cahalan, BSc (Ension Inc., Pittsburgh, USA)

Coatings and

Implants

Polymer enabled drug

delivery

Regenerative Medicine

Strategic pathway DSM Biomedical

Coatings and

Implants

Polymer-enabled drug

delivery

MagnaMedics

Coatings and

Implants

Innovation happens naturally, ask TiGenix

TiGenix, Why Chemelot?

Biomedical materials and regenerative medicine activities and business development focus (DSM Biomedical, Magnamedics, Interface BIOmaterials, Cellmade, Bio Medical Materials Program ….)Triple helix focus on regenerative medicine (regional governments, knowledge institutes and companies)Tailor made training program for cleanroom operatorsCentral location in Western EuropeLogisticsEnvironmental permitAvailability of fit for use space and infrastructureChemelot’s communityAdequate financing of € 5,4 mln for GMP cel expansion manufacturing facility (LIOF, Limburg Ventures, Particon, LRM)

Open innovation = collaboration between people

Open innovation = people working together

34

Goals and RolesChemelot Campus organization

Growth by “hunting”Attract new tenants

Generate new tenants (valorization)

Attract investments of existing tenants

Growth by “farming”Community building – connecting people

Cluster development

Service boulevard (real estate, business, R&D and general services)

Place to be for talented students and employees

Chemelot Campus community diversity potential

Material Sciences and Life Sciences

Global business leaders and Knowledge Institutes

Global networks and Regional networks

Professional corporate culture and entrepreneurial start up culture

Business mindset and students

Academic, HBO and MBO students and teachers

Triple helix representatives

Challenge: How to maximize synergy by social innovation?

Unlocking present unique know-how at Chemelot Campus is KSF

37

Bioscience Leiden

MHC

Accessible unique know-how

TwenteOss

Zwolle

CCHTC

GCC

Aachen Science

Park

Business Mindset

Strategic Groups in Campus arena• Industry nucleus creates business mindset• Academic nuclues creates accessibility of

knowledge• By introducing academic context at Chemelot

Campus, we introduce sharing culture being critical element for Open Innovation Ecosystem.

Chemelot Campus

Campus with same focus area

NL top Campusses

Expected move

WUR

A’damScience

Park

Techno-polis Delft

Chemelot

Chemelot, one of the most innovative chematerials communities in Europe

Chemelot designed to accelerate business growth through sharing of know-how, infrastructure and networks

Chemelot creates added value for the companies involved, their customers and suppliers and the region

Chemelot, a community of winners!

ChemelotInterested to relocate your business?

www.chemelot.com

Frank Schaap

Director Marketing & Business Development

+31-6-20 44 67 62

frank.schaap@dsm.com