VALENCIA. 13th -14th DECEMBER 2018 · 2018. 11. 23. · VALENCIA CONFERENCE CENTRE 26 VALENCIA. 13th -14th DECEMBER 2018 SCIENTIFIC PROGRAM ADVANCES IN THE TREATMENT OF DIGESTIVE

VALENCIA CONFERENCE CENTRE

26 VALENCIA. 13th -14th DECEMBER 2018

SCIENTIFIC PROGRAMADVANCES IN THE TREATMENT OF DIGESTIVE TUMOURS

Organized by

Under the auspices of

Scientific and sanitaryinterest accredited by

INTERNATIONALSYMPOSIUM

SPANISH COOPERATIVE GROUP FOR DIGESTIVE TUMOUR THERAPY

Acredited by

Health Professions Continuous Formation Commission fo the Community of Valencia

26 INTERNATIONALSYMPOSIUM

2

Dear friend,

On behalf of the Digestive Tumour Treatment Group (TTD), we are pleased to invite you to the 26th International Symposium of our group, which this year is being held in Valencia on 13 and 14 December.

Year after year, this event has continued to establish itself as a meeting point and reference for all those oncologists and other specialists involved in the research and treatment of digestive tumours. As in previous years, the event will welcome leading professionals from Spain and abroad to review and reach a consensus on the advances in patient care.

The programme comprises two tables dedicated to localised colorectal cancer. On the first, we will analyse the possibility of minimising adjuvant treatment and its associated toxicity in colon cancer, while on the rectal cancer table, we will focus on evaluating the response and suitability of subsequent treatment. In addition, the latest advances in hepatobiliary, pancreatic and neuroendocrine tumours will be reviewed from a multidisciplinary perspective. There will also be a keynote speech on the clonal evolution of colon cancer. On the second day, we will address the comprehensive management of gastro-oesophageal tumours and will finish with a review of the treatment of metastatic colorectal cancer, with special emphasis on treatment selection, targeted therapies and the incipient role of immunotherapy.

We hope that you find the programme interesting and enjoyable. It will be an honour for us to welcome you to Valencia and benefit from your active participation, which will undoubtedly contribute to increasing the educational value of the symposium.

Mª José SafontAndrés Cervantes

INTRODUCTION

ADVANCES IN THE TREATMENTOF DIGESTIVE TUMOURS

3

ORGANIZING COMMITTEE: COORDINATOR

ORGANIZATION

Mª José SafontHospital General UniversitarioValencia, Spain

Andrés CervantesHospital Clínico UniversitarioValencia, Spain

ORGANIZING COMMITTEE: VOCALSEnrique Aranda Hospital Universitario Reina SofíaCórdoba, Spain

Manuel BenavidesHospital Regional Universitario y Virgen de la VictoriaMálaga, Spain

Alfredo CarratoHospital Universitario Ramón y CajalMadrid, Spain

Eduardo Díaz-RubioHospital Universitario Clínico San CarlosMadrid, Spain

Ana Fernández MontesComplejo Hospitalario UniversitarioOrense, Spain

Pilar García Alfonso Hospital Universitario Gregorio MarañónMadrid, Spain

Begoña GrañaComplejo Hospitalario UniversitarioLa Coruña, Spain

Cristina GrávalosHospital Universitario 12 de OctubreMadrid, Spain

Jerónimo Jiménez CastroHospital Virgen del RocíoSevilla, Spain

Paula Jiménez FonsecaHospital Universitario Central de AsturiasOviedo, Spain

Carles PericayCorporación Sanitaria Parc TaulíSabadell, Spain

Fernando RiveraHospital Universitario Marqués de ValdecillaSantander, Spain

Ramón SalazarICO. Hospital Duran i ReynalsBarcelona, Spain

Javier SastreHospital Universitario Clínico San CarlosMadrid, Spain

Josep TaberneroHospital Universitari Vall d´HebrónBarcelona, Spain


FACULTY

Antón, AntonioHospital Universitario Miguel ServetZaragoza, Spain

Aranda, EnriqueHospital Universitario Reina SofíaCórdoba, Spain

Arnold, DirkInstituto CUF de OncologiaLisbon, Portugal

Bass, AdamDana-Farber Cancer InstituteBoston, United States

Beets, Geerard Netherlands Cancer InstituteAmsterdam, The Netherlands

Benavides, ManuelHospital Regional Universitario y Virgen de la VictoriaMálaga, Spain

Blomqvist, LennartKarolinska InstitutetStockholm, Sweden

Buyse, MarcInternational Drug Development InstituteSan Francisco, United States

Carrato, AlfredoHospital Universitario Ramón y CajalMadrid, Spain

Cervantes, AndrésHospital Clínico UniversitarioValencia, Spain

Díaz-Rubio, EduardoHospital Universitario Clínico San CarlosMadrid, Spain

Fernández Montes, AnaComplejo Hospitalario Universitario Orense, Spain

García Alfonso, Pilar Hospital Universitario Gregorio MarañónMadrid, Spain

García Carbonero, RocíoHospital Universitario 12 de OctubreMadrid, Spain

Glynne-Jones, RobMount Vernon HospitalNorthwood, United Kingdom

Gómez España, AuxiliadoraHospital Universitario Reina SofíaCórdoba, Spain

González Flores, EncarnaciónHospital Virgen de las NievesGranada, Spain

Graña, BegoñaComplejo Hospitalario UniversitarioLa Coruña, Spain

Grávalos, CristinaHospital Universitario 12 de OctubreMadrid, Spain

Grothey, AxelWest Cancer Center, University of TennesseeGermantown, United States

4


Jiménez Fonseca, PaulaHospital Central de Asturias Oviedo, Spain

Lamarca, ÁngelaThe Christie NHS Foundation Trust (ENETS Centre of Excellence) Manchester, United Kingdom

Macarulla, TeresaHospital Universitari Vall d´HebrónBarcelona, Spain

Massutí, BartomeuHospital General Universitario Alicante, Spain

Pericay, CarlesHospital de Sabadell. Corporación Sanitaria Parc TauliSabadell, Spain

Rivera, FernandoHospital Universitario Marqués de ValdecillaSantander, Spain

Sabater, LuisHospital Clínico Universitario Valencia, Spain

Safont, Mª JoséHospital General UniversitarioValencia, Spain

Salazar, RamónICO. Hospital Duran i ReynalsBarcelona, Spain

Sastre, JavierHospital Universitario Clínico San CarlosMadrid, Spain

Seymour, MatthewLeeds Institute of Cancer and Pathology, University of LeedsLeeds, United Kingdom

Siravegna, GiuliaCandiolo Cancer Institute-FPO, IRCCS Candiolo, Italy

Smyth, ElizabethCambridge University Hospitals NHS Foundation Trust,Cambridge, United Kingdom

Valladares, ManuelHospital Universitario Reina SofíaCórdoba, Spain

Van Cutsem, EricGasthusberg University HospitalLeuven, Belgium

Vera, Ruth Complejo Hospitalario de NavarraPamplona, Spain

Viéitez, José Mª MD Anderson Cancer CenterMadrid, Spain

5


SCIENTIFIC PROGRAM

09:00-10:00 SATELLITE SYMPOSIUM. Sponsored by Sanofi.

10:15-10:30 INAUGURATION

1ª TABLE. LOCALIZED COLON CANCER

Moderators: A. Antón (Hospital Universitario Miguel Servet, Zaragoza. Spain). C. Pericay (Hospital de Sabadell. Corporación Sanitaria Parc Tauli, Sabadell. Spain).

10:30-10:45 Current value of adjuvant treatment in stage III colon cancer. A. Cervantes (Hospital Clínico Universitario de Valencia, Valencia. Spain).

10:45-11:05 Statistical evaluation of the IDEA study. M. Buyse (International Drug Development Institute, San Francisco. United States).

11:05-11:25 Clinical evaluation of the IDEA study. A. Grothey (West Cancer Center, University of Tennessee Germantown. United States).

11:25-11:45 Could neoadjuvant therapy become a standard treatment in colon cancer? M. Seymour (Leeds Institute of Cancer and Pathology, University of Leeds, Leeds. United Kingdom).

11:45-12:15 Discussion.

12:15-12:45 Coffee-break.

THURSDAY, 13 DECEMBER

19:00-21:00 SATELLITE SYMPOSIUM. Sponsored by Amgen.

WEDNESDAY, 12 DECEMBER

6


2ª TABLE. CHALLENGES IN RECTAL CANCER

Moderators: A. Gómez España (Hospital Universitario Reina Sofía, Córdoba. Spain) Mª J. Safont (Hospital General Universitario, Valencia. Spain)

12:45-13:05 Multiparametric imaging for assessment of response to neoadjuvant treatment in rectal cancer. L. Blomqvist (Karolinska Institutet, Stockholm. Sweden).

13:05-13:25 Patient selection for conservative treatment in rectal cancer. G. L. Beets (Netherlands Cancer Institute, Amsterdam. The Netherlands).

13:25-13:45 Should we use short-course radiotherapy more in rectal cancer? R. Glynne-Jones (Mount Vernon Hospital, Northwood. United Kingdom).


14:150-14:30 RESOLUTION OF CASE STUDY CONTEST

14:30-16:00 LUNCH

3ª TABLE. MULTIDISCIPLINARY APPROACH TO PANCREAS CANCER

Moderators: A. Carrato (Hospital Universitario Ramón y Cajal, Madrid. Spain). R. Vera (Complejo Hospitalario de Navarra, Pamplona. Spain).

16:00-16:20 Pancreatic borderline cancer. Definition and treatment. L. Sabater (Hospital Clínico Universitario de Valencia, Valencia. Spain).

16:20-16:40 The role of neoadjuvant chemotherapy in locally advanced pancreatic cancer. A. Fernández Montes (Complejo Hospitalario Universitario de Ourense. Spain).

16:40-17:00 Towards an optimal treatment sequence in metastatic pancreatic cancer. B. Graña (Complejo Hospitalario Universitario, La Coruña. Spain).

7


SCIENTIFIC PROGRAM

17:00-17:20 Experimental treatments in pancreatic cancer. T. Macarulla (Hospital Universitario Vall d’Hebrón, Barcelona. Spain).



KEYNOTE ADDRESS

Moderator: E. Díaz-Rubio (Hospital Universitario Clínico San Carlos, Madrid. Spain).

18:20-18:50 Evaluating clonal evolution in colon cancer. G. Siravegna (Candiolo Cancer Institute-FPO, IRCCS; University of Torino, Candiolo. Italy).

4ª TABLE. UPDATES ON THE TREATMENT OF OTHER DIGESTIVE NEOPLASMS

Moderators: J. Mª Viéitez (MD Anderson Cancer Center, Madrid. Spain). C. Grávalos (Hospital Universitario 12 de Octubre, Madrid. Spain).

18:50-19:10 Cholangiocarcinoma. Á. Lamarca (The Christie NHS Foundation Trust (ENETS Centre of Excellence), Manchester. United Kingdom).

19:10-19:30 Neuroendocrine tumors. R. García Carbonero (Hospital Universitario 12 de Octubre, Madrid. Spain).

19:30-19:50 Update on the treatment of hepatocarcinoma. J. Sastre (Hospital Universitario Clínico San Carlos, Madrid. Spain).


8


FRIDAY, 14 DECEMBER 09:00-10:00 SATELLITE SYMPOSIUM. Sponsored by Merck.

5ª TABLE. OESOPHAGOGASTRIC CANCER. EVALUATION AND TREATMENT

Moderators: B. Massutí (Hospital General Universitario de Alicante. Spain). F. Rivera (Hospital Universitario Marqués de Valdecilla, Santander. Spain).

10:15-10:35 Precision medicine in oesophagogastric cancer. Limitations and opportunities. A. Bass (Dana-Farber Cancer Institute, Boston. United States).

10:35-10:55 Updates on the neoadjuvant treatment of oesophagogastric cancer. E. Smyth (Cambridge University Hospitals NHS Foundation Trust, Cambridge. United Kingdom).

10:55-11:15 Continued treatment strategy in gastric cancer. P. Jiménez Fonseca (Hospital Universitario Central de Asturias, Oviedo. Spain).

11:15-11:35 Immunotherapy in gastric cancer. M. Valladares (Hospital Universitario Reina Sofía, Córdoba. Spain).



9


10

6ª TABLE. METASTATIC COLON CANCER

Moderators: R. Salazar (ICO. Hospital Duran i Reynals, Barcelona. Spain). E. Aranda (Hospital Universitario Reina Sofía, Córdoba. Spain).

12:30-12:50 How should first-line treatment for metastatic colorectal cancer be initiated? E. Van Cutsem (Gasthusberg University Hospital, Leuven. Belgium).

12:50-13:10 Treatment after best response. Maintenance vs. intermittent treatment. D. Arnold (Instituto CUF de Oncologia, Lisbon. Portugal).

13:10-13:30 Reintroduction of treatment to progression of the disease. P. García Alfonso (Hospital Universitario Gregorio Marañón, Madrid. Spain).

13:30-13:50 Immunotherapy. M. Benavides (Hospital Universitario Regional y Virgen de la Victoria, Málaga. Spain).

13:50-14:10 Therapeutic options in refractory disease. E. González Flores (Hospital Virgen de las Nieves, Granada. Spain).

14:10-14:30 Discussion

14:30-14:35 Final conclusions and Closure

14:35-15:30 Lunch

SCIENTIFIC PROGRAM


11

GENERAL INFORMATION

VENUEVALENCIA CONFERENCE CENTREAuditorium 2Avenida de las Cortes Valencianas, 6046015 Valencia. SpainTeléfono: + 34 963 17 94 00https://www.palcongres-vlc.com/

ACCREDITATIONAll registered attendees will be able to download the certificate of attendance and the accreditation of continuing training from the web of TTD Group.

All registered attendees will be able to download the certificate of attendance and the accreditation of continuing training from the web of TTD Group. The minimum attendance required to obtain the accreditation certificate is 80% of the total duration of the activity.

Symposium accredited with 2,4 credits by the Health Professions Continuous Formation Commission fo the Community of Valencia.

LANGUAGESThe official languages of the Symposium will be English and Spanish, simultaneous translation will be available.

LUNCH December 13th Thursday, at 14:30 h Valencia Conference CentreDecember 14th Friday, at 14:35 h Valencia Conference Centre


12

GENERAL INFORMATION

CONFERENCE SECRETARIAT

SPANISH COOPERATIVE GROUP FOR DIGESTIVE TUMOUR THERAPYSusana Rodríguez FernándezC/ Téllez, 30 posterior. Piso 1º, Oficina 4.2 • 28007 Madrid. SpainTel.: +34 91 378 82 75 • Fax: +34 91 378 82 76 • Mobile Phone: +34 699 63 64 94E-mail: [email protected] • Website: www.ttdgroup.org

REGISTRATION FEES

General Registration fee: 795,00 E

Residents fee*: 597,00 E*A document attesting fulfilment of resident physician condition must be provided.

Included in the registration fee are: attendance to scientific sessions, conference materials, certificate of attendance, refreshment breaks and lunch breaks.

ACCOMMODATION

DUI Doble

Hotel Meliá Valencia ****Av. de las Cortes Valencianas 5246015 Valencia. SpainTeléfono.: +34 96 303 00 00https://www.melia.com/es/hoteles/espana/valencia/melia-valencia/index.html

107,80 e 118,80 e

Hotel Sorolla Palace****Av. de las Cortes Valencianas 5846015 Valencia. SpainTEL.: +34 96 186 87 00https://www.hotelsorollapalace.com/

93,50 e 104,50 e

Prices are per room and night. Breakfast and taxes included. Hotel room assigned on a first-come, first-served basis.

Please, check with the Conference Secretariat for availability at the hotel before the payment.


13

REGISTRATION FEE FORM OF PAYMENTRegistration fees can be paid by:

Checks payable to: Grupo de Tratamiento de los Tumores Digestivos.

Bank Transfer to: Grupo de Tratamiento de los Tumores Digestivos. Bankia. Sucursal Plaza de Castilla, 3. Madrid, Spain Account : ES29.2038.1742.28.6000604214 BIC: CAHMESMMXXXA photocopy of payment must be sent to the conference secretariat together with the registration form. Please, include the assistant name in thebank transfer.* Cancellations: Cancellations and refund request must be submitted in writing to the Conference Secretariat. There will be a refund of 50% of the total amount for cancellations received before 09 November 2018. After this date no refunds will be made. All refunds will be processed after the conference.

ACCOMMODATION FORM OF PAYMENTThe accommodation placement fee must be paid directly at the Grupo Viajabien Travel Agency

Bank Transfer to: Grupo Viajabien. Calle Zurbano 45, Planta 6ª Account Nº: ES65 0081 0189 85 0001775684 BIC: BSABESBBXXXA photocopy of payment must be sent to the conference secretariat together with the registration form. Please, include the assistant name in the bank transfer.

RENFE offers attendees at the 26 International Symposium TTD discounts of up to 30% on train jour-neys. In order to obtain the reduction authorization form, please contact the Conference Secretariat.

OFFICIAL TRANSPORT AGENTS


MAP

1 2

3

VALENCIA CONFERENCE CENTREAvda. de las Cortes Valencianas 6046015 Valencia. SPAINTel.: 963 17 94 00

1


Hotel Sorolla Palace****Av. de las Cortes Valencianas 5846015 Valencia. SPAINTel.: 961 86 87 00

Hotel Meliá Valencia ****Avda. de las Cortes Valencianas 5246015 Valencia. SPAINTel.: 963 03 00 00

2

3

Documents

VALENCIA. 13th -14th DECEMBER 2018 · 2018. 11. 23. · VALENCIA CONFERENCE CENTRE 26 VALENCIA. 13th -14th DECEMBER 2018 SCIENTIFIC PROGRAM ADVANCES IN THE TREATMENT OF DIGESTIVE