Subject index

Acetylcholine 25 Acetylcholinesterase 25, 41-43 Alumininium 48 "ALZ 50" 13 Amyloid (in senile plaques) 4 - methods for 30 - vascular 35 Amyotrophic lateral sclerosis 20 Argyrophilic grains 20 Arteritis (possible relationship to AD) 36 Astrocytes 4 -' in senile plaques 27

Beta/ A4 protein 30 Boxing 44,47

Catecholamines 26 Choline-acetyl-transferase 25 Cytoskeleton (in normal neuron) 7

Dementia (relationship with histology) 6 Down syndrome 45 - plaque formation in 45 "Drusige Entartung" 35

Electron microscopy 1, 2, 3 Encephalitis - neurofibrillary tangles I N 1 Eosinophilic rodlets (Hirano bodies) 3

Familial Alzheimer 47

Glial fibrillary acidic protein 8 Granulovacuolar degeneration 1, 3, 15

Hemorrhage - (cerebral in vascular amyloidodis) 5 Hereditary (familial) Alzheimer 37 Heredity 47 Hirano bodies (eosiniphilic rodlets) 3 History 1

Immunoblot (Western blot) 9 - neurofilament proteins 9

Iron in microglia 50

Lewy bodies 20

Microglia 4 - in senile plaques 28 - methods for 28 - role in plaque formation 44 Microtubule associated proteins 8 Microtubules (in normal neuron) 22

Neurites (neuronal processes) 22 Neurofilaments (in normal neuron) 8 - chemistry 8 Neuropil 22 Nomenclature of plaques 32

Paired helical filaments 1, 2, 3, 22 Parkinson's disease 20 P-component (of amyloid) 31 Phosphorylation (neurofilaments) 9 Pick's disease 17 Plaque formation (stages) 40, 41, 44 Progressive supranuclear palsy 18

Senile plaque 4, 22 - methods for 33 Serotonin 26 "Slow virus" disease 46 Synaptophysin (relation to dementia) 6

Tangle formation, stages 38 Tangles, neurofibrillary 1, 2 - histological demonstration 13, 14 - extracellular 17, 38 "Tau"-proteins, isoforms 7,10 Trauma 47 Twins 48

Ubiquitin 15, 16, 22, 35

Viruses 42