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Viral DiseasesViral Diseases
Clinical classificationClinical classification
Vesicle form : vesicles dominated,such as Herpes Simplex ,Herpes Zoster and Varicella. Erythema form : Erythema dominated , such as Measles 、 Rubella and Erythema Infectioum. Neoplasm form : Verruca vulgaris,Verruca planae and Molluscum Contagiosum. STD form : Lymphogranuloma venereum.
Herpes simplexHerpes simplex
VericellaVericella
Herpes zosterHerpes zoster
Verruca vulgarisVerruca vulgaris
Verruca Verruca planaplana
Herpes zosterHerpes zoster
Zoster is a kind of acute skin infection caused by the varicella-zoster virus.
Manifestation: unilaterlly ; within the distribution of sensory nerve; little blisters in population; with neuralgia and lymphadenectasis; less recurrence after recovery
Etiology and MechanismEtiology and Mechanism
varicella-zoster virus.
humanhuman
varicellavaricella
Latent infLatent infectionection
Virus in the ganglia of cranial or spinal sensory nerve
InduInducing fcing factoractorss
Herpes zoHerpes zosterster
infectinfect
Clinical manifestationClinical manifestationPredilection human beings : adult
Early symptoms : moderate fever,malaise,local lymp
hadenectasis and neuralgia. Eruption characteristic : ( 1 ) erythema papule blister
( 2 ) distribute unilaterally in band within peripheral nerve ( 3 ) blisters in population ( 4 ) neuralgia and local lymphadenectasisPredilection sites : chest,waist,neck and the distribut
ion regions of trigeminal nerve.
course : 2 - 4 weeks
Special form Zoster (Special form Zoster (Ⅰ)Ⅰ)
Herpes zoster without eruptionsAbortive type Herpes Zoster Bullous,hemorrhagic or necrotic Herpes ZosterDisseminated Herpes Zoster
Herpes ZosterHerpes Zoster (( hemorrhagihemorrhagi
c)c) ))
Special Herpes ZosterSpecial Herpes Zoster ((ⅡⅡ))
virus Motor neurons virus Motor neurons MyastheniaMyasthenia ,, skin paralysisskin paralysisvirus geniculate ganglion(involvment of thevirus geniculate ganglion(involvment of the facial and auditory nerves)facial and auditory nerves) RamseyRamsey -- Hunt syndrome Hunt syndrome : : Zoster of the external ear, ear pain, Zoster of the external ear, ear pain, facial paralysis, vertigo. facial paralysis, vertigo.
DiagnosisDiagnosis
Lesions:erythema,papule and blisters; Blisters in population; distribute unilaterally in band within peripheral nerve; with neuralgia.
Treatment principlesTreatment principles The prevention of neuralgiaantivirus : ACV 0.2 q4h X 5 - 10d Valaciclovir 0.3bid X 5 - 10dantiinflammationTopical treatmentPrevent secondary infection
Molluscum contagiosa Molluscum contagiosa
papule dermatosis,caused by MCV characteristics: smooth surfaced and dome shaped
pearly papules; central umbilication; molluscum body.
Etiology and MechanismEtiology and Mechanism
Molluscum Contaguosum Virus transmitted by direct skin to skin contact; or auto-inoculation
Clinical manifestationClinical manifestation
Predilection human beingsPredilection human beings :: children and youtchildren and youth. Latent time: 2-3 weeks.h. Latent time: 2-3 weeks.
FeatureFeature of lesionsof lesions :: 3 to 5mm in diameter3 to 5mm in diameter semisphere-like , pearly papulessemisphere-like , pearly papules central umbilicationcentral umbilication squeeze out white cheese-like substancesqueeze out white cheese-like substance number: several to many number: several to many no confluenceno confluence
Clinical manifestationClinical manifestationPredilection sitesPredilection sites :: trunk, extremities,scrotum and eyelidtrunk, extremities,scrotum and eyelid sometimes lip, tone and sometimes lip, tone and buccal mucosa are involved. buccal mucosa are involved.
coursecourse :: 66 -- 9months9months ,, individually:4individually:4 -- 5years or longer.5years or longer.Symptoms: NO or moderate itching.Symptoms: NO or moderate itching.
TreatmentTreatmentIsolationNicking with trichloracetic ac
id(33 % ) 10 % potassium hydroxide
Definition scabies is one kind of parasitosis caused by Sarcoptes scabies which invade th
e skin of the finger webs,antecubital fossae, the lower abdomen,genitals and scrotum ect, and characterized by pruritic papular, bullous lesions and also burrows.
transimitted by skin to skin contact
ScabiesScabies
Etiology Etiology
Life of Life of Sarcoptes scabies
adultadult femalefemale
malemale
matingmatingFemale ovulateFemale ovulate
Male diedMale diedovumovum
3-4 da3-4 daysys
larvalarva nymphaenymphae adultadultTwice ecdysisTwice ecdysis
2-3 day2-3 dayss
7-14days 7-14days
Infection styleInfection style :: mostly direct skin to skin contactmostly direct skin to skin contact,,
a few infected by indirect contacta few infected by indirect contact
Clinical manifestationClinical manifestation ::Predilection human beings : anyone Feature of eruption : 1 papulovesicles with no confluence 2 burrows 3 scabies nodule Predilection sites: the finger web,medial wrist, antecubital fossae,areas around the waist, the lo
wer abdomen, genitals and groins ect.Intense itch: especially in night
The finger webThe finger web
DiagnosisDiagnosis eruption : burrows papulovesicles and blisters scrotum nodulespredilection sites: especially the finger
web and external genitals. intense itch: especially in night infect collectively:the same patients in
one family. most convinced evidence: Sarcoptes sc
abies or its eggs.
Differential diagnosisDifferential diagnosis
PruritusPapular urticariaPediculosis
TreatmentTreatment
10% Oint. Sulfur10% Oint. Sulfur
Solution of killing Solution of killing Sarcoptes scabies
Cream. 10Cream. 10 % % CrotamitonCrotamiton