K.KARTHIK,

5070,

VBM.

MASTITIS• Inflammation of udder

Causative agents include• Bacteria• Fungi• Algae,etc.,

INTRODUCTION• Associated with over 26 species

• Candida spp., Aspergillus spp., Trichosporon spp., Cryptococcus spp., Saccharomyces spp., Penicillium spp., etc. (CARTER, 1995).

• Fungi as the cause of mastitis -Rolle (1934), isolated yeasts from five cows being fed on brewery by-products.

• Candida is the most common species isolated (Radostitis, 1995).

• Yeasts and Actinomycetes seem to be best adapted to growth in the ducts and acini of the udder

yeast yeast

actinomycetes

SYMPTOMS• Gradual development of swelling (Pounden et

al .,1952)

• Loss of appetite and a rise in temperature but absence of toxaemia (Simon et al.,1953)

• Swelling in all four quarters within 12 hours (Galli ,1954)

MILK• Greyish or yellowish floccules have been

reported – yeasts (Andersen & Jorgensen, 1949)

• A mucilaginous secretion - cryptococcal infection

MASTITIS - GOAT

Markedly enlarged (about 2 times) right (R) infected

Markedly swollen and enlarged right udder half (R) goat 24 hrs after infection with Candida albicans.

HISTOPATHOLOGY• Marked neutrophil infiltration

• Phagocytosed spores within the macrophages

• Extensive fibrosis in the interlobular septa dividing the lobules

• Pseudohyphae and budding yeasts of C. albicans mixed with purulent exudate in the lumina of acini

Geotrichum candidum• Keratinophilic yeast

• Extremely rare (mishra and panda, 1986;seddek, 1997; krzyzanowski and sielicka, 1996).

• Any injury to teat sphinctures, or unhygienic milking, can lead to its entry.

• Milk-watery with thick flakes, and slightly blood tinged

• Microscopically the fungal mycelia were septate and some were fragmented into rectangular arthrospores

• Sensitive only to amphotericin-B.

DIAGNOSIS• Strip cup test – change in colour,consistency

• Isolation and identification

aspergillus candida

cont

cryptococcus penicillum

CLINICAL IMPORTANCE• Administration of antibiotics may aggravate

fungal mastitis as Candida spp. utilize penicillin and tetracyclines as a source of nitrogen (Meek, 1981).

candida

antibiotic

TREATMENTAntifungal drugs like:-

• Nystatin , natamycin – for yeast mastitis

• Amphotericin B – geotrichum