Dr.Rajarshi PATEL

E-mail: rajarshipatel1989@gmail.com, Phone: +91-9033231942

Assistant Professor //Research Scientist

Ph.D (Organic Chemistry) with nearly 4 years of industrial & academic experience; targeting assignments as

Research Scientist (Pharmaceutical industry) and Assistant Professor (Chemistry) Seeking research and development position in the Pharmaceutical industry.

Summary

4 years of experience as a lead researcher/principle research officer and as an assistant professor of chemistry. Comprehensive knowledge of organic chemistry, analytical chemistry and industrial chemistry, derived from extensive graduate training in USFDA approved pharmaceutical industry and gaining scintillating knowledge by executing as a research scientist. Multi-year of research has focused on organic synthesis, analytical sophisticated instrumental techniques, and target oriented drug designing. Research has provided pivotal information in understanding drugs interaction with body enzymes and related metabolism. Educational Background Ph.D. Shri Jagdishprasad Jabarmal Tibrewala University, Chemistry Department, Rajasthan Dissertation “Studies on synthesis of Chalcone and Pyrimidine derivatives of Heterocyclic compounds and their anti microbial activity” Supervisor: Proff. Dr.Kartik B. Vyas Oct.2013

M.Sc. Sardar Patel University, Industrial Chemistry Department, Vallabh Vidyanagar Thesis “Synthesis of Biodegradable Polymers from Agriculture waste” Adviser: Dr.Merlin Thomas May.2011

B.Sc. V.P & R.P.T.P Science College, Industrial Chemistry Department, Vallabh Vidyanagar Senior project “Biofuels from Vegetable oil”

Director: Dr.V.K.Sinha April.2009 Professional Experience

Industrial Experience: 1.7 - years (24/06/2011 – 29/01/2013) Work Place:

Amoli Organics Pvt. Ltd. (USFDA Approved Pharmaceutical Industry) (Jr. Research Officer - R&D)

Role: Conducting routine experiments and related synthesis. Shift management and laboratory management related work. Analyzing research data of synthesized compounds and reports the same to the seniors. Making scientific database of drugs and study the patent of synthesis and related possible

modifications. Characterized products via scanning electron microscope, BSE, and high-resolution optical

microscope. Determined and prepared necessary engineering calculations. Integrated the health services function into the department and restructured responsibilities to

provide greater focus on proactive safety and wellness programs. Corrected all audit deficiencies, performed root cause analysis, and submitted repair schedules

to operations department.

Actively responsible for guiding Discovery, Product Development and Clinical Research/Nutrition Science teams on priority projects.

Identification and validation of novel targets as starting points for new drug discovery programs.

Establishment of innovative in vitro pharmacology models either in the area of mast cells, macrophages or dorsal root ganglia.

Establishment of in vivo pharmacology models in inflammatory pain and/or visceral pain. Scientific planning, evaluation, interpretation and presentation of experimental studies. Collaboration in interdisciplinary project groups across various functions. Contribute to drug discovery projects by compound characterization in newly established

models. Works on a wide range of problems where analysis of situations or data requires evaluation of

intangible variables, requiring regular use of ingenuity and creativity.

Academic Experience: 3 – years (7/02/2013 – Present): Work Place:

Sardar Patel University (Assistant Professor, PhD Supervisor )

Role: Prepare and deliver lectures to students and conduct laboratory sessions or discussion groups Prepare, administer and grade examinations, laboratory assignments and reports. Advise students on course and academic matters and career decision. Conduct research in field of Chemistry and Applied Science and publish findings in scholarly

journals and also published books. Responsible for directing and executing scientific research for the development of drug

candidates or the research support of marketed drugs for industry. Investigates the feasibility of applying advanced principles and techniques of related scientific

specialty to products and problems faced by research students’ during synthesis. Actively participating in the development of state-of-the-art techniques to characterize

substances, assays and tools. Plans, designs, implements and analyses laboratory experimentation to advance scientific

knowledge of drug substances or drug products. Directs Research Associates or members of project teams in the initiation and execution of

laboratory experimentation, considering economic, regulatory and safety factors. Works on a wide range of problems where analysis of situations or data requires evaluation of

intangible variables, requiring regular use of ingenuity and creativity. Selected Skills and Techniques HPLC, XRD,NMR and GCMS Chemoffice Software proficiency Scifinder Chromatography Molecular binding and Protein

isolation Organic synthesis

Patent searching and publications searching

DNA and RNA isolation Drug discovery and Drug designing

Computer Skills: Word processing, spreadsheets, databases, design, web publishing. Leadership: Exceptional communication, organizational, public speaking and mentoring skills. Language: Bilingual English/Hindi and conversational in French. Honors and Awards Reviewer of Libertas Academica journal of Environmental Health Insights. Reviewer of Indian Journal of Pharmaceutical Research Scholar (IJPRS) Journal Amoli Organics (USFDA approved) awarded for process improvements of Rosuvastatin- -Calcium synthesis.

Institute of Science & Technology for Advanced Studies & Research (ISTAR), chemistry department, award for excellence teaching.

Professional Societies

American Chemical Society American Cancer Society Indian Chemical Society American association for cancer research American association for cell biology VCI - German Chemical Industry Association

Publications (20 research papers in National and International Journals)

Study on synthesis of Chalcone & Pyrimidine Heterocyclic compound & their Antimicrobial Activity, R.N. Patel1, K.S.Nimavat & K. B.Vyas, Asian Journal of Biochemical and Pharmaceutical Research, Issue 4 (Vol. 1) 2011.

Synthesis on Study of 2-Methyl-5-Nitro-N-(4-(3-(2-Aryl-2,3-Dihydrobenzo[B][1,4]Thiazepin-4-Yl)Phenoxy)Phenyl) Benzenesulfonamide And Their Antimicrobial Activity, Rajarshi N. Patel, K. S. Nimavat, K. B. Vyas And Piyush V. Patel, J. Chem. Pharm. Res., 2011, 3(6):409-415.

Synthesis on Study of 2-Methyl-5-Nitro-N-(4-(3-(5-Substituted-4,5- Dihydroisoxazol-3-Yl)Phenoxy)Phenyl)Benzenesulfonamide And Their Antimicobial Activity, Rajarshi N. Patel, K. S. Nimavat, K. B. Vyas And Piyush V. Patel, Der Pharma Chemica, 2011, 3 (6):334-340.

Synthesis of New Heterocyclic Schiff Base, Thiazolidinone And Azetidinone Compounds And Their Antibacterial Activity And Anti HIV Activities, Rajarshi N. Patel, P.V.Patel, K.R. Desai, P.Y. Purohit, K.S. Nimavat And K.B. Vyas, Heteroletters, 2: (1), 2012, 99-105.

Study And Synthesis of Some Organic Spiro Derivatives Using Schiff Base Reaction, Rajarshi N. Patel, P.V.Patel, K.R. Desai, K.S. Nimavat And K.B. Vyas, Heteroletters, 2: (3), 2012, 327-332.

Synthesis on Study of 2-Methyl-5-Nitro-N-(4-(3-(2-Oxo-6-Phenyl-1,2,5,6- Tetrahydro -pyrimidin-4-Yl)Phenoxy)Phenyl)Benzenesulfonamide And Their Antimicrobial Activity, Rajarshi N. Patel1, K.S. Nimavat, K.B. Vyas And Piyush V. Patel, Elixir org. Chem. 53 (2012) 11718-11721.

Synthesis on study of novel chalcone derivatives and their antimicrobial activity, Rajarshi N. Patel1 and Piyush V. Patel, European Journal of Experimental Biology, 2012, 2 (5):1492-1496.

Biological activity of newly synthesized M(II) heterochelates of coumarin derivative and Enrofloxacin, Rajarshi N. Patel, K.S..Patel, R.B.Patel, Heteroletters, 3: (4), 2013, 493-504.

A novel and industrial approach for the synthesis of Valsartan, Rajarshi N. Patel, K.S.Patel, R.B.Patel, D.S.Patel , Heteroletters, 3: (4), 2013, 513-518.

Synthesis on study Pyrazol derivatives and their antimicrobial activity, Rajarshi N. Patel and K.B.Vyas, World Journal of Science, 1: (1), 2013, 1-7.

synthesis of 2-methyl-5-nitro-n-(4-(3-((3-phenylquinoxalin-2-yl) methyl) phenoxy) phenyl) benzenesulfonamide and their antimicrobial activity, Rajarshi N. Patel, K.B. Vyas, Piysh V Patel And Dinesh S Patel, Heteroletters,2013,Vol. 3: (3), 341-347.

Synthesis on study Pyrazol derivatives and their antimicrobial activity, Rajarshi N. Patel and K.B.Vyas, World Journal of Medicine, 1: (2), 2013, 1-7.

Thermal and mechanical properties of Adipic Acid modified unsaturated polyester resin and jute composite, R. B. Patel, K. S. Patel, R. N. Patel, International Journal for Pharmaceutical Research Scholars (IJPRS), 2013, V-2,I-4.

Study on synthesis of 6-phenyl-4-(4-(4-(p-tolyloxy) phenoxy) phenyl)-5, 6-dihydro -pyrimidin -2(1H)-one and their antimicrobial activity, Rajarshi N. Patel, Hitesh Dave, K. S. Nimavat, K. B. Vyas and P. V. Patel, Archives of Applied Science Research, 5: (1), 2013, 40-44.

Thermal and mechanical properties of modified polyester resin and jute composite, R. B. Patel, K. S. Patel, R. N. Patel and K. D. Patel, Der Chemica Sinica, 2014, 5(1),47-54

Synthesis, thermal behavior and biological evaluation of dicoumarol cu(ii) complexes based on ciprofloxacin, ketan s patel, Rajarshi n patel, Heteroletters, 2014, vol. 4: (1), 23-33

Synthesis of some novel pyrimidinone and pyrimidine derivatives and their antimicrobial activity, Ketan S Patel, Rajarshi N Patel, Heteroletters, 4: (1), 2014, 119-124.

Water Analysis Based on Physico-Chemical Parameters in Anand District, Gujarat,Patel KS , Patel RN, Chhasatiya MR, Baser I, Patel DS, International Journal for Pharmaceutical Research Scholars (IJPRS), 2015,V-4, I-2.

Study on synthesis of novel chalcone their antimicrobial activity, ,Patel KS , Patel RN, Chhasatiya MR, Baser , Patel DS, Journal Club for Pharmaceutical Sciences (JCPS), 2015, V – 2, I – 1.

Chemical Study of Ground Water Taken From Highly Polluted Pond (Goya Talav) of Anand District (Gujarat), R. B. Patel, R. N. Patel, K. S. Patel, A. P. Desai, Journal Club for Applied Sciences (JCAS), 2015, V – 2, I – 1.

List of books published

Sr.No Title of Book Publisher ISBN Number Authors

1 Chemistry of Chalcone synthesis and its derivatives

Lambert Academic Publishing

978-3-659-67230-9

Dr. R.N.Patel Dr. K.S.Patel Dr. J.C.Patel

2

Biscoumarin and their transition metal complexes

Lambert Academic Publishing

978-3-659-64592-1

Dr. R.N.Patel Dr. J.C.Patel Dr. K.S.Patel

3

Transition metal heterochelates containing coumarin and clioquinol

Lambert Academic Publishing

978-3-659-74844-8

Dr. R.N.Patel Dr. K.S.Patel Dr. J.C.Patel

4

Basics of Chalcone and related novel synthesis

Lambert Academic Publishing

978-3-659-74680-2

Dr. R.N.Patel Dr. K.S.Patel Dr. J.C.Patel

Presentations and Conferences

Participated in the workshop on catalysis organized by the “Catalysis Society of India” on 25th March 2014, Baroda.

I have attended 48th Annual Convention of Chemists 2014, held at Gurukul Kangri University, Haridwar from 15 to 18th November, 2014 and presented a paper entitled. “Synthesis and antibacterial activity of chalcone and 1,5 Benzothiazepine derivatives”.

References Available upon request Dr.Rajarshi Patel