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Introduction to DNA Transcription and Translation. The Overview. Makin' Proteins. So proteins are determined by the chain of amino acids that make them up. But how do our protein makers know which amino acids to add?. - PowerPoint PPT Presentation
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So proteins are determined by the chain of amino acids that make them up
But how do our protein makers know which amino acids to add?
We Shall Start the Process of Transcribing the DNA (Genetic Blue Print)
1. Open up and Read the DNA strand
2. Make a copy of the DNA sequence in RNA that we will call Messenger RNA (mRNA)
3. Send the copy out of the Nucleus to be read off of, so that proteins can be made
Let’s make a Template People! We need to copy DNA, but only copy it – how about a messenger version called mRNA
When mRNA meets tRNA, the message is written, or TRANSLATED! The result is amino acid linking into protein!
Note how the tRNA to the left leaves and donates the amino acid to the neighbor on the right
On mRNA, there are words, composed of 3 letters
3 Letters = 1 Word (a CODON)
Each word = an AMINO ACID
DNA Sentences are Wonderful – okay, I’m lying,
but they’re on the test
Alanine
Valine
Cysteine
Arginine
Glycine
Proline
Amino AcidGCA
GUA
UGU
AGA
GGA
CCA
CODON
STOP construction!UGA
The Ribosome (the Hamburger)
tRNA (the Amino Acid delivery man)
• The ribosome is the site of protein synthesis, one amino acid at a time.
• tRNA is the evil little delivery system, which happens to be made of RNA
mRNA copied off a DNA strand pops out of the nucleus!
tRNA delivering the Amino Acid to the matching mRNA destination
Amino Acid chain growing
And this happens very quickly all at once...And this happens very quickly all at once...
mRNA
Amino Acids to protein