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Macular Degeneration Treatment
Ranibizumab (Lucentis) Pegaptanib (Macugen)
Antibody fragment that binds to VEGF-A isoforms Oligonucleotide that binds to VEGF-165
Loading phase of one injection per month for 3 consecutive months, followed by a maintenance phase
Intravitreal injection into the affected eye administered once every 6 weeks (9 injections per year)
Cost per injection = £761.20
2-year cost up to £18,300 assuming 12 injections in the first year and another 12 in the second year
Cost per injection = £514.00
2-year cost up to £9,300 assuming 9 injections in the first year and another 9 in the second year
TA 155
Ranibizumab and pegaptanib for the treatment of age-related macular degeneration Full url- http://publications.nice.org.uk/ranibizumab-and-pegaptanib-for-the-treatment-of-age-related-macular-degeneration-ta155