D Day 2Day 1Day 4Day 6 Day 1 Day 2 Day 4 Day 6 Biopsy Injury D0 D1 D2 D3 D4 D5 D6 Wound monitoring by endoscope & Intrarectal adminstration of LGG or HBSS

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Supplementary Figure S2 (continued) 50 uM 500 nM Control 50 nM5 uM d FPR1 KO WT wound FPR1 KO Control 2.5 x 10 9 cfu2.5 x cfu WT 2.5 x 10 8 cfu 2.5 x 10 7 cfu wound c