Practical Pathology 4

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    PRACTICAL PATHOLOGY 4: CANCER COLON

    A)Jars:-

    Organ: Part of the large intestine

    Description:

    A large submucous tumour is bulging into the lumen of the intestine. The tumour: Is ovoid in shape Has smooth external surface Has a short narrow pedicle

    Cut surface is whorly in appearance

    Diagnosis: Myoma

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    Organ: Part of the large intestine

    Description:

    The ileocaecal junction is infiltrated by a large non-encapsulated grayishwhite, ill defined hard mass with focal translucent areas of jelly like

    material

    The tumour has invaded the wall of the caecum and sent similar tumourdeposits to the draining lymph nodes

    Diagnosis: Mucoid carcinoma of the colon

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    Organ : Part of the large intestine

    Description:

    Segment of the left colon shows an ill defined grayish white non-encapsulated tumour invading the wall of the colon circumferentially

    causing its constriction in a purse string like pattern.

    The tumour is hard in consistencyDiagnosis: Annular carcinoma of the left colon

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    Organ: Part of the large intestine

    Description:

    A large ovoid ulcerative mass is seen. The ulcer is

    Solitary Size: large Outline: Irregular Edge: raised and everted Floor: covered by blood clots and necrotic debris Base: hard, fixed and indurated

    Diagnosis: Ulcerative carcinoma of rectum

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    Organ: Part of the large intestine

    Description:

    A solitary, large, fungating polypoidal mass projecting into the lumen Colour of the mass: grayish white Consistency: firm

    Diagnosis: fungating carcinoma of the lower rectum.

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    B) Slides :-

    Adenocarcinoma, colon:

    Part of the colonic wall showing:

    Focal mucosal ulceration The submucosa and muscle coat are by infiltrated by carcinomatous cells

    arranged in glandular formations of different sizes and shapes

    The tumour cells are mostly columnar and show large hyperchromaticnuclei

    Mitotic figures are detected

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

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    MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

    ACE 2013/14

    Mucoid carcinoma, colon

    Part of the colonic wall showing.

    Focal mucosal ulceration Infiltration of the submucosa as well as part of the muscuosa by clusters

    and masses as well as occasional tubular formations of carcinomatous cells

    showing large hyperchromatic nuclei and scant cytoplasm.

    Mitotic figures are detected The tumour cells area seen within abundant mucous pools.

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