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Symptoms: common and less common Lyme Disease Misdiagnosed as Photos: Lyme Rash Bartonella Rash Lyme Under the Scope How is Lyme Transmitted? How is Lyme

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Symptoms: common and less common Lyme Disease Misdiagnosed as Photos: Lyme Rash Bartonella Rash Lyme Under the Scope How is Lyme Transmitted? How is Lyme Diagnosed? Treatments Options: Anti-biotics Botanicals Precious Metals Nutrition/Gastro Intestinal Hormonal Dental Heavy metals Co-Infections Parasites Fungus/Yeast Herxheimer Reactions Hyper coagulation Explaining the Sodium / Potassium Pump Treating Lyme Disease Slide 2 By Steve Hines, N.D. N.E. Co-Founder with Dr. Elio Rivera, M.D. of Slide 3 IMHO - In My Humble Option Slide 4 fatigue joint pains muscle pains / tight muscles headaches/migraines hormone disturbances thyroid problems multiple chemical sensitivity fasiculations-muscle twitches tinnitus-ringing in the ear low grade fever night sweats sleep pattern disturbance most all mental/nervous disorders Symptoms: Common and Not So Common Slide 5 Auto Immune: Fibromyalgia, Lupus, Chronic Fatigue Syndrome, Multiple Sclerosis Arthritis/Bone/Joint: Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Osteoarthritis, Osteoporosis Neurological: Parkinson's, Autism, Migraine Headaches, Dementia, Alzheimer, ALS Digestive: Gastric Reflux, Irritable Bowel, Constipation, Crohns Disease, Hiatal Hernia Dermal: Scleroderma, Eczema, Psoriasis Endocrine: Hashitmotos-hypothyroidism, Cushings or Addisons disease Cancer: Lymphoma, Leukemia Emotional: Depression, Anxiety Attacks, Panic Disorders. OCD Blood Sugar: Hypoglycemia, Diabetes And a couple hundred more! My Personal Favorite: Nothings wrong - Its all in your head Lyme Disease Often Misdiagnosed as: Slide 6 Lyme Disease a Multi-Faceted Problem Mental / Nervous: Depression, Anxiety, OCD Gastric Disturbances: Food Allergies, IBS, IBD, Constipation Nutritional Deficiencies: B12, B1, Folate, Vit D Hormonal Disturbances: Estrogen Dominance Adrenals, Thyroid Dental Toxicity: Root Canals Mercury Fillings Electrolyte Disturbances: K+ / MG++ Lyme Disease Slide 7 Slide 8 Slide 9 Slide 10 Slide 11 Slide 12 Slide 13 Slide 14 Slide 15 Slide 16 Slide 17 Slide 18 Slide 19 Mosquitoes, Ticks, Horse flies: 22% of horse flies, deer flies and mosquitoes are infected with Borrelia and coinfections in endemic areas! The etiologic agent of Lyme disease in deer flies, horse flies and mosquitoes, J Infect Dis 154 (1986), 355358, LA Magnarelli, JF Anderson, AG Barbour, In utero transmission: Borrellia has been shown to be passed from mother to baby during gestation. Blood Transfusion: This obviously possible because blood banks do not test for Lyme and co-infections. Sexual Transmission: Spirochetes have been cultured out of saliva, semen, the oral mucosa as well as vaginal secretions. Breast feeding moms: Spirochetes can be transmitted through breast milk. Slide 20 Western Blot: deemed Standard of Care yet still results in 30-50% false negatives. ELISA: The least sensitive test. Usually used as a rapid screening test for acute stage. Very poor test. Culture: The most accurate, but takes months to culture Spirochetes. Spirochetes grow very slowly. Tissue biopsy: tissue culture rarely produce positive test. PCR (polymerase chain reaction): very accurate, if enough antigen is available. Rarely is there enough antigen! IMHO Preferred Test: Spiro Stat Technologies / www.spirostat.com How is Lyme Disease Diagnosed? Laboratory test of blood and urine Slide 21 Rapid identification of a variety of spirochete bacteria and common Lyme related co-infections with high sensitivity of detection. Spiro Stat uses modern molecular assays: Molecular diagnostics are well known to be highly sensitive and specific With molecular methods diagnostic results are not skewed when a patient is receiving immune suppressing medication- looking for Bacterial DNA, not antibodies! Results not dependent on organism viability Detection of non-culturable and slowly proliferating organisms A single, inexpensive two stage testing panel: PCR Component- cutting edge/proprietary methodology and reagents Molecular Sequencing Component-most accurate validation/identification available Spiro Stat Technologies A New Era for Detecting Lyme and Common Co-Infection Organisms Slide 22 Anaplasma phagocytophila Bartonella henselae Borrelia afzelii Borrelia burgdorferi Borrelia garinii Borrelia hermsii Borrelia lonestari Borrelia parkeri Brachyspira aalborgi Brachyspira hyodysenteriae Coxiella burnetii Ehrlichia chaffeensis Additional test available for Babesia microti. Spiro Stat Technologies Diagnostic Panel Francisella tularensis Leptospira biflexa Leptospira borgpetersenii Leptospira interrogans Leptospira kirschneri Leptospira wolbachii Mycoplasma fermentans Mycoplasma hyopharyngis Ricketsia species (9 species) Treponema carateum Treponema denticola Treponema pallidum Treponema pertenue Slide 23 Anti-biotics: Standard of Care 28 days of anti-biotics Anti-biotics are quite effective in most cases however there are many side effects and the incidence of reoccurrence is very high. Some side effects are: Yeast overgrowth, Nausea, Reflux, Headaches, Liver toxicity, Hematological changes such as IPT, low RBCs, and Anemia. Botanicals: Herbs are gaining prominence for many reasons. No prescription necessary, highly effective except in Neuro-Borelliosis, No yeast infections, inexpensive. We are still learning which botanicals are the most effective for each particular strain of organism. IMHO Best Option: Hopes clinical experience has shown a combination of anti-biotics and herbs has been far superior than either one alone. Treatment Options Slide 24 At Hope, we generally do not jump to anti-biotics as a first line defense but after we have treated as well as we can with botanicals, minerals and precious metals. The primary exception at this time would be obvious Neuroborreliosis and Lyme carditis. These are very dangerous cases with potential clinical side effects such as seizures and Atrial Fibrillations and heart attacks. Anti-biotics used effectively for Borrelia: Rocephin, usually 1 gram bid, I.V. is most effective. In Mexico, we use Rocephin with DMSO. Flagyl or Tindamax to kill the cyst form of the spriochette. We also use Flagyl I.V with DMSO. Zithromax and Minocyclin are valuable tools. We always give Nystatin 500,000 units bid and 1 foil packet of HLC (probiotic) by Pharmax when using anti-biotics. Fungal infections are rare while on this regime. Treatments: Anti-biotics Standard of Care 28 days of Doxycycline Slide 25 At Hope, treatment begins with 3 drops of each in 1 pint of water, sip slowly over 2 hours. Over the next 12 days increase dose a drop or 2 daily. Some people feel so poorly that they cannot bear increasing the dose anymore. This is fine simply stay at the tolerable level until symptoms diminish. Then begin increasing dose again. At Hope, the treatment periods are 12 days on and then 3 days off. After the first 12 days on Samiento/Banderol combo and a 3 day rest, then begin the Cumanda cycle. IMHO Preferred Supplement: NutraMedix www.nutramedix.comwww.nutramedix.com Slide 26 As with the Samiento/Banderol combo, start with 3 drops in a pint of water, sip slowly over 2 hours. Then each day add a drop or 2 for the next 12 days or up to the level where the Herxheimer is too uncomfortable. This happens often. After 12 days take 3 day break and the switch back to the Samiento/Banderol combo and repeat the cycle. The ultimate goal is 90 drops of each botanical with no pain. If you can take 90 drops of these botanicals with no more pain this is a good sign you have substantially lowered the total body burden of bacteria. IMHO Preferred Supplement: NutraMedix www.nutramedix.comwww.nutramedix.com Slide 27 If you suspect viral involvement Takuna is an excellent anti-viral. At Hope, treatment is with 30-40 drops a day in a pint of water for 2 months. IMHO Preferred Supplement: NutraMedix www.nutramedix.comwww.nutramedix.com Slide 28 Olive Leaf Extract has many properties, anti-amoeba, anti-viral, anti-fungal, anti-mycoplasma. At Hope treatment is with 1000 mg bid. IMHO Preferred Supplement: Sea Gate. www.seagateproducts.com. Sea Gate grows their own olive trees and harvest fresh leaves. This is a very potent product. www.seagateproducts.com Slide 29 Most professionals recommend 20 drops 2-3 times a day. Start low and work up to target dose. Many patients do get a rash, The rash will generally last from 7-14 days. This rash can be severe! Be aware! Lomatium does have anti-viral and anti-fungal properties. Lee Cowden believes many patients who have skin reactions to this herb is do to an undiagnosed chronic measles infection. Be very respectful with this herb! Preferred supplement: Generation II Barlow Herbal Specialties www.barlowherbal.com www.barlowherbal.com Slide 30 Meso Silver has become one of Hopes most effective tools for not only spirochetes but many co-infections seem to be responding also. We start with 1 oz. daily and work up to 2 oz. 3-4 times daily. The Herxheimer can be severe, dont go to fast! IMHO Preferred supplement: Meso Silver www.purestcolloids.com/mesosilver.htm Slide 31 Poor nutrition and gastric infections greatly contribute to hormonal imbalance. Often there are other infections such as amoebas, tape worms, ascaris, trichinella and fungal/yeast infections. The panel Hope runs is the GI-02 panel. We usually add salivary SIg-A to the panel to test the gastric immune system. The test includes major food allergies: gluten, soy, egg, milk. IMHO Preferred Test: Diagnostechs / www.diagnostechs.comwww.diagnostechs.com Slide 32 Fighting disease takes a lot of energy. This is a commodity that most patients fighting a disease need in abundance. Hope recommends a strict diet that contains zero artificial anything, and zero sugar or grains, a no disaccharide diet. The purpose of the this type of diet is to heal the GI tract and minimize the inflammatory process, inhibit the growth of yeast, normalize peristalsis and avoid the most common allerge

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