R&DIN SINGAPORE

SINGAPORE BUSINESS ENVIRONMENT

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OF R&D IN SINGAPORES$7.6B R&D Expenditure in 2013

Private

60%Higher Education

17%

11%

Public Research Institutes

12%Government

A national priority

S$16.1b national budget for research, innovation and enterprise from 2011 to 2015

Growing pool of talent

30% increase in number of Research Scientists and Engineers from 2007 to 2013

World-class IP Regime

Ranked 4th in the world and 1st in Asia for IP protection by the World Economic Forum’s Global Competitiveness Report 2015 / 2016

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COMMITMENT TO R&D

010002000300040005000600070008000

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Economic Strategies Committee 2010 Recommendations:

INNOVATION as one of the three basis of economic growth

“Research and Development (R&D) has become very important to our economy because

it helps us to renew our industries and create new markets. It helps our companies,

particularly the small ones, to upgrade productivity. It creates good jobs for workers,

and through new products and services, improve the lives of Singaporeans.”

Mr Lee Hsien Loong, Prime Minister, 2015

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R&D FRAMEWORKIN SINGAPOREA comprehensive ecosystem

National Research Foundation (NRF)

Research, Innovation and Enterprise Council (RIEC)

Trade & Industry Education Health Defense

Economic Development Board

(EDB)

Academic Research

Council

National Medical

Research Council

Defence Science And

Technology Agency

(DSTA)

Agency for Science, Technology and

Research (A*STAR)

Corporate Research Centres

Institutes of Higher

Learning

Hospitals & Medical

Centres DSO National

Laboratories

A*STAR Research Institutes

Supports an entire range of research from investigator-led to industry research

A one-stop destination for R&D at different phases

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OVERVIEWAN INTEGRATIONR&D PLATFORMA clustering of public & private Research Institutes

A world class research hub – Designed as an entire Integrated Innovation Ecosystem

BIOPOLIS (Biomedical Plug & Play Campus) +

FUSIONOPOLIS (Science & Technology Hub)

- 3,000 man private and public R&D campus

- Multiple research disciplines from

bio-imagining to microelectrons

- Access to scientific talent and collaborators

- Access to shared facilities & services

- Low start-up cost

- Facilitates open innovation & collaborations

Phase 2

Phase 1

Phase 3

Phase

4

Bioprocessing

Technology Institute

(BTI)

Institute of

Bioengineering and

Nanotechnology (IBN)

Genome Institute

of Singapore

(GIS)

Bioinformatic

s Institute (BII)

Institute of

Molecular and Cell

Biology (IMCB)

Singapore Institute for Clinical Sciences

(SCIS)

Institute of Medical

Biology (IMB)Chromos

Helios

Data Storage Institute (DSI)

Institute of Materials and Engineering (IMRE)

Institute of Infocomm Research (I2R)

Institute of Materials and Engineering (IMRE)

Institute of High Performance Computing (IHPC)

Singapore Institute of Manufacturing Technology

(SIMTech)

Institute of Microelectronics (IME)

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CONSUMER INSIGHTS CAPABILITIES

6 of Top 10Market Research firms have

regional centres In Singapore,

employing ~2,000 employees

ACI:A S$77m National Institute

for leading pan-Asian consumer behaviour and

Methodology research

and education

Analyticsto provide business insights

* Refer to our consumer insights presentation for more info

Interdisciplinary Research

Pan-Asian consumer behavior (e.g. similarities and differences) and methodologies (e.g.

neuroscience and qualitative) research

Education

MSc, PhD and Executive Education programmes in Asian consumer research

Collaboration

With renowned academia and industry practitioners

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SMART NATIONSmart Nation Platform to enable Smart Homes, Buildings, Cities

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* Refer to our smart sustainable cities presentation for more info

Secure government-owned sensor network for collection of urban big data

COLLECT

Communications infrastructure strengthened by street level connectivity

CONNECT

Data analytics to enable new services & applications for housing estates, mobility, healthcare, safety & security etc.

COMPREHEND

Smart Nation testbed @ JLD

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LARGE SCALEINTEGRATED LIVING LABS

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* Refer to our Smart Sustainable Cities presentation for more info

Smart & Sustainable Towns:

Integrated Estate Management Systems, ICT integration, Energy management

Residential

HDB Eco Towns

Jurong Island v2.0:

Pervasive sensing industrial efficiency

Industrial

Jurong Island

Greenest campus in the world:

Campus-level energy management, e-mobility, ICT integration

Education / Research

NTU EcoCampus

Sustainable, Smart and Connected Business District:

Building energy management, urban logistics, e-mobility

Mixed Development

Jurong Lake District

Green Business Park for the tropics:

Energy management, green building technologies

Green Industries

Cleantech Park

Innovation Hub:

Green building technologies, mobility, estate-level energy management solutions

Commercial

One North

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RESEARCHINSTITUTES

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RESEARCH INSTITUTES

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Ministry of Trade & Industry

EDB A*STAR

Biomedical (BMRC)

Science & Engineering(SERC) A*GA A*JC ETPL Corp

Grp

ICES IMRE IHPC DSI IME I2R SIMTechNMC

BII BTI GIS IBN IMB IMCB SICS

Bioinfomatics Bioprocessing GenomeStudies

Bionano-tech MedicalBiology

Molecular &Cell Biology

Clinical Sciences

Chemicals Materials Computing Memory Electronics Communications ManufacturingMetrology

A*STARSERC

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INSTITUTE OF CHEMICAL& ENGINEERING SCIENCES (ICES)

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Research in chemistry and

chemical engineering

sciences, from exploratory

research to process

development, optimisation

and problem-solving.

- Enhance taste- Cost-down processes

Research Areas

- Industrial Technology

- Organic Chemistry

- Process Science and Modelling

- Crystallisation & Particle Science

- Polymer Engineering and Catalysis

Facilities

- Batch and continuous reactors

- Kilo / pilot scale lab

- Fermentation vessel

Application Examples

- Highly efficient and green production processes to make flavours, ingredients from biomass / feedstock

- Taste-masking, encapsulation and controlled release.

Industry Collaboration

- Biotech-production of edible acids, cost-effective route for emulsifier production and taste-masking formulation

- Top FMCG MNC’s and local ingredient companies

Dr Keith Carpenter,

Executive Director

Industry Collaboration

Industrial Coating & Packaging

Consortium (ICAP)

- Non-competing companies (e.g. Nestle) work with IMRE

- Patented clay modification technology to produce barrier packaging material

INSTITUTE OF MATERIALRESEARCH & ENGINEERING (IMRE)

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Capabilities include materials

analysis & characterisation,

design, patterning and

synthesis.

- Pro-long shelf-life & freshness in tropical environment

- Cost-down and sustainable packaging

- Food safety in Asian food matrix and tropical environment

Research Areas

- Sensing materials & systems

- Functional films

- Encapsulation technology via self-assembly

- Green Packaging

Application Examples

- Sensing materials & systems for food safety in the Asian food matrix

- Active and intelligent packaging –ensure freshness of foods

- Packaging design – increased volume to surface area to reduce cost

Prof Andy Hor,

Executive DirectorPresident, Federation of Asian Chemical

Societies

INSTITUTE FOR HIGHPERFORMANCE COMPUTINGEfficient, insightful and applied analytics technology and techniques

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Efficiency – High

Performance Computing

Creation of a high

performance cloud

Workflow management

for Big Data

Insight – Large Scale Modelling,

Simulation, Visualization

Complex Systems

Understanding emergent andself-organizing systems

Geometrical Modelling

Creation and management of 3D models for research and analysis

Computational Social Cognition

Creation of computational modelsof social behaviour between humans

Application – Bringing

technology to life

Environment

- Predicting rainfall intensity- Traffic simulation and

prediction

Biomedical

- Analysis of Phenotype data

Public Health

- Real-time epidemic simulations, i.e. H1N1

DATA STORAGEINSTITUTE (DSI)

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NON-VOLATILE MEMORIES

- STT-MRAM

- PCRAM

- RRAM / Memristor

- Coding and Signal Processing

- NVM Storage Controller

- NVM Tester

ADVANCED CONCEPTS

& NANOTECHNOLOGY

- Nanofabrication

- Spintronics

- Plasmonics

- Photo-Electronics

- Metamaterials and Small

Particle Physics Research

DATA CENTRE

TECHNOLOGIES

- Green Data Centre

technologies, NVM and

Enterprise Hybrid Integration

- Petabyte Genome Data

Centre Platform

- Large scale data management

- In-memory computing and

analytics

- Security

DRIVE SYSTEMS AND

TECHNOLOGIES

INSTITUTE OFMICROELECTRONICS (IME)To be a world-class research institute in advancing microelectronics technology

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One of the world’s leading microelectronics

researchers, a professor at the Microelectronics

Research Centre, the University of Texas at Austin,

has been appointed as the new Executive Director

of IME with effect from 1 January 2005.

Recent R&D efforts include: 10 Gbps optical communication IC and microphotonics for optoelectronics integrated circuits

Prof Dim-Lee Kwong

Staff

269Students

115University Faculty

15(including 62 PhD,

13 Masters)

INSTITUTE OFMICROELECTRONICS (IME)To be a world-class research institute in advancing microelectronics technology

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Research Areas

Integrated Circuits & Systems

- Analog & Mixed Signal IC

- RF & UWB IC

- mmWave & RF Noise Modeling

Semiconductor Process Technologies

- Novel Materials, Processes & Integration

Microsystems, Modules & Components

- Microsystems Design

- Electronics, Si Photonics & MEMS packaging

- 3D Wafer Level Through Si Via

Bioelectronics

- Patch Clamp & Si MicroFluidics

- Si-Based Bio-Sensors

- Lab-on-Chip

Sensors & Actuators Microsystems

- MEMS / NEMS Devices & Applications

- CMOS Integration

Nano Electronics & Photonics

- Nano-Electronics

- Si-Microphotonics

- Si-Based Light Sources

INSTITUTE FORINFOCOMM RESEARCHTechnologies and techniques to unlock value from data

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Data Mining

- Machine learning anddatabase systems

- Text mining

- Privacy Preservation

Security

- Cryptography

- Mobile device security

- Digital forensics

Computer Vision &

Image Understanding

- Video surveillance for behaviour and event understanding

- Object and scene recognition

- Gesture and facial expression recognition

- Video content indexingand retrieval

Human Language

Technologies

- Machine Translation of Southeast Asian Languages

- Speech, Speaker and Language Recognition

- Rich Transcription

- Speech synthesis

- Audio Keyword mining

- Spoken information and Document retrieval

Collaborations

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To promote green packaging applications by creating a platform for Innovation of packaging ideas, materials and process technologies

Objective

Product owners; packaging design and innovation, equipment, materials suppliers, manufacturing, waste management

Targeted industrial clusters

Build up a partnership platform for innovation with MNCs and OEMs as leaders in green packaging implementation, and SMEs and suppliers as solution providers.

Initiative Strategy

School of Materials Science & Engineering

- Capabilities in computational material science,

nanomaterials, material and structural analysis

- Research include utilising microalgae for biodegradable packaging materials

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Current Activities on Green Packaging

Packaging as a Service

- Packaging security, for example Radio Frequency

Identification (RFID) returnable packaging

Green Packaging Materials Development

- Biopolymeric materials for packaging applications

- Waste-to-packaging solutions

- Interactive packaging to minimise wastage

Process Development for Green Packaging

- Natural fibre based biocomposites packaging

- Process development of packaging materials with

improved barrier performance

Information Communication

- Carbon footprint assessment of packaging materials

- Life-cycle assessment of packaging / product

Testing of Green Packaging

- Testing of packaging integrity

- Packaging functionality (mechanical and thermal)

evaluation through Finite Element Analysis

- Health monitoring of biocomposite packaging

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SUPPORTING IMAGINGAND MODELLING CAPABILITIES

Biological and animal models for human

development and nutrition studies.

Food molecule interaction and production

models for food formulation and production.

- Speed-up R&D process and reduce costs

of R&D

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Supporting Research Institutes

- Singapore Bio-Imaging Consortium (SBIC)

- Institute of High Performing Computing (IHPC)

- Institute of Chemical and Engineering Sciences (ICES)

Application Examples

- SBIC: Pre-clinical animal models for diabetes (insulin resistance), obesity (leptin resistance), neurodegeneration (AD, PD), etc.

- IHPC: Hair strand model

- ICES: Fluid Dynamics model in manufacturing process

A*STARBMRC

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INSTITUTE OF BIOPROCESSING& NANOTECHNOLOGY (IBN)

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IBN links multiple disciplines

across engineering, science &

medicine to improve healthcare

and quality of life.

- Enhance taste- Cost-down processes

Research Areas

- Nanomedicine

- Green Chemistry and Energy

Application Examples

- Highly efficient and green synthesis of flavours, ingredients from biomass/feedstock

- Enhanced delivery of nutrition to various body parts

- Taste-masking

Industry Collaboration Examples

- Ingredients that conjugate with active compounds in food to mask unpleasant flavours

- Top FMCG company

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Prof Jackie Ying,

Executive DirectorMaterials Research Society (MRS)

fellow. Editor-in-Chief of Nano Today,

ranked 2nd among 66 such journals.

IMB’s research activities range across stem cells, development and differentiation, skin biology, cancer and genetic diseases.

The study of molecular changes leading to

increasing cell specialisation and complexity in

the context of human tissues and diseases will

lead to novel therapeutic strategies for improved

quality of life.

INSTITUTE OFMEDICAL BIOLOGYSkin research to understand the human ageing process

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Skin Cell Bank has research collection of cultured skin cells of ethically- approved derivation taken from

- Surgical waste from healthy individuals or- Ethically-approved biopsies of specific disorders, or- Surplus cells from previous ethically-approved projects

Bank is generated and managed to professional standards by dedicated research staff.

Skin samples are keratinocytes and fibroblasts from Asian subjects, across a range of body site, age, ethnic group and sex.

IMB’s Skin Cell Bank

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Potential application: Understanding the differences between the Asian and Western phenotypes, propensity towards pigmentation, ageing etc.

INSTITUTE OFMEDICAL BIOLOGYSkin research to understand the human ageing process

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Skin Research Experts

Prof Birgit LaneExecutive Director, IMB

Prof Paul L. BigliardiExperimental Dermatology

Dr Colin StewartDevelopment

Regenerative Biology

Dr Bruno ReversadeHuman Embroylogy

Part 1

Pregnant mother and birth cohort of 1,200. Deep phenotyping of mothers and babies, to producea wealth of data.

Part 2

Aims to discover effective prevention and early

intervention strategies to reduce burden of metabolic diseases e.g. obesity and type 2 diabetes.

SINGAPORE INSTITUTEFOR CLINICAL SCIENCES (SICS)Addresses impact of chronic metabolic diseases in Singapore/Asia

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Prof Peter Gluckman,

Programme DirectorFor Growth Development and Metabolism, “GDM”

Research Areas

- Allergies

- Tissue & Cell biology

- Neurocognition

- Epigenetics

- Human endocrinology

- Clinical nutrition research

- Rodent & Primate Behaviouraland Metabolic Models

Research Examples

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Asian Cohort Study of newborns and children

during the first 6 years of their lives.Dr Judith Swain,

Executive Director

Observational epidemiology studies coupled

with pre-clinical and clinical techniques, with

emphasis on Epigenetics.

CLINICAL NUTRITIONRESEARCH CENTRE (CNRC)Part of the Singapore Institute for Clinical Sciences

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World’s 1st research centre on Asians’

nutrition need.

- Address questions on nutrition across various life stages and the impact of nutrition on disease management, specific to the Asian diet & disease profile

- Whole body nutrition studies

Prof Jeya Henry,

Director, Human

Nutritional Sciences.

Leads a team of ~20 in CNRC

Research Areas

- Food-nutrient interactions

- Energy balance and body weight control

- Glycaemic control

- Clinical Nutrition

- Specialty nutrition (elderly, women, and clinical nutrition)

Facilities

- Calorimeters (1st in Asia) –whole body, bomb, indirect, etc

- Body Composition Imaging

- Specialised lab & equipment

- Other monitoring capabilities

CLINICAL NUTRITIONRESEARCH CENTRE(CNRC)Part of the Singapore Institute for Clinical Sciences

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Industry events

Regular events to share

nutrition knowledge:

- ABBOTT Diabetes Care Scientific Summit 2012

- 13th ASEAN Food Conference

- Collaboration with SICS, A*STAR & DANONE –Seminar on Dietary Intake & Nutrition status of Toddler

R&D Examples

- Impact of vitamin A & C on bioavailability in the presence of other nutrients

- Developing a fat with reduced disease risk

INSTITUTES OFHIGHER LEARNING

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- 14 faculties & schools

- 3 campuses, 6 overseas

colleges + upcoming Utown

- 25,000 undergrads, 8000

postgrads

- Research-intensive university

- #26 in the Times Higher

Education World University

rankings 2015

- Global education: partnerships

with overseas universities for

dual degrees, student exchange,

summer programs

NATIONALUNIVERSITYOF SINGAPORE

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3 Research Centres of Excellence

- Cancer Science Institute of Singapore

- Centre for Quantum Technologies

- Research Centre of Excellence in Mechanobiology

26 university-level research institutes

and centres

Kent Ridge

OutramBukit Timah

University Town

- 4 colleges

- Business

- Engineering

- Humanities, Arts and Social

- Science

- 23,000 undergraduates

- 10,000 graduates

- 3,000 teaching and research staff

- 12 university-level research institutes

NANYANGTECHNOLOGICALUNIVERSITY

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2015: Ranked 13th in the QS World University Rankings and named world’s fastest-rising young university by Times Higher Education

Extensive global partnerships (CMU, Cambridge, Imperial, TUM, Peking University, Waseda, etc.)

CAMPUS FOR RESEARCH EXCELLENCEAND TECHNOLOGICAL ENTERPRISE(CREATE)

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CREATE campus (NUS and NTU partnering other universities)

Berkeley Education Alliance for Research in Singapore (BEARS)

Cambridge Centre for Advanced Research in Energy Efficiency in Singapore (CARES)

Energy and Environment Sustainability Solutions for Megacities (E2S2)

Nanomaterials for Energy and Water Management (NEW)

Cellular and Molecular Mechanisms of Inflammation (NUS-HUJ-CREATE)

The Singapore-ETH Center for Global Environmental Sustainability (SEC)

Singapore-MIT Alliance for Research and Technology (SMART) Centre

Singapore-Peking University Research Centre (SPURc) for a Sustainable Low-Carbon Future

Technische Universität München (TUM) – CREATE Centre for Electromobility

Singapore-Technion Alliance for Research and Technology (START) for Regenerative Medicinein Cardiac Restoration Therapy

Involvement from

Berkeley, NUS, NTU

Cambridge, NUS, NTU

Shanghai Jiao Tong, NUS

Hebrew University of Jerusalem (HUJ),Ben-Gurion University of the Negev, NTU

HUJ, NUS

ETH, NUS, NTU

MIT, NUS, NTU

Peking University, NUS, NTU

TUM, NTU

Technion, NUS, NTU, NUHS

Research COEs in collaboration with foreign universities

- Established in partnership with Massachusetts

Institute of Technology and Zhejiang University

- 4 Key Pillars

1. Architecture & Sustainable Design

2. Engineering Product Development

3. Engineering Systems & Design

4. Information Systems Technology & Design

- US$100m International Design Centre for

world-class research in design processes to

address issues such as engineering and design

for sustainable environment and the

developing world.

- Opened in 2012. Intake of 386 in 2015.

SINGAPORE UNIVERSITYOF TECHNOLOGYAND DESIGN

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- An industry-focused partnership

between polytechnics and reputable

overseas universities

- Poly – Foreign University tie-up to

offer degree programs:

- Allied Health & Nursing

- Design

- Digital Media

- Engineering & Applied Sciences

- Hospitality

- Each poly to house an SIT Building

- 1,500 full-time students per intake

- Applicable for all polys:

- Expansion into academic CET- Innovation fund (MOE)

SINGAPORE INSTITUTEOF TECHNOLOGY

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- The Technical University of Munich

(TUM) is the only German University

with campus outside Germany, through

GIST-TUM Asia

- MSc programs:

- 2002: Jointly with NUS and NTU in Industrial

Chemistry, Aeronautics, Microelectronics,

IC Design

- 2009: Independent TUM MSc in Transport

and Logistics

GERMAN INSTITUTEOF SCIENCE AND TECHNOLOGY-TUM(GIST-TUM) ASIA

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- Degree programs: Expansion under Singapore Institute of Technology to offer Electrical Engineering (2010)

- Research excellence: TUM-CREATE Centre on Electromobility in Megacities (2010)

- Industrial linkages: Partners German and other companies in Singapore

TEMASEKPOLYTECHNIC (TP)

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Temasek Polytechnic’s Applied

Food Science & Nutrition and,

Baking and Culinary Science

Diploma programmes boost

strong focus on nutritional

sciences, assessments, food

product development and

menu creation.

Dr Lee Chee Wee, DirectorSchool of Applied Sciences

Research Areas & Facilities

- Product Development of healthier foods & recipes

- Food Hygiene & Safety

- Nutrition R&D activities

- Traditional Chinese Medicine Research

- Glycemic Index Research

- Dedicated centres for TCM, GI and Clinical Nutrition R&D

Collaboration Examples

- Recipe development with the world’s largest snacks company

- Partner HPB on Glycemic Index research

- Partner SICS in undertaking clinical nutrition trials

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FOOD INNOVATION ANDRESOURCE CENTRE (FIRC)

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Provides consultancy services,

training & development and

lease of equipment

Partner faculties on-campus for

multi-disciplinary approach to

product and packaging

innovation

Situated in Singapore Polytechnic

Services and Facilities

Services

- Process, packaging and product development

- Training and Development

- Sensory and consumer evaluation studies

Facilities

- Pilot Plant

- Sensory booths

- A range of processing equipment from

various vendors

Collaboration Examples

New Product

Buckwheat Green Tea:Optimising buckwheat’s roasted-ness and green tea’s delicate taste

New Packaging

Singapore Sling:Made ready-to-drink by using novel ingredients and processing to achieve consistent quality

Process Optimisation

Lenas Pizza:Shortened preparation time with ready-to-use frozen dough while maintaining signature thin base

THANK YOUContact us for more information or to schedule anappointment.