HOW???

RED BIOTECHNOLOGYJEFF NATHAN ESTO SALE IV - LASER

WHAT IS MEDICAL / REDBIOTECHNOLOGY?

is the use of living cells and cell materials to research and produce pharmaceutical and diagnostic products that help treat and prevent human diseases.

Biopharmaceuticals - drugs that are manufactured using biotechnological methods.

CLASSIFICATION OF BIOPHARMACEUTICALS

Blood factors Hormones Haematopoietic growth factors Vaccines Monoclonal antibodies (Various) Other products

PRODUCTS OF RED BIOTECH

HUMAN INSULIN (HUMULIN) Manufactured by Genentech for

diabetic patients in 1982 the world’s first biotechnologically

manufactured medicine.

PRODUCTS OF RED BIOTECH

NEORECORMON A Roche Group genetically engineered medicine

that is used to treat anemia. contains the active ingredient epoetin beta,

which is also known as recombinant human erythropoietin, a hormone which stimulates the production of red blood cells in the bone marrow and spleen.

PRODUCTS OF RED BIOTECH

GARDASIL the only human papillomavirus (HPV) vaccine

that helps protect against 4 types of HPV. helps protect against 2 types of HPV that cause

about 75% of cervical cancer cases helps protect against 90% of genital warts cases.

PRODUCTS OF RED BIOTECHARTIFICIAL BLOOD Cell-free solutions containing molecules that can

bind and transport oxygen like hemoglobin Benefits

Disease-free alternative to real blood Constant supply Universal donor type

Disadvantages Cannot perform all the functions of a red blood cell-only

oxygen delivery Edward Cullen wants this blood.

PRODUCTS OF RED BIOTECH

Xenotransplantation Transplanting organs from one species into

another May someday become an alternative to human-to-

human transplantation 1984 baboon heart transplanted into a 12-year-old

human girl, and the Girl died after 3 weeks as a result of organ rejection

HOW DID THEY DO IT?

UPSTREAM PROCESSING proteins are produced by cells genetically

engineered to contain the human gene which will express the protein of interest.

DOWNSTREAM PROCESSING the produced proteins are isolated and purified,

formulated (meaning excipients are added to the protein), filter sterilized, filled aseptically, lyophilized, sealed, inspected and labeled.

HOW DID THEY DO IT?

HOW DID THEY DO IT?

PHARMACOGENOMICS a science that examines the inherited variations

in genes that dictate drug response and explores the ways these variations can be used to predict whether a patient will have a good response to a drug, a bad response to a drug, or no response at all.

PHARMACOGENOMICS

BIOCHIPS

miniaturised analytical tools that are used in diagnostics.

They enable the rapid analysis of a patient’s individual genetic make-up, enable the early diagnosis of diseases

TRIVIAS

In 1978, the first test-tube baby, Louise Brown was born in United Kingdom

In 1976, the swine flu vaccine caused more deaths and illness than the disease it was intended to prevent.

In 2012, the movie Thrae will be shown in theaters nationwide

THAT’S ALL,THANKYOU