Department of Pharmacognosy Courses Specificationsdeltauniv.edu.eg/new/pharmacy/wp-content/uploads/Pharmacognosy-Specs... · Course Contents ILOs K&U IS P&PS G&TS 1. Plant cell structure

Department of Pharmacognosy

Courses Specifications

2017-2018

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Contents

Botany ................................................................................................................... 2

Pharmacognosy-1 ................................................................................................ 7

Pharmacognosy-2 .............................................................................................. 14

Phytochemistry-1 ............................................................................................... 21

Phytochemistry-2 ............................................................................................... 27

Phytotherapy ...................................................................................................... 33

Herbal medicine ................................................................................................. 39

Marine Drugs ..................................................................................................... 43

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Delta University for Science and Technology

Quality Assurance Center

Course Specifications

1. Basic Information:

Course Title: Botany

Course Code: PG 111

Program on which the course is given: B. Pharm.

Department offering the course: Pharmacognosy

Academic year/ level: Fall Semester 2017/2018 Level one

Prerequisite: None

Credit hours: Lecture: 2 Practical: 1 Total: 3

2. Course Aims:

Providing the student with basic knowledge of the field of botany, and the skills necessary for

further studies in the field of medicinal plants, pharmacognosy, phytochemistry and

phytotherapy.

3. Intended Learning Outcomes (ILOs):

a. Knowledge and understanding:

At the end of this course, student should be able to:

A1

a1. Describe the characters of plant cell and different tissues and organs and list the

differences between their structures.

a2. Describe different morphological and anatomical structures found in each plant

organ in different stages of the plant life.

a3. Illustrate how the morphological and anatomical structure can be modified

according to the habitat and function.

a4. Recognize the importance of taxonomy in identification and classification of

medicinal plants.

a5. Outline the concepts of plant primary and secondary metabolites in relation to

plant cell physiology.

b. Intellectual Skills:


B13

b1. Distinguish different plant cell types and identify different plant tissues and

organs based on anatomical characters.

b2. Write a full scheme for description of different plant organs.

b3. Classify plant samples according to their morphological and anatomical

characters.

B5 b4 Utilize appropriate methods for identification of various plant primary and

secondary metabolites.

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c. Professional and Practical Skills:


C2 c1. Handle and dispose chemicals safely

C8 c2. Manipulate pharmaceutical instruments and equipment safely and efficiently

(microscopes, pipettes, slides and cover slips, ………etc.)

C11

c3. Develop the required skills to prepare histological tissues of the plant.

c4. Apply acquired information to describe morphological and anatomical

characters of real life samples.

c5. Integrate different morphological and anatomical aspects to conclude a

scientific classification of plants.

d. General and Transferable Skills:


D3 d1. Work effectively as a part of a team and independently to perform the

required tasks.

D9 d2. Acquire effective time-management skills.

4. Contents:

4.1.Lectures:

Study

week Topics

No. of

Credit Hours

1. Plant cell structure and function + Ergastic cell contents 2

2. plant tissues: Dermal, ground vascular and secretory tissues 2

3. Anatomy of primary plant organs. 2

4. Anatomy of primary plant organs + Anatomy of secondary

plant organs. + Quiz 1 2

5. Habitat of plant and introduction to morphology of leaves 2

6. Morphology of leaves 2

7. Morphology of stems 2

8. Quiz 2

9. Morphology of roots 2

10. Morphology of flowers 2

11. Types of placentation and types of inflorescences 2

12. Introduction to plant Taxonomy 2

13. Introduction to plant Taxonomy and physiology 2

14. Final Exam

Total:

2 credit hours 15.

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4.2.Practical:

Study

week Topics

No. of

Credit Hours

1. Plant cell structure and function + Ergastic cell contents 1

2. plant tissues: Dermal, ground vascular and secretory tissues 1

3. Anatomy of primary plant organs 1

4. Anatomy of primary plant organs + Anatomy of secondary

plant organs. + Quiz 1 1

5. Introduction to morphology of leaves 1

6. Morphology of leaves 1

7. Morphology of stems 1

8. Theoretical Quiz 2

9. Morphology of roots 1

10. Morphology of flowers + Types of placentation and types of

inflorescences 1

11. Qualitative identification of plant primary and secondary

metabolites 1

12. Revision 1

13. Practical Exam 1

14. Final Exam

Total:

1 credit hour 15.

5. Teaching and Learning Methods:

5.1. Lectures

5.2. Practical work

5.3. Homework assignments

5.4. Brain storming

5.5. Learning management systems (Moodle)

6. Student Assessment Methods:

6.1. Assessment methods:

1. Written exam to assess knowledge, understanding, intellectual and professional

skills.

2. Practical exam to assess professional and practical skills.

3. Course work to assess knowledge, understanding, intellectual skills, general &

transferable skills.

4. Oral exam to assess knowledge, understanding, intellectual skills, general skills

and confidence.

5. Quizzes to assess knowledge, understanding and intellectual skills.

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6.2. Assessment schedule:

Assessment 1 Quiz 1 4th week


Assessment 3 Assignment/activity (homework questions) all over the term

Assessment 4 Practical exam 13th week

Assessment 5 Written exam 14th & 15th weeks

6.3.Weighing of Assessments:

1. Course work:

- Quiz 1 10

- Quiz 2 10

- Assignment/activity (homework questions) 5


3. Final-Term Exam 50

Total 100%

7. List of References:

No. Reference Type

1. Berg, L. "Introductory Botany, plants, people and the environment"

Thomson Higher Education, USA (2008). Textbook

2. Kar K.R., Misra M.N. and Kabi, T. "Text Book on Fundamentals of

Botany" New Delhi (2005). Textbook

8. Matrix of course contents versus ILOs:

8.1. Lectures:

Study

week Course Contents

ILOs

K&U IS P&PS G&TS

1. Plant cell structure and function +

Ergastic cell contents a1 b1 c4 --

2. plant tissues: Dermal, ground vascular

and secretory tissues a1 b1 c4 --

3. Anatomy of primary plant organs. a2 b1 c4 d1

4. Anatomy of primary plant organs +

Anatomy of secondary plant organs. a2 b1 c4 d1

5. Habitat of plant and animals and

introduction to morphology of leaves a3 b3 c4 d1

6. Morphology of leaves a2 b2 c4 d2

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7. Morphology of stems a2 b2 c4 d2

9. Morphology of roots a2 b2 c4 d2

10. Morphology of flowers a2 b2, b3 c4 d2

11. Types of placentation and types of

inflorescences a1 b2, b3 c4 d2

12. Introduction to plant Taxonomy a4 b3 c5 d2

13. Introduction to plant Taxonomy and

physiology a4,a5 b3 c5 d2

8.2. Practical:

Study


ILOs

K&U IS P&PS G&TS

1. Plant cell structure and function +

Ergastic cell contents a1 b1 c1-c4 --

2. plant tissues: Dermal, ground vascular

and secretory tissues a1 b1 , b3 c1-c4 --

3. Anatomy of primary plant organs a1, a2 b1, b3 c1-c4 d1, d2

4. Anatomy of primary plant organs +

Anatomy of secondary plant organs. a1, a2 b1, b3 c1-c4 d1

5. Introduction to morphology of leaves a2 b2, b3 c4 d1

6. Morphology of leaves a2 b2, b3 c4 d1

7. Morphology of stems a2 b2, b3 c4 d1

9. Morphology of roots a2 b2, b3 c4 d1, d2

10. Morphology of flowers + Types of

placentation and types of inflorescences a2 b2, b3 c4 d1, d2

11. Qualitative identification of plant

primary and secondary metabolites a5 b4 c1, c2 d1

12. Revision

Name Signature

Course Coordinator: Dr. Hatem Samir Abbas

Head of Department: Prof. Dr. Amani M. Marzouk

Approval Date 11/09/2017

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Course Title: Pharmacognosy-1

Course Code: PG 212

Program on which the course is given: B. Pharm


Academic year/ level: Spring Semester 2017/2018 Level two

Prerequisite: Botany PG 111

Credit hours: Lecture:2 Practical:1 Total:3

2. Course Aims:

Providing the student with an overview of the concept of pharmacognosy and the importance

of using drugs of natural origin for treating diseases and also the skills to identify, evaluate

and prescribe a crude drug for treating ailments and predict their toxicity, any health hazards

concerning their misuse and abuse and interactions if any.




A1.

a1 Discuss the pharmaceutical importance of leaves, flowers, barks and woods.

a2 List the different active constituents and their chemical classes for the

studied crude drugs and how to identify them chemically.

a3 Identify the different organs morphologically and under the microscope

A16. a4 Recognize the toxic profile of certain crude drugs and their interactions and

incompatibilities if any.

A22. a5 Recognize the proper medical and pharmaceutical terminology and

abbreviation in the relevant context.



B5.

b1 Conduct the information related to leaves, flowers, barks and woods.

b2 Design appropriate methods for identification of various crude drugs and

chemical compounds in them.

b3

Identify other drugs outside his main study, predict possible medicinal uses

based on identified constituents and determine their conformation with

pharmacopeial monographs.

B9. b4

Integrate acquired information to safely selecting crude drugs and avoiding

dangerous interactions.

B15. b5 Estimate health hazards of some drugs misuse.

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C2 c1 Handle and dispose chemicals safely

C8. c2 Manupilate pharmaceutical instruments and equipment safely and efficiently

(microscopes, pipettes, slides and cover slips, ………etc.)

C9. c3 Raise public awareness on rational use of herbal drugs and social health

hazards of drug abuse and misuse.

C11.

c4

Develop the practical skills of microscopically examining and identifying

different crude drugs in sections and powdered forms and testing chemically

for different active constituents

c5 Apply the acquired scientific knowledge to write full schemes and

monographs for other drugs under investigation.



D2. d1 Retrieve pharmaceutical and other drug information resources

D3. d2 Work effectively as a part of a team and independently to perform the required

tasks.

D6. d3 Develop the skills required for continued self- professional development and self-

learning

4. Contents:

4.1.Lectures:

Study

week Topics

No. of

Credit Hours

1. Introduction to pharmacognosy: History of treating with herbs

and important definitions in pharmacognosy. 2

2. Introduction to pharmacognosy: preparation of crude drugs

(collection, cultivation, drying, packaingandstoring). 2

3. Introduction to pharmacognosy: adultration of crude drugs

and outline of the chemistry of crude drugs. 2

4.

Introduction to leaves; Macro and micromorphological study

of examples for the medicinally used leaves: buchu and

Eucalyptus + Quiz 1

2

5. Macro and micro-morphological study of: rosemary,

peppermint and tea leaves. 2

6. solanaceous leaves( belladonna, Datura, Hyoscyamus), other

leaves as coca, Jaborandi and boldo. 2

7. Senna (Indian, Alexandrian and other allied leaves), Digitalis

purpurea and Digitalis lanata leaves 2

8. Quiz 2

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4.2. Practical:

Study

week Topics

No. of

Credit

Hours

1. Introduction to morphology and anatomy of leaves and Macro and

micromorphological study of Senna leaflets. 1

2. Macro and micromorphological study of Digitalis leaves 1

3. Macro and micromorphological study of solanaceousleaves

(Hyoscyamus, Datura and Belladona). 1

4. Macro and micromorphological study of solanaceous leaves

(Hyoscyamus, Datura and Belladona). 1

5. Macro and micromorphological study of Eucalyptus and Rosemary

leaves 1

6. Revision on leaves 1

7. Macro and micromorphological study of German Chamomile,

Pyrethrum and Calendula 1

8. Quiz 2

9. Macro and micromorphological study of Clove Buds and Hibisucs

flowers and marking of practical notes 1

10. Macro and micromorphological study of Cinnamon bark 1

11. Macro and micromorphological study of Quassia wood and Aleppo

galls 1

12. General chemical tests for the major classes of secondary

metabolites present in plants and general revision. 1


14. Final Exam

Total: 1

credit

hour 15.

9.

Introduction to flowers; Macro and micromorphological study

of examples for medicinally used flowers s: Pyrethrum,

German and Roman Chamomiles, Arnica, santonica,

2

10. Saffron, safflower and clove. 2

11.

Introduction to barks; Macro and micromorphological study

of examples for medicinally used barks: cinnamon, cassia and

canella barks.

2

12. Cinchona, cascarilla, frangula, and pomegranate barks. 2

13.

Introduction to woods; Macro and micromorphological study

of examples for medicinally used woods: Quassia, guaiacum,

sandal, logwood and juniper woods. Galls.

2

14. Final Exam

Total:

2 credit hours 15.

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5.1. Lectures

5.2. Practical sessions

5.3. Brain storming

5.4. Homework



6.1. Assessment methods:


skills.





and confidence.


6.2. Assessment schedule:



Assessment 3

Assignment (preparing a report about one

of the studied crude drugs and solving

online questions)

all over the term


Assessment 5 Oral exam 14th & 15th weeks


6.3. Weighing of Assessments:

1. Course work:

- Quiz 1 10

- Quiz 2 10

- Assignment/activity (preparing a report about

one of the studied crude drugs and solving

online questions)

5


3. Oral Exam 10


Total 100%

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No. Reference Type

1. Trease G.E. and Evans W.C., “Pharmacognosy”, William C.

Evans Edinburgh, London, New York, Philadelphia,

Sydney, Tornoto. 16th Ed. (2017).

Textbook

2. Fundamentals Pharmacognosy and Phytotherapy (by M.

Heinrich et al), Churchill Livingston publishing company

(2004).

Textbook

3. WHO monographs Periodical

4. www.nih.gov, www.herbalgram.com Website


8.1. Lectures:

Study


ILOs

K&U IS P&PS G&TS

1.

Introduction to pharmacognosy: History

of treating with herbs and important

definitions in pharmacognosy.

a1, a5 b1 c3 --

2.

Introduction to pharmacognosy:

preparation of crude drugs (collection,

cultivation, drying, packing and storing).

a1, a5 b1 c3 --

3.

Introduction to pharmacognosy:

adultration of crude drugs and outline of

the chemistry of crude drugs.

a1, a2, a5 b1 c3

d1, d3

4.

Introduction to leaves; Macro and

micromorphological study of examples

for the medicinally used leaves: buchu

and Eucalyptus + Quiz 1

a1-a4 b1-b4 c3 d1, d3

5. Macro and micro-morphological study of:

rosemary, peppermint and tea leaves. a1-a4 b1-b4 c3 d1, d3

6.

solanaceous leaves( belladonna, Datura,

Hyoscyamus), other leaves as coca,

Jaborandi and boldo.

a1-a5

b1-b5 c3

d1, d3

7.

Senna (Indian, Alexandrian and other

allied leaves), Digitalis purpurea and

Digitalis lanata leaves

a1-a5 b1-b5 c3

d1, d3

9.

Introduction to flowers; Macro and


for medicinally used flowers s:

Pyrethrum, German and Roman

Chamomiles, Arnica, santonica,

a1-a5 b1-b5 c3 d1, d3

http://www.nih.gov/

http://www.herbalgram.com/

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10. Saffron, safflower and clove. a1-a4 b1-b4 c3 d1, d3

11.

Introduction to barks; Macro and


for medicinally used barks: cinnamon,

cassia and canella barks.

a1-a4 b1-b4 c3 d1, d3

12. Cinchona, cascarilla, frangula, and

pomegranate barks. a1-a5 b1-b5 c3 d1, d3

13.

Introduction to woods; Macro and


for medicinally used woods: Quassia,

guaiacum, sandal, logwood and juniper

woods. Galls.

a1-a5 b1-b4 c3 d1, d3

8.2. Practical:

Study


ILOs

K&U IS P&PS G&TS

1.

Introduction to morphology and

anatomy of leaves and Macro and

micromorphological study of Senna

leaflets.

a1, a3 b2, b3 c1, c2,

c4,c5 d2, d3

2. Macro and micromorphological study

of Digitalis leaves a1, a3 b2, b3

c1, c2,

c4,c5 d2, d3

3.

Macro and micromorphological study

of solanaceous leaves (Hyoscyamus,

Datura and Belladona).

a1, a3 b2, b3 c1, c2,

c4,c5 d2, d3

4.


of solanaceous leaves (Hyoscyamus,

Datura and Belladona).

a1, a3 b2, b3 c1, c2,

c4,c5 d2, d3


of Eucalyptus and Rosemary leaves a1, a3 b2, b3

c1, c2,

c4,c5 d2, d3

6. Revision and marking of practical notes a1, a3 b2, b3 c1, c2,

c4,c5 d2, d3

7.


of German Chamomile, Pyrethrum and

Calendula

a1, a3 b2, b3 c1, c2,

c4,c5 d2, d3


of Clove Buds and Hibisucs flowers a1, a3 b2, b3

c1, c2,

c4,c5 d2, d3


of Cinnamon bark a2, a3 b2, b3

c1, c2,

c4,c5 d2, d3

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of Quassia wood and Aleppo galls a2, a3 b2, b3

c1, c2,

c4,c5 d2, d3

12.

General chemical tests for the major

classes of secondary metabolites

present in plants and general revision.

a2, a3 b2, b3 c1, c2,

c4,c5 d2, d3

Name Signature

Course Coordinator: Prof Dr. Amani Moukhtar Marzouk

Head of Department: Prof Dr. Amani Moukhtar Marzouk


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Course Title: Pharmacognosy-2

Course Code: PG 313



Academic year/ level: Fall Semester 2017/2018 Level three

Prerequisite: Pharmacognosy-1 (PG 212)


2. Course Aims:

Providing students with further knowledge related to drugs of natural origin, which are

reputed to have curative values or use in the pharmaceutical industry and the skills necessary

to select a crude drug for certain ailment, to identify the studied drugs, detect their

adulteration, their active constituents and any health hazards concerning their misuse, abuse

and interactions if any.




A1.

a1 Acquire knowledge about the pharmaceutical importance of seeds, fruits,

subterranean organs and unorganized drugs.

a2 List the different active constituents and their chemical classes for the

studied crude drugs and how to test for them chemically.

a3 Identify the different organs morphologically and under the microscope

A16. a4 Recognize the toxic profile of certain crude drugs and their interactions and

incompatibilities if any

A22. a5 Recognize the proper medical and pharmaceutical terminology and

abbreviation in the relevant context.



B5.

b1 Conduct the information related to seeds, fruits, subterranean organs and

unorganized drugs.

b2 Design appropriate methods for identification of various crude drugs and

chemical compounds in them.

b3

Identify other drugs outside the main study, predict possible medicinal uses

based on identified constituents and determine their conformation with

pharmacopeial monographs.

B9. b4 Integrate acquired information to safely selecting crude drugs and avoiding

dangerous interactions.

B15. b5 Estimate health hazards of some drugs misuse.

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C2. c1 Handle and dispose chemicals safely.

C8. c2 Manipulate pharmaceutical instruments and equipment safely and efficiently

(microscopes, pipettes, slides and cover slips, ………etc).

C9. c3 Raise public awareness on rational use of drugs and social health hazards of

drug abuse and misuse.

C11.

c4

Develop the practical skills of microscopically examining and identifying

different crude drugs in sections and powdered forms and testing chemically

for different active constituents.

c5 Apply the acquired scientific knowledge to write full schemes and monographs

for other drugs under investigation.



D2. d1 Retrieve pharmaceutical and other drug information resources

D3. d2 Work effectively as a part of a team and independently to perform the required

tasks.

D6. d3 Develop the skills required for continued self- professional development and self-

learning

4. Contents:

4.1.Lectures:

Study

week Topics

No. of

Credit

Hours

1. Introduction to seeds 2

2. Macro and micromorphological study of examples for the

medicinally used seeds : Linseed and Nux vomica 2


medicinally used seeds: cardamom and black and white mustards. 2

4.

Macro and micromorphological study of examples for the

medicinally used seeds: Strophanthus, colchicum seeds and

calabar beans + Quiz 1

2


medicinally used seeds: nutmeg and mace and fenugreek. 2

6.

Introduction to fruits; Macro and micromorphological study of

examples for the medicinally used fruits:Ammi vesnaga and Ammi

majus.

2

7. Macro and micromorphological study of the medicinally used

fruits: anise, and fennel, coriander, and star anise 2

8. Quiz 2

9.

Introduction to subterranean organs; Macro and micromorpho-

logical study of examples for medicinally used subterranean organs

as: Ginger and curcuma and rhubarb.

2

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4.2.Practical:

Study

week Topics

No. of

Credit

Hours


medicinally used seeds: cardamom and nutmeg 1


medicinally used seeds : Fenugreek and black mustard 1


medicinally used seeds : linseed 1


medicinally used seeds: nux vomica and marking of practical notes 1

5. Revision 1


medicinally used fruits : Anise and fennel 1


medicinally used fruits: corainder, Ammi visnaga and capsicum 1

8. Quiz 2

9.

Examples for Unorganized drugs: Gums, gelatin, aloes and resins

and resin combinations and general chemical tests for the major

classes of secondary metabolites present in plants.

1

10. Examples for medicinally used subterranean organs: ginger,

curcuma, rhubarb and liquorice 1

11. Revision on subterranean organs and marking of practical notes 1

12. Final revision (seeds, fruits, subterranean and unorganized drugs) 1


14. Final Exam

Total:

1 credit

hour 15.

10. Macro and micromorphological study of examples for medicinally

used subterranean organs as: liquorice, Ginseng and Rauwolfia. 2

11.

Macro and micromorphological study of examples for medicinally

used subterranean organs as: Krameria, Ipecac, senega and

galangal.

2

12. Unorganized drugs of medicinal uses such as: Gums, dried extracts

and latex 2

13. Unorganized drugs of medicinal uses such as: resins and resin

combinations 2

14. Final Exam

Total:

2 credit

hours 15.

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5.1. Lectures

5.2. Practical sessions

5.3. Brain storming

5.4. Homework



6.1.Assessment methods:

1. Written exam to assess knowledge, understanding, intellectual and professional skills.




4. Oral exam to assess knowledge, understanding, intellectual skills, general skills and

confidence.


6.2.Assessment schedule:



Assessment 3 Assignment (Search topic on unorganized drugs) all over the term





1. Course work:

- Quiz 1 10

- Quiz 2 10

- Assignment (Search topic on unorganized drugs) 5


3. Oral Exam 10


Total 100%

18 | P a g e


No. Reference type

1.

- Trease G.E. and Evans W.C., “Pharmacognosy”, William C. Evans

Edinburgh, London, New York, Philadelphia, Sydney, Tornoto.

16th Ed. (2017).

textbook

2. - Fundamentals Pharmacognosy and Phytotherapy (by M. Heinrich et

al), Churchill Livingston publishing company (2004). textbook

3. WHO monographs periodical

4. www.nih.gov, www.herbalgram.com website


8.1. Lectures:

Study


ILOs

K&U IS P&PS G&TS

1. Introduction to seeds a3 b1 c3

--

2.


of examples for the medicinally used

seeds : Linseed and Nux vomica

a1-a5 b1-b5 c3,c5 --

3.



seeds: cardamom, black and white

mustards.

a1-a5 b1-b4 c3,c5 d3

4.



seeds: Strophanthus, colchicum seeds

and calabar beans

a1-a5 b1-b5 c3,c5 d3

5.



seeds: nutmeg and mace and fenugreek.

a1-a5 b1-b4 c3,c5 d1,d3

6.

Introduction to fruits; Macro and


for the medicinally used fruits:Ammi

vesnaga and Ammi majus.

a1-a5 b2,b3-b5

c3,c5

d1,d3

7.


of the medicinally used fruits:

anise, and fennel, coriander, and star

anise

a1-a5 b2,b3-b5 c3,c5 d1,d3

9.

Introduction to subterranean organs;

Macro and micro-morphological study

of examples for medicinally used

subterranean organs as: Ginger and

curcuma and rhubarb.

a1-a5 b2,b3-b5 c3,c5 d1,d3

http://www.nih.gov/


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10.



subterranean organs as:liquorice,

Ginseng and Rauwolfia.

a1-a5 b2,b3-b5 c3,c5 d1,d3

11.



subterranean organs as: Krameria,

Ipecac, senega and galangal.

a1-a5 b1-b4 c3,c5 d1,d3

12. Unorganized drugs of medicinal uses

such as: Gums, dried extracts and latex a1,a2,a5 b1-b4 c3,c5 d1,d3

13. Unorganized drugs of medicinal uses

such as: resins and resin combinations a1,a2,a5 b1-b4 c3,c5 d1,d3

8.2. Practical:

Study


ILOs

K&U IS P&PS G&TS

1.



seeds: cardamom and nutmeg

a2, a3 b2 c1, c2,

c4, c5 d2, d3

2.



seeds : Fenugreek and black mustard

a2, a3 b2 c1, c2,

c4, c5 d2, d3

3.



seeds : linseed

a2, a3 b2 c1, c2,

c4, c5 d2, d3

4.



seeds: nux vomica and marking of

practical notes

a2, a3 b2 c1, c2,

c4, c5 d2, d3

5. Revision

6.



fruits : Anise and fennel

a2, a3 b2 c1, c2,

c4, c5 d2, d3

7.



fruits: corainder, Ammi visnaga and

capsicum

a2, a3 b2 c1, c2,

c4, c5 d2, d3

9.

Examples for Unorganized drugs:

Gums, gelatin, aloes and resins and

resin combinations and general

chemical tests for the major classes of

secondary metabolites present in plants.

a2, a3 b2 c1, c2,

c4, c5 d2, d3

21 | P a g e

10.

Examples for medicinally used

subterranean organs: ginger, curcuma,

rhubarb and liquorice

a2, a3 b2 c1, c2,

c4, c5 d2, d3

11. Revision on subterranean organs and

marking of practical notes a2, a3 b2

c1, c2,

c4, c5 d2, d3

12. Final revision (seeds, fruits,

subterranean and unorganized drugs) a2, a3 b2

c1, c2,

c4, c5 d2, d3

Name Signature

Course Coordinator: Prof. Dr. Amani M. Marzouk


Approval Date 11.9.2017

21 | P a g e





Course Title: Phytochemistry-1

Course Code: PG 321



Academic year/ level: Spring Semester 2017/2018 Level three

Prerequisite: Organic Chemistry-2 (PC 211)


2. Course Aims:

Providing the students with the knowledge of the chemistry of plant constituents and methods

of screening for active constituents, physico-chemical properties of different classes as

volatile oils, carbohydrates, bitter principles, resins, resin combinations and tannins. The

student will acquire adequate information about medicinally used representatives.




A1 a1 Identify the basic principles of the chemistry of natural products (such as

volatile oils, carbohydrates, bitter principles, resins, resin combinations and

tannins).

A2 a2 Recognize the physico-chemical properties of drugs (of natural origins) and

various substances used in preparation of medicines.

A3

a3 Understand principles of qualitative and quantitative determination of plant

active constituents (such as volatile oils, carbohydrates, Bitter principles, resins,

resin combinations and tannins).

a4 Define the basis of phytochemical screening of medicinal plants for their active

constituents.

A4 a5 Enumerate the theories of isolation, synthesis, purification, identification and

standardization of natural products.

A13 a6 Recall the chemical and pharmacological properties of drug including chemistry,

nomenclature, mechanisms of action, therapeutic uses, dosage and

contraindications, adverse drug reactions, and drug interactions.

22 | P a g e



B3 b1 Determine suitable methods of analysis of crude drugs as raw material.

B5

b2 Apply extraction processes to materials found in nature and resolving these

extracts into their pure constituents.

b3 Design appropriate methods for identification and standardization of various

chemical compounds (plant active constituents).

B9 b4 Select the proper drugs for various disease conditions.

B13. b5 Interpret experimental data based on relevant principles.




C4. c2 Select appropriate methods for extraction, isolation, synthesis, purification,

identification and standardization of active substances from different origins.

C8. c3 Manipulate pharmaceutical instruments and equipment safely and efficiently.

C9. c4 Raise public awareness on rational use of drugs and social health hazards of


C11. c5 Conduct experimental and research studies, including: presentation, analysis

and interpretation of the results.



D2 d1 Retrieve pharmaceutical, clinical and other drug information resources.

D3 d2 Work effectively as a part of a team to perform the required tasks.

D6 d3 Develop the skills required for continued self-professional development and

self-learning.

4. Contents:

4.1.Lectures:

Study

Week Topics

No. of

Credit

Hours

1. Carbohydrates, occurrence, significance, biosynthesis ,

classification and identification 2

2. Carbohydrates of medicinal and pharmaceutical importance: sugar

alcohols, monosaccharides and disaccharides 2

3. Homopolysaccharides 2

4. Heteropolysaccharides + Quiz 1 2

5. Bitter principles and other miscellaneous natural products:

Furanochromones, Furancoumarins 2

23 | P a g e

4.2.Practical:

Study

Week Topics

No. of

Credit Hours

1. Qualitative Tests of Monosaccharides 1

2. Qualitative Tests of Disaccharides 1

3. Qualitative Tests of Polysaccharides 1

4. Revision Carbohydrate 1

5. Carbohydrate practical exam 1

6. Assay of Clove oil 1

7. Assay of volatile oil containing peroxide 1

8. Quiz 2

9. Assay of volatile oil containing oxide 1

10. Assay of Bitter almond oil by Hydroxylamine method 1

11. Assay of volatile oil by bisulfite method 1

12. Revision 1


14. Final Exam

Total:

1 credit hour 15.


5.1 Lectures

5.2 Practical sessions

5.3 Brain storming

5.4 Learning management systems (Moodle)

6. Sesquiterpenes and lignans 2

7. Miscellaneous Natural products 2

8. Quiz 2

9. Essential oils, distribution and occurrence, physiological

significance and effects and side effects. 2

10. Methods of extraction of volatile oils, Chemistry of volatile oils,

classification and biogenesis 2

11. Terpene hydrocarbons, alcohols and esters. 2

12. Terpene aldehydes, ketones, and phenols. 2

13. Oxides, peroxides and miscellaneous. 2

14. Final Exam

Total:

2 credit

hours 15.

24 | P a g e




skills.





and confidence.





Assessment 3 Assignment (Training questions) all over the term





1. Course work:

- Quiz 1 10

- Quiz 2 10

- Assignment/activity (Training questions) 5


3. Oral Exam 10


Total 100%


No. Reference Type

1. Text book of Pharmacognosy and Phytochemistry. Biren Shah.

Elsevier, India. 2nd Edition (2013) textbook

2.

Trease G.E and Evans W.C.,''Pharmaconosy'', William C. Evans.

Edinburgh, London, new york, Philadelphia, Sydney, Toronto , 16th

Ed., (2017)

textbook

3.

Phytochmistry

Natural products research

Chromatographia

Phytochemical analysis

Periodicals

25 | P a g e


8.1. Lectures:

Study


ILOs

K&U IS P&PS G&TS

1.

Carbohydrates, occurrence,

significance, biosynthesis ,

classification and identification

a1, a3-a6 b1- b4 c2 --

2.

Carbohydrates of medicinal and

pharmaceutical importance: sugar

alcohols, monosaccharides and

disaccharides

a2-a6

b1- b4

c2, c5 --

3. Homopolysaccharides a2-a6 b1- b4 c2, c5 d1, d3

4. heteropolysaccharides + Quiz 1 a2-a6 b1- b4 c2, c5 d1, d3

5.

Bitter principles and other

miscellaneous natural products:

Furanochromones, Furancoumarins

a2, a5-a6 b3, b4 c2 d1, d3

6. Sesquiterpenes and lignans a2, a5-a6 b3, b4 c2 d1, d3

7. Miscellaneous Natural products a2, a5-a6 b3, b4 c2 d1, d3

9.

Essential oils, distribution and

occurrence, physiological significance

and effects and side effects.

a1-a6 b4 c4 d1, d3

10.

Methods of extraction of volatile oils,

Chemistry of volatile oils, classification

and biogenesis.

a2, a5 b1- b4 c2, c5 d1, d3

11. Terpene hydrocarbons, alcohols and

esters. a2, a3,a6 b1- b4 c2 d1, d3

12. Terpene aldehydes, ketones, and

phenols.

a2, a3,

a4,a6 b1- b4 c2, c5 d1, d3

13. Oxides, peroxides and miscellaneous. a2, a3,

a4,a6 b1- b4 c2, c5 d1, d3

8.2. Practical:

Study


ILOs

K&U IS P&PS G&TS

1. Qualitative Tests of Monosaccharides a2-a5 b1-b3,

b5 c1-c3, c5 d1- d3

2. Qualitative Tests of Disaccharides a2-a5 b1-b3,

b5 c1-c3, c5 d1- d3

3. Qualitative Tests of Polysaccharides a2-a5 b1-b3,

b5 c1-c3, c5 d1- d3

26 | P a g e

4. Revision Carbohydrate a4 b3 c1, c5 -

5. Carbohydrate practical exam

6. Assay of Clove oil a2, a5 b1-b3,

b5 c1-c3, c5

d1- d3

7. Assay of volatile oil containing

peroxide a2-a5

b1-b3,

b5 c1-c3, c5 d1- d3

9. Assay of volatile oil containing oxide a2, a3,

a4,a6

b1-b3,

b5 c1-c3, c5 d1- d3

10. Assay of Bitter almond oil by

Hydroxylamine method

a2, a3,

a4,a6

b1-b3,

b5 c1-c3, c5 d1- d3

11. Assay of volatile oil by bisulfite

method

a2, a3,

a4,a6

b1-b3,

b5 c1-c3, c5 d1- d3

12. Revision on volatile oils a4,a6 b1,b2,

b5 c1-c3 --

Name Signature

Course Coordinator: Dr. Amgad Ibrahim Mansour



27 | P a g e





Course Title: Phytochemistry-2

Course Code: PG 422



Academic year/ level: Fall Semester 2017/2018 Level four

Prerequisite: Phytochemistry-1 (PG 321)


2. Course Aims:

The course provides the students with an understanding of the chemical constituents of crude

drugs (alkaloids, glycosides, hallucinating and anticancer drugs found in different compound

classes) and the skills in extraction, separation, chemical structures, identification,

quantitative determination, medicinal uses and structure activity relationship of phyto-

constituents.




A1 a1

Discuss the basic principles of the chemistry of natural products (such as

alkaloids and glycosides) in synthesis, isolation, purification and identification of

plant active constituents.

A2 a2 Recognize the physico-chemical properties of natural products as alkaloids,

glycosides, hallucinating and anticancer drugs.

A3

a3 Understand principles of qualitative and quantitative determination of plant active

constituents (such as alkaloids, glycosides, hallucinating and anticancer drugs).

a4 Define the basis of phytochemical screening of medicinal plants for their active

constituents.

A4 a5 Enumerate the theories of isolation, synthesis, purification, identification and

standardization of natural products.

A13 a6

Recall the chemical and pharmacological properties natural products including

chemistry, nomenclature, mechanisms of action, therapeutic uses,

biotransformation, dosage, contraindications, adverse drug reactions, and drug

interactions.

28 | P a g e



B3. b1 Determine suitable methods of analysis and quality control of drugs as raw

material, in dosage forms and in biological fluids.

B5.

b2 Apply extraction processes to materials found in nature and resolving these

extracts into their pure constituents.

b3

Design appropriate methods for identification and standardization of various

chemical compounds (plant active constituents such as alkaloids, glycosides,

hallucinating and anticancer drugs found in different compound classes).

B9 b4 Select the proper drugs for various disease conditions.

B13. b5 Interpret experimental data based on relevant principles.




C4. c2 Select appropriate methods for extraction, isolation, synthesis, purification,

identification and standardization of active substances (of plant origin).

C8. c3 Manipulate pharmaceutical instruments and equipment safely and efficiently.

C9. c4 Utilize information on rational use of drugs and social health hazards of

abused and misused drugs of natural origin.

C11. c5 Conduct experimental and research studies, including: presentation, analysis

and interpretation of the results.



D2. d1 Retrieve pharmaceutical, clinical and other drug information resources.

D3. d2 Work effectively as a part of a team to perform the required tasks.

D6. d3 Develop the skills required for continued self-professional development and

self-learning.

4. Contents:

4.1.Lectures:

Study

week Topics

No. of

Credit Hours

1. Introduction and extraction of alkaloids 2

2. Classification of alkaloids 2

3. Pyridine and piperidine alkaloids 2

4. Alkaloidal amines and tropane alkaloids + Quiz 1 2

5. Quinoline and isoquinoline alkaloids 2

29 | P a g e

4.2.Practical:

Study

week Topics

No. of

Credit

Hours

1. Introduction to alkaloids chemistry + quinine identification 1

2. Identification of caffeine 1

3. Identification of ephedrine and papaverine 1

4. Identification of atropine 1

5. Identification of pilocarpine

1

6. Identification of strychnine and brucine 1

7. Introduction to column chromatography + planner chromatography 1

8. Quiz 2

9. Separation of tropane alkaloids using TLC 1

10. isolation of different dyes using paper chromatography

1

11. isolation of different dyes using column chromatography 1

12. Revision on alkaloid identification

1


14. Final Exam

Total:

1 credit

hour 15.

6. Indole and imidazole 2

7. Steroidal and purine alkaloids

2

8. Quiz 2

9. Introduction of medicinal glycosides, Alcoholic and phenolic

glycosides 2

10. Aldehydic and cyanogenic glycosides 2

11. Anthracene and steroidal glycosides 2

12. Coumarin, chromone, sulpher containing and alkaloidal

glycosides 2

13. Flavanoid glycosides, saponins and tannins 2

14. Final Exam

Total:

2 credit hours 15.

31 | P a g e


5.1 Lectures

5.2 Practical sessions

5.3 Homework

5.4 Brain storming

5.5 Learning management systems (Moodle)




skills.





and confidence.





Assessment 3 Assignment (Search topic and presentation) all over the term





1. Course work:

- Quiz 1 10

- Quiz 2 10

- Assignment (Search topic and presentation) 5


3. Oral Exam 10


Total 100%


No. Reference Type

1 Biren S., "Text Book of Pharmacognosy and Phytochemistry".

Elsevier, India. 2nd Edition (2013) Textbook

31 | P a g e

2

Trease G.E and Evans W.C.,''Pharmaconosy'', William C. Evans.

Edinburgh, London, new york, Philadelphia, Sydney, Toronto , 16th

Ed., (2017)

Textbook

3

phytochmistry

Natural products research

Chromatographia

Phytochemical analysis

Periodicals


8.1. Lectures:

Study


ILOs

K&U IS P&PS G&TS

1. Introduction and extraction of

alkaloids a1, a2, a5 b2 c2 -

2. Classification of alkaloids a1, a2, a6 b1 c2 -

3. Pyridine and piperidine alkaloids a2, a6 b1, b3, b4 c2 d1, d3

4. Alkaloidal amines and tropane

alkaloids + Quiz 1 a2-a4, a6 b1, b3, b4 c2, c5 d1, d3

5. Quinoline and isoquinoline alkaloids a2-a4, a6 b1, b3, b4 c2, c5 d1, d3

6. Indole and imidazole a2, a6 b1, b3, b4 c4, c5 d1, d3

7. Steroidal and purine alkaloids a2, a5, a6 b1- b3, b4 c2, c5 d1, d3

9. Introduction of medicinal glycosides,

Alcoholic and phenolic glycosides a1, a2, a6 b1, b3, b4 c2 d1, d3

10. Aldehydic and cyanogenic

glycosides a1, a2, a6 b1, b3, b4 c2, c5 d1, d3

11. Anthracene and steroidal glycosides a1, a2, a6 b1, b3, b4 c2, c5 d1, d3

12. Coumarin, chromone, sulpher

containing and alkaloidal glycosides a1, a2, a6 b1- b3, b4 c2, c5 d1, d3

13. Flavanoid glycosides, saponins and

tannins a1, a2, a6 b1, b3, b4 c2 d1, d3

8.2. Practical:

Study


ILOs

K&U IS P&PS G&TS

1. Introduction to alkaloids chemistry +

quinine identification a3-a4

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

2. Identification of caffeine a3-a4 b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

3. Identification of ephedrine and

papaverine a3-a4

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

32 | P a g e

4. Identification of atropine a3-a4 b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

5. Identification of pilocarpine a3-a4 b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

6. Identification of strychnine and brucine a3-a4 b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

7. Introduction to column chromatography

+ planner chromatography a3-a5

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

9. Separation of tropane alkaloids using

TLC a3-a5

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

10. isolation of different dyes using paper

chromatography a3-a5

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

11. isolation of different dyes using column

chromatography a3-a5

b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

12. Revision on alkaloid identification a3-a5 b1, b2,

b3, b5

c1, c2,

c3, c5 d2- d3

Name Signature

Course Coordinator: Prof. Dr. Fathy K. El Fiky


Approval Date 11.9.2017

33 | P a g e





Course Title: Phytotherapy

Course Code: PG 514



Academic year/ level: Spring Semester 2017/2018 Level four

Prerequisite: None


2. Course Aims:

To provide the students with an outline of the frequent practices of phytotherapy, give the

students the skills to understand the potential risks and benefits associated with medicines

from plants and to be able to evaluate their efficacy and provide a critical review of the

literature supporting and opposing the use of phytotherapy to treat atopic disorders.




A1

a1 Define phytotherapy and list the systems, modalities and practices

commonly included in phytotherapy.

a2 Explain the reasons for use of phytotherapy practices in contrast with

conventional medicine.

a3 Demonstrate an ability to use the principles of evidence based practice when

evaluating phytotherapy.

A13 a4

Describe the basic concepts of the most commonly used phytotherapy

modalities and systems, potential adverse effects, current research evidence

for efficacy and the training / credentialing standards and reputable of

practitioners.

a5

Acquire the background about the newly discovered novel effects of some

old remedies; understand area of its utilization and their mechanism of action

(like curcumin, liquorice, artemisinin, flavonoids, garlic and hirudin).



B9

b1 Specify the role of traditional medical systems in managing chronic medical

conditions.

b2

Apply acquired information to propose the consumption of certain herbs

with newly discovered effects that can either promote health condition in

general or protect the vital systems like cardiovascular system from the

adverse effects of thrombus formation.

34 | P a g e

B15 b3 Estimate health hazards concerning drug abuse, misuse and exposure to toxic

agents.

B22 b4 Integrate a suitable therapeutic plan for a patient and apply objective

assessment.

B11 b5. Assess possible drug interactions, adverse drug reactions, drug-disease

interactions and other drug-related problems.



C4 c1

Maintain professional competence through identifying, evaluating and

analyzing the accumulated natural products that might affect public health

promotion and/or disease prevention.

C9 c2 Raise public awareness on rational use of drugs and social health hazards of


C13 c3

Assess risks concerning drug interactions, adverse reactions and

incompatibilities in drug substances and different pharmaceutical

preparations.

C17 c4 Carry out duties and council patients in accordance with legal, ethical, social,

economic and professional guidelines.



D2 d1. Retrieve pharmaceutical and other drug information resources

D6 d2. Develop the skills required for continued self- professional development and

self- learning

4. Contents:

4.1.Lectures:

Study

week Topics

No. of

Credit Hours

1. Introduction into phytotherapy. 2

2. Modalities of phytotherapy. 4

3.

4. Herbal medicine, virtues and shortcomings of using herbal

medicines remedies + Quiz 1 2

5.

The proper herbal drugs for certain ailment in different

patients with representative examples (treatment of

constipation and treatment of asthma, management of

inflammations, peptic ulcer and therapeutic effects of

ginseng).

2

6.

The proper herbal drugs for certain ailment in different

patients with representative examples (treatment of

constipation and treatment of asthma, management of

inflammations, peptic ulcer and therapeutic effects of

ginseng).

2

35 | P a g e


5.1. Lectures

5.2. Self-learning (Search topics assignments and presentations)

5.3. Brain storming





skills.







Assessment 3 activity (Presentation of a part of the

course by students) all over the term


7. Factors affecting the activity of medicinal plants. 2

8. Quiz 2

9. Evaluation of phytotherapy claims and how Information

sources on phytotherapy should be utilized 2

10. Herb-drug interactions 2

11. Ochratoxins and pautulin. 2

12.

Renewed interest in some old remedies, curcumin, a new anti-

inflammatory agent, modern utilization of liquorice in peptic

ulcer, artemisinin, a new anti-malarial agent from plant

source.

2

13.

Natural products as the source of modern anti-thrombotic

drugs, new properties for flavonoids, new properties for garlic

and hirudin, a specific inhibitor of thrombin, from medicinal

leech.

2

14. Final Exam

Total:

2 credit hours 15.

36 | P a g e


1. Course work:

- Quiz 1 10

- Quiz 2 10

- activity (Presentation of a part of the course

by students) 5


Total 100%


No. Reference Type

1.

Bone, K. and Mills, S. "Principles and Practice of

Phytotherapy (Modern Herbal Medicine)". (Second Edition) (2013).

Elsevier, UK.

Textbook


8.1. Lectures:

Study


ILOs

K&U IS P&PS G&TS

1. Introduction into phytotherapy. a1 b1 c1, c2 --

2. Modalities of phytotherapy. a1, a4 b1 c1 --

3. Modalities of phytotherapy. a2, a3 b1 c1 d2

4.

Herbal medicine, virtues and

shortcomings of using herbal medicines

remedies

a4 b1, b3 c2 d1, d2

5.

The proper herbal drugs for certain

ailment in different patients with

representative examples (treatment of

constipation and treatment of asthma,

management of inflammations, peptic

ulcer and therapeutic effects of

ginseng)..

a4 b1- b4 c4

d1, d2

6.

The proper herbal drugs for certain

ailment in different patients with

representative examples (treatment of

constipation and treatment of asthma,

management of inflammations, peptic

ulcer and therapeutic effects of

ginseng)..

a1 b1, b4 c4 d1, d2

7. Factors affecting the activity of

medicinal plants. a3 b5 c2, c4 d1, d2

37 | P a g e

9.

Evaluation of phytotherapy claims and

how Information sources on

phytotherapy should be utilized

a4 b2-b4 c2, c4 d1

10. Herb-drug interactions a3, a4 b3, b5 c3 d2

11. Ochratoxins and pautulin. a5 b2 c2 d1

12.

Renewed interest in some old remedies,

curcumin, a new anti-inflammatory

agent, modern utilization of liquorice in

peptic ulcer, artemisinin, a new anti-

malarial agent from plant source.

a4, a5 b2-b4 c2 d1

13.

Natural products as the source of

modern anti-thrombotic drugs, new

properties for flavonoids, new

properties for garlic and hirudin, a

specific inhibitor of thrombin, from

medicinal leech.

a5 b2-b4 c4 d1

14.

Final Exam

15.

Name Signature

Course Coordinator: Prof. Dr. Fathy K. El Fiky

Head of Department: Prof. Dr. Amani Moukhtar Marzouk


38 | P a g e

Other Courses Not Opened for Registration

at Academic Year (2017-2018)

Final Approval 2016-2017

39 | P a g e


Course title: Herbal medicine Course code: PG 413


Department: Pharmacognosy

Academic level: Elective course

Prerequisite: None

Credit hours: Lecture: 2 Practical: - Total:2

2. Course Aims:

Providing the students with the knowledge of modern use of medicinal herbs in treatment,

their different dosage forms and methods of extraction and isolation of active constituents for

industry.

Also, providing examples the medicinal use of herbs in Egypt and other parts of the world.

Providing knowledge about the scientific basis of using herbs in treating certain ailments

concerning their active constituents and mode of action as well as discussing the national and

international legal regulation of herbal medicines industry and distribution.




A1.

a1 Define the concept of herbal medicine and the historical usage of herbal

remedies.

a2 Describe the correct use of herbs in treating or preventing certain disease.

a3 Discuss the different legal regulations governing usage, manufacturing and

distribution of herbal medicines

a4 List the mode of action of different plant secondary metabolites.

A4.

a5 Enumerate the different methods for standardization of natural products

a6 Identify the different methods for extraction and isolation of plant active

constituents and instruments used in industry.

A23 a7 Identify the principles of quality assurance (QA) of pharmaceutical processes and

products.

A24 a8 Distinguish appropriate GMP and QC criteria to different aspects of

pharmaceutical industry of herbal preparations.



B1 b1 Suggest some products and formulate recipes for patients.

B2 b2 Recommend good manufacturing practice in herbal industry

B3 b3 Determine suitable methods for analysis and quality control of raw material and

drugs in dosage forms.

B9

b4 Evaluate the value of a certain herbal preparations in treating or preventing a

disease.

b5 Identify other drugs outside his main study and determine their conformation with

pharmacopeial constants.

41 | P a g e



C10

c1 Employ the acquired scientific knowledge to council patients and safely and

prescribe some herbs in mild cases that do not require medical intervention.

c2 Develop the skills to prepare some simple recipes and herbal formulae according

to pharmacopeial criteria.

C14 c3

Employ the different qualitative and quantitative chemical and biological

methods for quality control and assay of raw material and pharmaceutical

preparations.

C17 c4 Utilize legal and ethical guidelines to ensure correct and safe supply of medical

products



D2 d1 Retrieve pharmaceutical and other drug information resources.

D3 d2 Work effectively as a part of a team and independently to perform the required

tasks.

D5 d3 Develop information technology (IT) skills.

D6 d4 Develop the skills required for continued self- professional development and self-

learning.

D9 d5 Acquire effective time-management skills.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

credit

hours

1.

Introduction & history of herbal medicine: Graeco-Roman and

Great Islamic medicine; Chinese Herbal Medicine; Ayurvedic

herbal medicine; 19th century North American herbal medicine.

2

2.

Legal Regulations of Herbal Medicines: Challenges related to the

regulatory status of herbal medicines; National Policies for

regulations of herbal medicines in Egypt and other parts of the

world.

2

3. General modes of action and pharmacology of plant secondary

metabolites 2

4. Herbal medicines classification disease-wise:

Antiacne and antipruriticherbs and recipes 2

5. Herbs for treating the respiratory system 2

6 Herbs for treating the cardiovascular system 2

7. MID-TERM EXAM

8. Herbs for treating the urinary system 2

9. Herbs for treating the muscloskeletal disorders. 2

10. Extraction, isolation, purification and quantification of active

constituents in medicinal herbs 2

41 | P a g e

11. Quality assurance of herbal preparations in different dosage forms. 2

12. Quality assurance of herbal preparations in different dosage forms. 2

13. Group seminars for presentation of required course activity 2

14. FINAL EXAM

2 credit

hours 15.


5.1. Lectures

5.2. Assignments and group discussion



1. Written exam to assess knowledge, understanding, intellectual and professional skills

3. Class work to assess knowledge, understanding, intellectual skills, general skills and

confidence

4. Quizzes to assess knowledge, understanding and intellectual skills


Assessment 1 Mid-term 7th week

Assessment 2 Assignment

discussion 12th week

Assessment 3 Written 14th &15th weeks


Mid-Term Exam & course work 25

Final-Term Exam 75

Total 100%


No. Reference type

1. Textbook of Natural Medicine (4th Edition). Joseph

Pizzorno, Michael Murray. Elsvier, USA (2012) textbook

2.

Herbal Drugs and Phytopharmaceuticals, A Hand Book for

Practice on Scientific Basis. Max Whichtel (ed.). MedPharm

Scientific Publisher, Stuttgart, Germany (2004) (translated

from German)

textbook

3. Mills S., Bone K., Principles and Practice of Phytotherapy.

Chirchil-Livingstone, New York. textbook

4. WHO monographs

Evidence-Based Complementary and Alternative Medicine periodicals

5. www.nih.gov, www.herbalgram.com website

6. National geography T.V channel

http://www.nih.gov/


42 | P a g e


Study

week Course contents

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1.

Introduction & history of herbal

medicine: Graeco-Roman and Great

Islamic medicine; Chinese Herbal

Medicine; Ayurvedic herbal

medicine; 19th century North

American herbal medicine;

a1 b3 c1 d1

2.

Legal Regulations of Herbal

Medicines: Challenges related to the

regulatory status of herbal

medicines; National Policies for

regulations of herbal medicines in

Egypt and other parts of the world

a3 b3 c4 d1

3.

General modes of action and

pharmacology of plant secondary

metabolites a4 b5 c1 d1

4.

Herbal medicines classification

disease-wise:

Antiacne and antipruriticherbs and

recipes

a2, a5 b1 c1, c2 d1

5. Herbs for treating the respiratory

system a2, a5 b1 c1, c2 d2-d5

6. Herbs for treating the cardiovascular


8. Herbs for treating the urinary


9. Herbs for treating the

muscloskeletal disorders. a2, a5 b1 c1, c2 d2-d5

10.

Extraction, isolation, purification

and quantification of active

constituents in medicinal herbs

a6 b2 c2, c3 d1, d3

11.

Quality assurance of herbal

preparations in different dosage

forms.

a7, a8 b2 c2, c3 d1, d3

12.

Quality assurance of herbal

preparations in different dosage

forms.

a7, a8 b2, b4 c2, c3 d1, d3

13. Group seminars for presentation of

required course activity a7, a8 b2, b4 c2, c3 d1, d3

Name Signature

Course Coordinator: Professor Dr. Amani M. Marzouk

Head of Department: Professor Dr. Fathy K. ElFiky


43 | P a g e


Course title: Marine Drugs Course code: PG515


Department: Pharmacognosy

Academic level: Elective course

Prerequisite: None

Credit hours: Lecture: 2 Practical: NA Total:2

2. Course Aims:

To provide the students with an outline of the marine products as potential therapeutic agents

and important products in the pharmaceutical industry. The course is intended to cover

classification, chemistry, identification and assay of marine natural products as well as an

outline of marine pharmacology.




A1 a1 Identify the basic principles of all aspects of the chemistry and pharmacology of

marine natural products

A4 a2 Enumerate the theories of isolation, purification and identification of marine

natural products.

A13 a3

Recall the chemical and pharmacological properties of drugs from marine origin

including chemistry, nomenclature, mechanisms of action, therapeutic uses,

contraindications, adverse drug reactions, and drug interactions.



B3 b1 Determine suitable methods of analysis and quality control of marine drugs as

raw material, in dosage forms and in biological fluids.

B5 b2

Design appropriate methods for isolation, purification, identification and

standardization of various chemicals and pharmaceutical compounds of marine

origin.

B9 b3 Select the proper drug for various disease condition

B15 b4 Estimate health hazards concerning exposure to toxic products



C4 c1 Select appropriate methods for extraction, isolation, purification and identification

of active substances from marine origin.

C7 c2 Assess toxicity profiles of different xenobiotics and detect toxins of marine origin

C9 c3 Raise public awareness on rational use of drugs and social health hazards of

abused and misused drugs of natural origin.

44 | P a g e



D2 d1 Retrieve pharmaceutical, clinical and other drug information resources.

D3 d2 Work effectively as a part of a team to perform the required tasks.

D5 d3 Develop information technology (IT) skills.

D6 d4 Develop the skills required for continued self-professional development and

self-learning.

D9 d5 Acquire effective time-management skills.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

credit

hours

1. Reasons to look for marine drugs, sources of marine drugs and potential

uses of marine drugs in the pharmaceutical field. 2

2. Collection & field identification of the Marine organisms. Initial extraction

of the Organism. Biological assay of the extract 2

3. Classification of marine drugs. Examples for Antibacterial and antifungal

agents from marine sources 2

4. Examples for anti-protozoal, anti-parasitic and antiviral agents from marine

sources 2

5. Examples for anti-cancer agents from marine sources 2

6. Examples for anti-spasmodic and anti-inflammatory

agents from marine sources 2

7. Mid-Term exam ---

8. Examples for anti-coagulants, Insecticides and Prostaglandins from marine

sources 2

9. Marine toxins 2

10. Symbiotic Bacteria in Sponges as Sources of Bioactive Substances 2

11. Pharmacology of marine drugs. 2

12. Pharmacology of marine drugs. 2

13. Search topics discussion and evaluation 2

14. Final Exam

2 credit

hours 15.


5.1. Lectures

5.2. Search topics assignments

45 | P a g e



1. Written exam to assess knowledge, understanding, intellectual and professional skills

2. Class work to assess knowledge, understanding, intellectual skills, general skills and

confidence

3. Assignments to assess the skills of problem-solving, self-learning and data presentation


Assessment 1 Mid-term 7th week

Assessment 2 Search topics discussion and evaluation 13th week

Assessment 3 Written 14th &15th weeks


Mid-Term Exam & course work 25 %

Final-Term Exam 75%

Total 100%


No. Reference type

1.

Handbook of Marine Natural Products. Fattorusso

Ernesto, Gerwick William H., Taglialatela-Scafati Orazio (Eds.)

(2012). Springer, Germany.

textbook

2.

Bhakuni D.S., Rawat, D.S. (2005): Bioactive Marine Natural

Products, Co-published by Springer, New York 10013, USA

with Anamaya Publishers, New Delhi, India.

textbook

3. Nobuhiro Fusetani (ed.).2000. Drugs from the Sea

Karger, Tokyo. textbook

4. Marine drugs periodical

5. National geographic TV channel


Study

week Course contents

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1.

Reasons to look for marine drugs,

sources of marine drugs and

potential uses of marine drugs in

the pharmaceutical field.

a1 b3 c3 d1, d2, d5

2.

Collection & field identification

of the Marine organisms. Initial

extraction of the Organism.

Biological assay of the extract

a1 b1, b2 c1 d3, d4

46 | P a g e

3.

Classification of marine drugs.

Examples for Antibacterial and

antifungal agents from marine

sources

a2, a3 b1, b2 c1, c2 d3, d4

4.

Examples for anti-protozoal, anti-

parasitic and antiviral agents from

marine sources

a1, a3 b1, b2 c1, c2 d3, d4

5. Examples for anti-cancer agents

from marine sources a1, a3 b1, b2 c1, c2 d3, d4

6.

Examples for anti-spasmodic and

anti-inflammatory

agents from marine sources

a1, a3 b1, b2 c1, c2 d3, d4

8.

Examples for anti-coagulants,

Insecticides and Prostaglandins

from marine sources

a1, a3 b1, b2 c1, c2 d3, d4

9. Marine toxins a3 b4 c2, c3 d3, d4

10. Symbiotic Bacteria in Sponges as

Sources of Bioactive Substances a1, a3 b1, b2 c2, c3 d3, d4

11. Pharmacology of marine drugs. a1, a3 b3, b4 c2, c3 d3, d4

12. Pharmacology of marine drugs. a3 b3, b4 c2, c3 d3, d4

13. Search topics discussion and

evaluation a3 b3, b4 c2, c3 d3, d4

Name Signature

Course Coordinator: ---

Head of Department: Prof. Fathy K. ElFiky


Documents

Department of Pharmacognosy Courses Specificationsdeltauniv.edu.eg/new/pharmacy/wp-content/uploads/Pharmacognosy-Specs... · Course Contents ILOs K&U IS P&PS G&TS 1. Plant cell structure