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Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a regional problem in Montana

Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

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Page 1: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Selenium (Se)•Only nutrient whose level is

controlled by FDA•Has smallest optimal range• (difference between requirement and

toxicity)• Toxicity can be a regional problem in

Montana

Page 2: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Selenium (Se)• There are Se accumulating plants• Can be indicators of toxicity• Can result in acute toxicity – sudden

death•Astragalus species (locoweed)• Vetches• Some native range plants

Page 3: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Selenium (Se) Toxicity•Originally called Alkali disease• Chronic toxicity•Affects keratin of hair/hooves• Rough hair coat• “Bobbed” tail• Sloughed hooves•Affects adult animals

Page 4: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Se Deficiency• Se deficiencies that affect young

animals•Nutritional Muscular Dystrophy•White Muscle Disease•Affects ability to stand and nurse

Page 5: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Se Deficiency• In reproductive females• Retained placenta•Decreased fertility

Page 6: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Iodine (I)•Not high in feeds• Therefore we use Iodized salt• (even for humans)• Regional deficiency – Great Lakes,

Montana

Page 7: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Iodine Deficiency•At any age = Goiter• Enlargement of thyroid gland• Thyroxine contains Iodine• In reproductive females = stillbirths•Weak, hairless young

Page 8: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Mn Deficiency• Symptoms:• Lameness•Abnormal bone growth• Immune dysfunction

Page 9: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Mn Deficiency• In reproductive females:•Delayed estrus• Reduced ovulation• Embryonic mortality•Decreased fertility

Page 10: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Cobalt (Co)• Required for rumen microbes to

synthesize Vitamin B12

• Part of Vit. B12’s chemical structure

Page 11: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Cobalt (Co)•Deficiency regional grazing

Page 12: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Wasting Disease (Co deficiency)• First discovered in Australia•Australia – extreme emaciation• Because Vit B12 important in energy

metabolism

Page 13: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Wasting Disease (Co deficiency)• To cure:• Cobalt must be provided to rumen• Injection of Co won’t work • (because Co needed in rumen to

synthesize Vit. B12)• Injection of Vitamin B12 will work

Page 14: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals• Chelated•Attached to amino acids

• Proteinated•Attached to peptides

• Complexed•Attached to other organic

compounds

Page 15: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals•Usually Zn, Cu, Mn, & Co are included

in organic form•Hypothesis: Increased availability

Page 16: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

Example feed tag containing organic minerals

Page 17: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals•Are they effective?• Conflicting research results• Positive results with animals that are:•High producing• Stressed• Immune-compromised

Page 18: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals•Organic forms are more expensive

than sulfates, chlorides, etc.• Therefore, they must be cost effective

Page 19: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals• Recommendation for organic mineral

use:• If high S, Fe and/or Mo

(antagonists)

Page 20: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals• Recommendation• If problems occur such as:• Calf/lamb scours• Increased reproductive failure• Change in hair color• Increased foot rot• Increased respiratory infections

Page 21: Selenium (Se) Only nutrient whose level is controlled by FDA Has smallest optimal range (difference between requirement and toxicity) Toxicity can be a

“Organic” Minerals•Due to cost, recommendation is:• 70% inorganic + 30% organic• Supplementation during strategic

(stressful) times:• Cows – prior to calving through

breeding• Ewes – prior to lambing, during

breeding• Calves/lambs – prior to weaning