Cau Clinicopathologic Characteristics Among all patients, 528 (72.8%) presented with local dis- ease, compared with 197 (27.2%) patients with metasta- sis. Tumor size was known for 406 patient cases (56.0%), with 164 (22.6%) patient cases having tumor size <8 cm, and 242 (33.4%) patient cases having tumor size equal to or greater than 8 cm. Patient cases with metastatic disease had a higher proportion of large tumors (8 cm and greater) than did patient cases without metastatic disease (76.8% vs 54.3%, P < .0001). Furthermore, a greater proportion of whites had tumor size smaller than 8 cm, as compared with Others and Hispanics (46.6% vs 31.8% and 33.6%, respectively, P ¼ .02). Large tumor size was not associated with rate of low SES, chemotherapy, radia- tion therapy, or surgical intervention. Location of disease at initial presentation was as follows: 34 (4.9%) head/ neck, 121 (17.4%) chest/abdomen, 301 (43.3%) extrem- ities, 61 (8.8%) spine, and 178 (25.6%) pelvis, which include the sacrum according to CCR site coding. There were 544 (75%) patient cases with skeletal involvement and 181 (25%) with nonskeletal involvement. Patient cases with pelvic involvement had a statistically higher fre- quency of metastasis at diagnosis compared with patient cases with extremity or other location involvement (36.5% vs 19.6% and 25.9%, respectively; P ¼ .0002). Pelvic involvement also had a higher rate of large tumor size than did patient cases of extremity or other location involvement (73.0% vs 60.5% and 45.1%, respectively, P < .00 01). Treatment profile for all patients included 339 (46.7%) who did not receive radiation, and 386 (53.2%) who did receive radiation. Similar rate of radiation ther- apy was seen across the major racial/ethnic groups (45.7% Others vs 56.5% white vs 49.8% Hispanic, P ¼ .1). There was no significant difference in rate of surgical interven- tion (P ¼ .12), metastatic disease (P ¼ .09), SES (P ¼ .23), or tumor size (P ¼ .5) between patient cases that received radiation and those that did not. However, radiation was given more commonly to patient cases with pelvic and axial involvement, compared with extremity involvement (58.43% and 57.41% vs 48.5%, respec- tively, P ¼ .048). The majority of patient cases received chemotherapy, 664 (93%), with only 50 (7.0%) patient cases that did not. When comparing the 2 age groups, a significantly greater proportion of the adult group did not receive chemotherapy (12.7% adults vs 1.6% children, P
Cau Clinicopathologic CharacteristicsAmong all patients, 528
(72.8%) presented with local dis- ease, compared with 197 (27.2%)
patients with metasta- sis. Tumor size was known for 406 patient
cases (56.0%), with 164 (22.6%) patient cases having tumor size
