JACIE update

United Kingdom

Overview

• 60 first-time applications– UK second highest number of applications (19% of all

applications to JACIE)

• 87 inspections performed – Highest of all countries – incl. first-time and reaccreditation

• Highest number of accreditations awarded at least once - 54– Next country - 30

Take-up

Applications by centres reporting transplant to survey

Total UK

% total qualified* 39% 74%

% qualified auto only 15% 56%

% qualified allo 54% 94%

* Qualified – auto ≥5 tx; allo ≥10 tx

Based on 2011 EBMT Activity Survey

Also:•Saudi Arabia •South Africa

  90-100%  80-89%  70-79%  60-69%  50-59%  40-49%  30-39%  20-29%  10-29%  0-9%

Countries colour-coded according to percentage of reporting centres that have applied for accreditation* Survey data provided courtesy of Helen Baldomero, EBMT Activity Survey

Take-up of centres reporting transplants to 2011 EBMT Activity Survey

Take-up of centres reporting allogeneic transplants to 2011 EBMT Activity Survey

Also:•Saudi Arabia •South Africa

  90-100%  80-89%  70-79%  60-69%  50-59%  40-49%  30-39%  20-29%  10-29%  0-9%

Countries colour-coded according to percentage of reporting centres that have applied for accreditation* Survey data provided courtesy of Helen Baldomero, EBMT Activity Survey

Stoke Mandeville Hospital AylesburyQueen Elizabeth Hospital BirminghamBlackpool Teaching Hospitals NHS Foundation Trust BlackpoolThe Royal Bournemouth and Christchurch Foundation NHS Trust BournemouthAddenbrookes Hospital CambridgeDudley Group of Hospitals NHS Trust DudleyWestern General Hospital & Scottish National Blood Transfusion Service (SNBTS)

Edinburgh

Royal Devon & Exeter NHS Foundation Trust Hospital ExeterNHS Greater Glasgow & Clyde, Haemopoietic Stem Cell Transplantation Services

Glasgow

SNBTS, Glasgow GlasgowRoyal Hospital for Sick Children GlasgowHull and East Yorkshire Hospitals NHS Trust Kingston upon HullNHS Blood and Transplant Centre LiverpoolRoyal Free Hospital NHS Trust LondonImperial College Healthcare NHS Trust (Hammersmith Hospital) LondonSt. George's Healthcare NHS Trust LondonUCLH NHS Foundation Trust LondonBart's & The London NHS Trust LondonTrustees of the London Clinic Ltd London

Accredited centres 1/2•Valid as of 6 Nov 2013

Imperial College Healthcare NHS Trust (Hammersmith Hospital) LondonRoyal Manchester Children's Hospital (CMFT) ManchesterCentral Manchester University Hospitals NHS Foundation Trust (CMFT) ManchesterCentral Manchester University Hospitals NHS Foundation Trust (CMFT) ManchesterNorfolk and Norwich University Hospital NHS Foundation Trust (NNUH) NorwichNHSBT Oxford & Lymphoma Group OxfordNational Health Services Blood and Transplant (NHSBT) OxfordOxford Radcliffe Hospitals NHS Trust OxfordWillow Bond Ltd PlymouthPlymouth Hospitals NHS Trust, Royal Cornwall Hospitals NHS Trust & South Devon Healthcare NHS Foundation Trust

Plymouth

Poole Hospital NHS Foundation Trust PooleNational Blood Service SheffieldSheffield Children's NHS Foundation Trust SheffieldNHS Blood and Transplant SouthamptonUniversity Hospital Southampton NHS Foundation Trust SouthamptonUniversity Hospital of North Staffordshire Stoke-On-TrentThe Great Western Hospitals Foundation Trust Swindon

Accredited centres 2/2•Valid as of 6 Nov 2013

In reaccreditation process

•Valid as of 6 Nov 2013

Institution Name City

The Christie NHS Foundation Trust Manchester

Filton Blood Centre Bristol

Sheffield Teaching Hospitals NHS Foundation Trust Sheffield

King’s College Hospital NHS Foundation Trust London

Heart of England NHS Foundation Trust Birmingham

The Royal Free London NHS Foundation Trust London

Yorkshire Blood and Bone Marrow Transplant Centre Leeds

The Royal Marsden NHS Foundation Trust London

University Hospitals Leicester Leicester

NHSBT Birmingham

Bristol Royal Hospital for Children & Bristol Haematology/Oncology Centre Bristol

Nottingham University Hospitals NHS Trust Nottingham

South Warwickshire Foundation Trust Warwick

King’s College Hospital NHS Foundation Trust London

University Hospital Coventry Coventry

Centres reporting transplants in 2011 that have not applied

Institution Name City 1st Allo 1st AutoIpswich Hospital Ipswich 0 8Belfast City Hospital Trust Belfast 9 33Royal Victoria Infirmary Newcastle upon Tyne 80 83The Royal Infirmary Aberdeen 2 20Cheltenham General Hospital Cheltenham 0 15Parkside Hospital London 0 2Singleton Hospital, Sketty Swansea 0 19Royal United Hospital Bath 0 10Taunton and Somerset Hospital Somerset 0 14Ninewells Hospital Dundee 0 9Ysbyty Gwynedd Bangor 0 11Salisbury NHS Foundation Trust Salisbury 0 4Alder Hay Liverpool 5 2The Birmingham Children's Hospital Birmingham 24 16

Text in red indicates activity below minimum requirements

Inspectors

• Total 39– Clinical 12– Clinical / Collection 8– Collection 4– Processing 8– Clinical / Collection / Proc. 2

Registered inspectors 1/2Name Surname Hospital CityMichael Alcorn Haematology Department, GlasgowMichael Quinn Belfast City Hospital BelfastVictoria Potter Kings College Hospital LondonMatthew Smith St Bartholomew's Hospital LondonNorbert Blesing Dept of Haematology SwindonCharles Crawley Blood and Marrow Transplantation Unit CambridgeChristopher Dalley St. Georges Hospital LondonBrenda Gibson Royal Hospital for Sick Children GlasgowMike Hamon Plymouth Hospitals NHS Trust PlymouthDaniel Hollyman NHSBT Birgminham Birmingham

Sally KinseyBlood and Bone Marrow Transplant Centre Leeds

Sandra LoaizaHammersmith Hospital, Imperial College Healthcare NHS Trust London

Mark Lowdell Laboratory of Cellular Therapeutics LondonLynn Manson Department of Transfusion Medicine EdinburghLouise McNamara Royal Marsden Hospital London

Registered inspectors 2/2Kim Orchard Haematology, Oncology, & Paediatrics SouthamptonJiri Pavlu Hammersmith Hospital London

Rachel PawsonNHSBT Oxford Centre, John Radcliffe Hospital Oxford

Mike Potter Department of Hematology LondonChristine Protheroe The Dudley Group of Hospitals NHS Trust DudleyDeborah Richardson University Hospital Southampton SouthamptonTuula Rintala Dept of Clinical Haem London

Claudius RudinRoyal Devon & Exeter Hospital

ExeterNigel Russell Nottingham City Hospital NottinghamHamdi Sati Singleton Hospital SwanseaMike Scott Department of Clinical Haematology CambridgeMaryam Sekhavat Royal Free Hospital LondonPaneesha Shankara Birmingham Heartlands Hospital BirminghamGraeme Smith Dept of Haematology Leeds

Jon SmytheNHS Blood and Transplant Laboratory, Oxford Oxford

John Snowden Royal Hallamshire Hospital Sheffield

Paul VeysGreat Ormond Street Hospital for Children NHS Trust London

Claire Wiggins Steve Mills Lab Southampton

Inspector Training

• Next course

• Barcelona, October 2-3, 2014

• Contact eoin.mcgrath@ebmt.org

14

JACIE & Health AuthoritiesRegulations• Belgium• NEW Croatia• France • Switzerland• Italy • The Netherlands

Guidelines• United Kingdom

– Manual for Cancer Services Haemato-oncology Cancer Measures Version 1.0 (2013)– Improving Outcomes in Children and Young People with Cancer (2005)– Improving Outcomes in Haematological Cancers (2003)– The Future of Unrelated Donor Stem Cell Transplantation in the UK. A Report from the UK

Stem Cell Strategic Forum (July 2010). NHSBT– JACIE cited in Specialised Services National Definitions Set (3rd edition) SSNDS Definition

No.2, Specialised Services for Blood and Marrow Transplantation (all ages)– Welsh Health Specialised Services (WHSSC) Blood and Marrow Transplantation

Commissioning Policy

www.jacie.org/about/national-regulations

6th edition Standards

2013• June - Kick-off• Aug-Dec - Sub-committee telecons2014• Feb - Meeting of Committees at Tandem

Meeting • Apr-Jun - Public consultation• Oct - approve final version2015• Mar – publish