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Name of drug Indications Dosage Administration Ultraxime oral susp 100 mg_5 mL Treatment of in fections caused by gm +ve & gm -ve mic roorganis ms inc lud ing bronchitis, bronchiectasis w/ infection, secondary inf ections of chroni c resp tract disea ses, pneumonia !yelonephritis, cy st itis, cystourethritis, unco mplic ated gonorr hea "holecystit is, cholangitis, scarlet fever , otit is media, sinusitis, tonsilitis, pharyngitis, typhoid fever Childn Total dai ly dos e# $ mg/%g body wt as a single dose or in e'ually divide d doses ( hrly e)cept for *TI given as once daily dose Susp  Adult & childn >12 yr   m once daily or ( m ( hrlyChildn 7-12 yr  (-( m once daily or - . m ( hrly 3-6 yr  -( m once daily or - m ( hr ly 1-2 yr   - m once dai ly or ( - m ( hrly Drops Childn 6  mt h-2 yr    - m once daily or (- m ( hrly Duration of treatment# .-(0 days Infect ions due to Streptococcus  pyogenes  At least ( days Typhoid fever  Childn Total daily dose# (- mg/%g body wt as a single dose or in e'ually di vi ded doses ( hrly for .-(0 days 1a)# 0 mg/day 2hould be ta%en with food "ontraindications 2pecial !recautions  Adverse Drug 3eact ions Drug Interactions 4ypersensi ti vity to other  cephalosporins or  penicillins  Allergy to any drug "onsider Clostridium difficile-ass ociat ed diarr hea & col it is in pa tie nt s w/ diarrh ea 4ist ory of coli tis, 5I malab sorpt ion 1oni tor prothrombin time in patients w/ renal or hepatic impairment, poor nutritional st at e, pati ents receiving pr otract ed antimi cr obial therapy & previously stabi li6ed on antic oagul ant thera py Disc ontin ue use if sei6ures occur Avoid long- term or repeated use 7alse +ve reaction in nitroprusside test, "oombs8 test, "linitest, 9enedict8s & 7ehling8s soln !regnancy & lact at ion "hildn :; mth "<2 & 5I disorders hyper sens itiv ity reactions hepatic, renal & hematologic ef fect s Dysuri a, py uri a, genita l pruritus, vag ini tis , vag candidiasis hyperbilirubinemia increased ser um amy lase conc =iew AD3 1onitoring 7orm "arbama6epine, chloramphenicol, nifedipine, pr ob enec id, sa li cy lates >as pir in? , war far in & oth er anticoagulants 1I12 "lass

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7/24/2019 Drugs study.docx

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Name of drug Indications Dosage Administration

Ultraxime oral susp

100 mg_5 mL

Treatment of infections

caused by gm +ve & gm -ve

microorganisms including

bronchitis, bronchiectasis w/

infection, secondary

infections of chronic resp

tract diseases, pneumonia

!yelonephritis, cystitis,

cystourethritis,

uncomplicated gonorrhea

"holecystitis, cholangitis,

scarlet fever, otitis media,

sinusitis, tonsilitis,

pharyngitis, typhoid fever

Childn Total daily dose# $

mg/%g body wt as a single

dose or in e'ually divided

doses ( hrly e)cept for *TI

given as once daily

dose Susp  Adult & childn

>12 yr   m once daily or 

( m ( hrlyChildn 7-12 

yr  (-( m once daily or -

. m ( hrly 3-6 yr  -(

m once daily or - m

( hrly 1-2 yr  - m

once daily or (- m

( hrly Drops Childn 6 

mth-2 yr  - m once

daily or (- m ( hrly

Duration of treatment# .-(0

days Infections due

to Streptococcus

 pyogenes At least (

days Typhoid

fever  Childn Total daily

dose# (- mg/%g body wt

as a single dose or in

e'ually divided doses (

hrly for .-(0 days 1a)# 0

mg/day

2hould be ta%en with food

"ontraindications

2pecial !recautions  Adverse Drug 3eactions Drug Interactions

4ypersensitivity to other 

cephalosporins or  

penicillins

 Allergy to any drug

"onsider Clostridium

difficile-associated diarrhea

& colitis in patients w/diarrhea 4istory of colitis,

5I malabsorption 1onitor 

prothrombin time in patients

w/ renal or hepatic

impairment, poor nutritional

state, patients receiving

protracted antimicrobial

therapy & previously

stabili6ed on anticoagulant

therapy Discontinue use if 

sei6ures occur Avoid long-

term or repeated use 7alse

+ve reaction in nitroprusside

test, "oombs8 test, "linitest,

9enedict8s & 7ehling8s soln

!regnancy & lactation

"hildn :; mth

"<2 & 5I disorders

hypersensitivity reactions

hepatic, renal & hematologic

effects Dysuria, pyuria,genital pruritus, vaginitis,

vag candidiasis

hyperbilirubinemia

increased serum amylase

conc

=iew  AD3 1onitoring 7orm

"arbama6epine,

chloramphenicol, nifedipine,

probenecid, salicylates

>aspirin?, warfarin & other anticoagulants

1I12 "lass

7/24/2019 Drugs study.docx

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"ephalosporins