Upload
virgil-walters
View
232
Download
1
Embed Size (px)
Citation preview
“Outbreaks of epidemic typhus are rare except during periods when normal hygiene is disrupted, as in refugee camps arising from wars or natural disasters. It also occurs in some populations living in higher elevations during the colder months when louse-infested clothing is not laundered and person-to-person spread of lice is common.”
Typhus epidemics raged throughout Europe for centuries, often caused by war.
“Seventy percent of the 300,000 core troops that marched with Napoleon out of France died of typhus before reaching Moscow.”
Doxycycline “preferentially binds to bacterial (30s) ribosomes due to structural differences in RNA subunits.”
Without these proteins, the bacteria cannot reproduce within the cell, and the cells eventually die or are killed off by the immune system.
Although it is cheap and easy to produce, it has potentially serious side effects.
Used mainly in cases of drug resistant bacteria.
Brill-Zinsser disease occurs when a previously ‘cured’ patient relapses.
More mild than the initial disease
Works CitedBoard, A.D.A.M. Editorial. "Typhus (Endemic, Murine, Epidemic) Causes, History, Symptoms and Treatment Information by MedicineNet.com." Typhus. U.S. National Library of Medicine, n.d. Web. 04 Nov. 2012. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002339/>. "Brill-Zinsser Disease." TheFreeDictionary.com. N.p., n.d. Web. 04 Nov. 2012. <http://medical-dictionary.thefreedictionary.com/Brill-Zinsser disease>. Buzzle. N.p., n.d. Web. 4 Nov. 2012. <http://www.buzzle.com/img/articleImages/284893-11710-44.jpg>. "Chloramphenicol: 15 Answers." Chloramphenicol: 15 Answers. N.p., n.d. Web. 04 Nov. 2012. <http://www.usermeds.com/medications/chloramphenicol>. "Chloramphenicol Capsules." Netdoctor. N.p., n.d. Web. 04 Nov. 2012. <http://www.netdoctor.co.uk/infections/medicines/chloramphenicol-capsules.html>. "Chloramphenicol." Wikipedia. Wikimedia Foundation, 11 Feb. 2012. Web. 04 Nov. 2012. <http://en.wikipedia.org/wiki/Chloramphenicol>. "Disease in History." Disease in History. N.p., n.d. Web. 04 Nov. 2012. <http://www.science-projects.com/Pathlets.htm>. "Doxycycline." (Equine Pharmacy (Rx). N.p., n.d. Web. 04 Nov. 2012. <http://www.valleyvet.com/ct_detail.html?pgguid=6ac701b4-fe49-402b-82e2-f5cac20b06eb>. "File:Epidemic Typhus Burundi.jpg." Wikipedia. N.p., n.d. Web. 4 Nov. 2012. <http://drugline.org/img/ail/893_898_1.jpg>. "Image:Rickettsia Prowazekii.jpg." Academic Kids Encyclopedia, n.d. Web. 4 Nov. 2012. <http://www.academickids.com/encyclopedia/index.php/Image:Rickettsia_prowazekii.jpg>. “Interferes with Protein Synthesis." Sigma-Aldrich. N.p., n.d. Web. 04 Nov. 2012. <http://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=14572899>. Ketcham, Sandra. "How to Cure Typhus." EHow. Demand Media, 20 July 2009. Web. 04 Nov. 2012. <http://www.ehow.com/how_5197044_cure-typhus.html>.
Works Cited (Cont.)"Membrane Transport System (Transporters) in Rickettsia Prowazekii MadridE." Membrane Transport System (Transporters) in Rickettsia Prowazekii MadridE. N.p., n.d. Web. 04 Nov. 2012. <http://www.membranetransport.org/transporter2.php?oOID=rpro1>. N.p., n.d. Web. 4 Nov. 2012. <http://img.tfd.com/wn/61/6687B-stupor.gif>. N.p., n.d. Web. 4 Nov. 2012. <https://labtestflorida.s3.amazonaws.com/images/bigimage/completebloodcount.jpg>. N.p., n.d. Web. 4 Nov. 2012. <http://www.pc.maricopa.edu/Biology/rcotter/BIO%20205/LessonBuilders/Chapter%209%20LB/provsEukRibosomes.jpg>. "Order Doxycycline, Order Cheap Generic Doxycycline, Order Cheap Generic Doxycycline Online from World-drugs.net." Order Doxycycline, Order Cheap Generic Doxycycline, Order Cheap Generic Doxycycline Online from World-drugs.net. N.p., n.d. Web. 04 Nov. 2012. <http://world-drugs.net/generic_doxycycline.php>. "Rickettsia, Ehrlichia, Coxiella and Bartonella." Rickettsia, Ehrlichia, Coxiella and Bartonella. N.p., n.d. Web. 04 Nov. 2012. <http://pathmicro.med.sc.edu/mayer/ricketsia.htm>. "Rickettsial Diseases, including Typhus and Rocky Mountain Spotted Fever." Rickettsial Diseases, including Typhus and Rocky Mountain Spotted Fever. N.p., n.d. Web. 04 Nov. 2012. <http://textbookofbacteriology.net/Rickettsia_2.html>. "Tetracycline - Antimicrobial Properties." Tetracycline - Antimicrobial Properties. N.p., n.d. Web. 04 Nov. 2012. <http://www.chm.bris.ac.uk/motm/tetracycline/antimicr.htm>. "TheOnlineClinic." Doxycycline. N.p., n.d. Web. 04 Nov. 2012. <http://www.theonlineclinic.co.uk/doxycycline.asp>. "Typhoid and Typhus." Typhoid and Typhus. N.p., n.d. Web. 04 Nov. 2012. <http://www.nepalinternationalclinic.com/typhoidmain.html>. "Typhus - Geographical Occurence." Typhus - Geographical Occurence. N.p., n.d. Web. 04 Nov. 2012. <http://sprojects.mmi.mcgill.ca/tropmed/disease/typhus/geo.htm>. "Typhus (Endemic, Murine, Epidemic) Causes, History, Symptoms and Treatment Information by MedicineNet.com." MedicineNet. N.p., n.d. Web. 04 Nov. 2012. <http://www.medicinenet.com/typhus/article.htm>. "Typhus-us-heatmap." N.p., n.d. Web. 4 Nov. 2012. <http://b1969d.medialib.glogster.com/media/2cabe2d6bdc7bb8bff584591a2a357b66d86542fb5858b9cbc5467dac42f8aa6/typhus-us-heatmap.jpg>. WebMD, n.d. Web. 4 Nov. 2012. <http://img.webmd.com/dtmcms/live/webmd/consumer_assets/site_images/media/medical/hw/n5551334.jpg>. Wikipedia. N.p., n.d. Web. 4 Nov. 2012. <http://en.wikipedia.org/wiki/Typhus>.