Estrogen Dominance S/Sx:

-swelling of

breasts

-depression

-loss of sexual

drive

-dysmenorrhea

Proliferation of cells in

the uterus

Development of uterine fibroid

Interference in the vascular supply

Degeneration in the

interior part of the fibroid

Overgrowth of the endometrial lining

Treatment:

-GnRH

agonist

-Tamoxifen

-SERM

Diagnostic Tests:

-Pelvic examination

-Ultrasonography

Sx:

Hypermenorrhea

If treated with

radiation

If not treated

29

Predisposing Factors:

Age h. High-fat Diet

Gender i. Obesity

Race j. Family history

Lifestyle k. Anxiety

Early Menarche

a. Nulliparity

b. Use of oral contraceptives

ETIOLOGY:

Unknown

Precipitating Factors:

a. Hormone Replacement

Therapy (Premarin)

Anovulation

b. Luteal Insuffiency